NURS 660 Psychopharmacology Exam 2 | NEWEST VERSION |
UPDATED ACTUAL QUESTIONS AND VERIFIED ANSWERS
• The pt is bipolar, and had a partial response to depakote and now is going to be
augmented with an atypical antipsychotic, the effects of atypical antipsychotics in
non-psychotic mania may be due to what -✓✓ANSWER: indirect effect on
glutamate release via 5H2A antagonism
• A pt has had some success with his current antidepression medication, has tried
many different antidepressants, so you decide to augment with L-methyl-folate.
What is the hypothesis behind L methyl Folate boosting the therapeutic efficacy of
antidepressants...what is the MOA? -✓✓ANSWER: boosts monamine
neurotransmitter function in bipolar disorder
• You have a pt that has been very depressed and has insomnia problems with
concentrations, weight loss and SI. You start them on an AD and his symptoms
have abated, however which of the following symptoms is the most likely to be
residual following the successful tx of other symptoms? -✓✓ANSWER: insomnia
• Which class of antidepressant have a lower incidence of sexual SE? What
medication is used in the tx of BP/mania and is used in prophylaxis as well as
antidepressant augmentation? Which medication is this? -✓✓ANSWER:
Wellbutrin
• What medication is a very potent CYP450 inhibitor and can dangerously elevate
lamotrigine? -✓✓ANSWER: Valproate
• Which class of antidepressant has the worst discontinuation syndrome? -
✓✓ANSWER: Cymbalta
, • You have a female pt complaining of lactating and is not pregnant w/ no children.
She has been taking risperidone. Which medication would you avoid if you were to
switch her to another med?" -✓✓ANSWER: Paliperidone
• A pt is on Prozac and it has stopped working. Patient has been on many other
antidepressants and wants to try an MAOI now. How long do you need to stop
Prozac before starting MAOI? -✓✓ANSWER: 5-6 weeks
• What neurotransmitter are affected by TCAs? -✓✓ANSWER: Serotonin,
dopamine, norepinorphrenie, 5HT
• What TCA medication should absolutely not be used in combination with any
other MAOI? -✓✓ANSWER: chlomipramine
• Please know what is the most potent property of trazodone by what
neurotransmitter? -✓✓ANSWER: SEDATION; 5H2A
• Patient prescribed Clomipramine suddenly stops taking medication. What side
effects could be shown? -✓✓ANSWER: Cardiovascular, coma, seizure, death
• What neurotransmitters are effected by tricyclic antidepressants -✓✓ANSWER:
increase levels of norepinephrine and serotonin, and block the action of
acetylcholine
• You have a patient that has rapid cycling bipolar disorder. Which combination
that should be given together? -✓✓ANSWER: lithium and lurasideon, lamotrigine
and quetiapine
UPDATED ACTUAL QUESTIONS AND VERIFIED ANSWERS
• The pt is bipolar, and had a partial response to depakote and now is going to be
augmented with an atypical antipsychotic, the effects of atypical antipsychotics in
non-psychotic mania may be due to what -✓✓ANSWER: indirect effect on
glutamate release via 5H2A antagonism
• A pt has had some success with his current antidepression medication, has tried
many different antidepressants, so you decide to augment with L-methyl-folate.
What is the hypothesis behind L methyl Folate boosting the therapeutic efficacy of
antidepressants...what is the MOA? -✓✓ANSWER: boosts monamine
neurotransmitter function in bipolar disorder
• You have a pt that has been very depressed and has insomnia problems with
concentrations, weight loss and SI. You start them on an AD and his symptoms
have abated, however which of the following symptoms is the most likely to be
residual following the successful tx of other symptoms? -✓✓ANSWER: insomnia
• Which class of antidepressant have a lower incidence of sexual SE? What
medication is used in the tx of BP/mania and is used in prophylaxis as well as
antidepressant augmentation? Which medication is this? -✓✓ANSWER:
Wellbutrin
• What medication is a very potent CYP450 inhibitor and can dangerously elevate
lamotrigine? -✓✓ANSWER: Valproate
• Which class of antidepressant has the worst discontinuation syndrome? -
✓✓ANSWER: Cymbalta
, • You have a female pt complaining of lactating and is not pregnant w/ no children.
She has been taking risperidone. Which medication would you avoid if you were to
switch her to another med?" -✓✓ANSWER: Paliperidone
• A pt is on Prozac and it has stopped working. Patient has been on many other
antidepressants and wants to try an MAOI now. How long do you need to stop
Prozac before starting MAOI? -✓✓ANSWER: 5-6 weeks
• What neurotransmitter are affected by TCAs? -✓✓ANSWER: Serotonin,
dopamine, norepinorphrenie, 5HT
• What TCA medication should absolutely not be used in combination with any
other MAOI? -✓✓ANSWER: chlomipramine
• Please know what is the most potent property of trazodone by what
neurotransmitter? -✓✓ANSWER: SEDATION; 5H2A
• Patient prescribed Clomipramine suddenly stops taking medication. What side
effects could be shown? -✓✓ANSWER: Cardiovascular, coma, seizure, death
• What neurotransmitters are effected by tricyclic antidepressants -✓✓ANSWER:
increase levels of norepinephrine and serotonin, and block the action of
acetylcholine
• You have a patient that has rapid cycling bipolar disorder. Which combination
that should be given together? -✓✓ANSWER: lithium and lurasideon, lamotrigine
and quetiapine
