Pharmacology Comprehensive Final Exam TTUHSCSON NURS 3107
Texas Tech University Health Sciences Center | UPDATED Questions
with 100% Verified Answers
Question:
Pharmacokinetics
Answer:
-How the medication moves through the body
-How the body acts upon the medication
Question:
Absorption
Answer:
Medication routes dictate the rate of onset and bioavailability
Question:
Distribution
Answer:
-Medications are distributed through the blood stream
-Areas with low blood flow will have lower concentration of
medication
Question:
Metabolism
Answer:
Liver is the primary sight of medication metabolism
Question:
If the liver is damaged
Answer:
-It will not be able to metabolize medications as effectively
-May lead to toxicity
,Question:
Labs for Liver Function
Answer:
-AST
-ALT
Question:
Clinical S/Sx of Liver Damage
Answer:
-Anorexia
-Nausea
-Vomiting
-Abdominal Distention
-Jaundice
Question:
Hepatotoxicity
Answer:
Medications or substances (ETOH) that cause liver damage
Question:
First Pass Effect
Answer:
Enteral medications (medications that are absorbed through
the GI tract) will be affected
Question:
Excretion
Answer:
The kidneys are the primary sight of medication excretion
Question:
If the kidneys are damaged
, Answer:
-They will not be able to excrete medications as effectively
-May lead to toxicity
Question:
Labs for Kidney Function
Answer:
-BUN
-Creatinine
Question:
Clinical S/Sx of Kidney Damage
Answer:
-Decreased/absent urine output (UO)
-UO less than 30 ml/hr
-Edema
-Sudden and rapid weight gain
-Dark urine
Question:
Nephrotoxicity
Answer:
Medications or substances that causes kidney damage
Question:
Geriatric Considerations
Answer:
-Decreased liver and kidneys function will decrease
metabolism and excretion of medications
-Increases the risk for toxicity
Question:
Pediatric Considerations
, Answer:
-Immature liver and kidneys
-Slower metabolism and excretion of medications
-Increases the risk for toxicity
Question:
Pregnant & Breast Feeding considerations
Answer:
-Anything mom receives the baby also receives
-Ensure medications are safe
Question:
High or Wide Therapeutic Index/Window
Answer:
Medication is considered generally safe
Question:
Low or Narrow Therapeutic Index/Window
Answer:
-Medication is considered dangerous
-Requires close monitoring
Question:
Peak
Answer:
-The point at which the medication concentration in the blood
is highest
-Medication dependent
Question:
Trough
Answer:
Texas Tech University Health Sciences Center | UPDATED Questions
with 100% Verified Answers
Question:
Pharmacokinetics
Answer:
-How the medication moves through the body
-How the body acts upon the medication
Question:
Absorption
Answer:
Medication routes dictate the rate of onset and bioavailability
Question:
Distribution
Answer:
-Medications are distributed through the blood stream
-Areas with low blood flow will have lower concentration of
medication
Question:
Metabolism
Answer:
Liver is the primary sight of medication metabolism
Question:
If the liver is damaged
Answer:
-It will not be able to metabolize medications as effectively
-May lead to toxicity
,Question:
Labs for Liver Function
Answer:
-AST
-ALT
Question:
Clinical S/Sx of Liver Damage
Answer:
-Anorexia
-Nausea
-Vomiting
-Abdominal Distention
-Jaundice
Question:
Hepatotoxicity
Answer:
Medications or substances (ETOH) that cause liver damage
Question:
First Pass Effect
Answer:
Enteral medications (medications that are absorbed through
the GI tract) will be affected
Question:
Excretion
Answer:
The kidneys are the primary sight of medication excretion
Question:
If the kidneys are damaged
, Answer:
-They will not be able to excrete medications as effectively
-May lead to toxicity
Question:
Labs for Kidney Function
Answer:
-BUN
-Creatinine
Question:
Clinical S/Sx of Kidney Damage
Answer:
-Decreased/absent urine output (UO)
-UO less than 30 ml/hr
-Edema
-Sudden and rapid weight gain
-Dark urine
Question:
Nephrotoxicity
Answer:
Medications or substances that causes kidney damage
Question:
Geriatric Considerations
Answer:
-Decreased liver and kidneys function will decrease
metabolism and excretion of medications
-Increases the risk for toxicity
Question:
Pediatric Considerations
, Answer:
-Immature liver and kidneys
-Slower metabolism and excretion of medications
-Increases the risk for toxicity
Question:
Pregnant & Breast Feeding considerations
Answer:
-Anything mom receives the baby also receives
-Ensure medications are safe
Question:
High or Wide Therapeutic Index/Window
Answer:
Medication is considered generally safe
Question:
Low or Narrow Therapeutic Index/Window
Answer:
-Medication is considered dangerous
-Requires close monitoring
Question:
Peak
Answer:
-The point at which the medication concentration in the blood
is highest
-Medication dependent
Question:
Trough
Answer:
