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NAPLEX Infectious Diseases IV Questions with Correct Answers (Grade A+)

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NAPLEX Infectious Diseases IV Questions with Correct Answers (Grade A+)

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NAPLEX Infectious Diseases IV Questions with Correct Answers
(Grade A+)

Question 1: When would a patient be considered immunocompromised?

Answer: HIV with CD4 <200; systemic steroids e14d with prednisone e20mg/d or e2mg/kg/d; asplenia;
autoimmune/SOT immunosuppressants; chemo with ANC <500

Question 2: PJP/PCP primary prophylaxis indications

Answer: CD4 <200

Question 3: PJP/PCP primary ppx

Answer: Bactrim DS or SS QD; Bactrim DS 3x/wk; Dapsone (+ pyrimethamine + leucovorin); Atovaquone
(+ pyrimethamine + leucovorin); inhaled pentamidine

Question 4: When can PJP/PCP primary ppx be stopped?

Answer: CD4 >200 on ART x3mo

Question 5: What should be used for PJP/PCP primary ppx in pts with sulfa allergies?

Answer: Dapsone (+ pyrimethamine + leucovorin) or atovaquone (+ pyrimethamine + leucovorin) or
inhaled pentamidine

Question 6: What should be used for PJP/PCP primary ppx in pts with G6PD deficiency?

Answer: atovaquone or pentamidine

Question 7: Toxoplasma gondii primary ppx indications

Answer: CD4 <100 and IgG positive

Question 8: Toxoplasma gondii primary ppx

Answer: Bactrim DS or SS QD or 3x/wk; Dapsone + pyrimethamine + leucovorin; atovaquone (+
pyrimethamine + leucovorin)

Question 9: Can dapsone monotherapy be used for Toxoplasma ppx?

Answer: no, need pyrimethamine and leucovorin




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