SEPSIS SEPTIC SHOCK UNFOLDING
REASONING EXAM SCRIPT
COMPREHENSIVE STUDY GUIDE
●● Risk factors for septic shock
Answer: Immunosuppression, hospitalization, malnourishment
Extremes of age (1 yr and 65 yr), infants w/infectious process, Chronic
illness, Invasive procedures, hospitalization
●● sepsis patho
Answer: bacteria cause immune response that leads to poor tissue
perfusion, increased capillary permeability leads to fluid leaking from
capillaries, & vasodilation interrupt bodies ability to adequately perfuse,
oxygenate & distribute nutrients
●● more sepsis patho
Answer: inflammatory response activates coagulation system, body
forms clots whether needs them or not
●● Early phase or warm phase
Answer: BP WDL or hypotensive but responsive to fluids. HR increases
to tachycardia, hyperthermia, bounding pulses are evident.
, ●● What happens to urinary & GI
Answer: urine @ normal levels or decreased, GI nausea, vomiting,
diarrhea, or decreased bowel sounds
●● What are some signs of hyper metabolism with sepsis
Answer: increased serum glucose and insulin resistance
●● What are some mental status changes
Answer: Subtle changes in mental status, such as confusion or agitation,
may be present.
●● What are some labs seen
Answer: The lactate level is elevated because of the maldistribution of
blood. Inflammatory markers such as white blood cell counts and C-
reactive protein are also elevated
●● Progression of sepsis causes
Answer: less tissue perfusion, acidotic, compensatory mechanisms fail,
pt shows signs of organ dysfunction, bp doesn't respond to fluid and
vasoactive agents, signs of end organ damage are evident
●● What are some signs of end organ damage
Answer: renal failure, pulmonary failure, hepatic failure
REASONING EXAM SCRIPT
COMPREHENSIVE STUDY GUIDE
●● Risk factors for septic shock
Answer: Immunosuppression, hospitalization, malnourishment
Extremes of age (1 yr and 65 yr), infants w/infectious process, Chronic
illness, Invasive procedures, hospitalization
●● sepsis patho
Answer: bacteria cause immune response that leads to poor tissue
perfusion, increased capillary permeability leads to fluid leaking from
capillaries, & vasodilation interrupt bodies ability to adequately perfuse,
oxygenate & distribute nutrients
●● more sepsis patho
Answer: inflammatory response activates coagulation system, body
forms clots whether needs them or not
●● Early phase or warm phase
Answer: BP WDL or hypotensive but responsive to fluids. HR increases
to tachycardia, hyperthermia, bounding pulses are evident.
, ●● What happens to urinary & GI
Answer: urine @ normal levels or decreased, GI nausea, vomiting,
diarrhea, or decreased bowel sounds
●● What are some signs of hyper metabolism with sepsis
Answer: increased serum glucose and insulin resistance
●● What are some mental status changes
Answer: Subtle changes in mental status, such as confusion or agitation,
may be present.
●● What are some labs seen
Answer: The lactate level is elevated because of the maldistribution of
blood. Inflammatory markers such as white blood cell counts and C-
reactive protein are also elevated
●● Progression of sepsis causes
Answer: less tissue perfusion, acidotic, compensatory mechanisms fail,
pt shows signs of organ dysfunction, bp doesn't respond to fluid and
vasoactive agents, signs of end organ damage are evident
●● What are some signs of end organ damage
Answer: renal failure, pulmonary failure, hepatic failure
