Nurs 660 Psychopharmacology Exam 2 | Updated Actual Questions | A+ Verified Answers And Study Guide

NURS 660 Psychopharmacology Exam 2 | UPDATED
ACTUAL QUESTIONS | A+ VERIFIED ANSWERS AND
STUDY GUIDE
• How long does it take Fluoxetine (Prozac) to leave your system? -✓✓ANSWER:
5 weeks (d/t long half-life)


• Switching from an MAOI to a serotonergic Drug = _____ days -✓✓ANSWER:
14 days (2 weeks)


• Fluoxetine (Prozac) MOA? -✓✓ANSWER: Blocks serotonin reuptake pump;
Also has 5HT2C antagonist properties, which could increase NE and DA


• Fluoxetine (Prozac) MOA: Blocks serotonin reuptake pump; Also has _____
antagonist properties, which could increase NE and DA -✓✓ANSWER: 5HT2C


• What SSRI? May be activating/energizing (*might not be good for an
anxious/overacted patient) -✓✓ANSWER: Fluoxetine (Prozac)


• What SSRI? Improve concentration/motivation (*good choice for
sluggish/unmotivated patient b/c 5HT2C antagonism -> increase NE and DA) -
✓✓ANSWER: Fluoxetine (Prozac)


• What SSRI? Very long half-life (2 weeks); Good for noncompliant patients (less
likely to have withdrawal symptoms) -✓✓ANSWER: Fluoxetine (Prozac)


• Sertraline (Zoloft) MOA: blocks serotonin reuptake pump; Also has some ability
to block what? -✓✓ANSWER: dopamine reuptake pump (DAT) (which could
increase DA)

, • Sertraline (Zoloft) MOA: blocks serotonin reuptake pump; Also has some ability
to block dopamine reuptake pump (DAT); Also binds at what receptors? -
✓✓ANSWER: sigma 1 receptors (May help with anxiolytic effects and addressing
psychotic/delusional depression)


• What SSRI? May be useful for atypical depressive symptoms (hypersomnia,
anergia, mood reactivity) -✓✓ANSWER: Sertraline (Zoloft)


• What SSRI? Tends to be the agent of choice for pregnant/breastfeeding women -
✓✓ANSWER: Sertraline (Zoloft)


• Paroxetine (Paxil) MOA: blocks serotonin reuptake; Has mild _____ actions,
mild NET reuptake actions (further antidepressant actions), and inhibits nitric
oxide synthesis (sexual dysfunction) -✓✓ANSWER: anticholinergic


• Paroxetine (Paxil) MOA: blocks serotonin reuptake; Has mild anticholinergic
actions, mild NET reuptake actions (further antidepressant actions), and inhibits
_____ _____ synthesis (sexual dysfunction) -✓✓ANSWER: nitric oxide


• What SSRI MOA? blocks serotonin reuptake; Has mild anticholinergic actions,
mild NET reuptake actions (further antidepressant actions), and inhibits nitric
oxide synthesis (sexual dysfunction) -✓✓ANSWER: Paroxetine (Paxil)


• What are 2 common side effects of Paroxetine (Paxil)? -✓✓ANSWER: weight
gain & sexual dysfunction


• What SSRI? NOTORIOUS for withdrawal reactions if stopped suddenly (may be
d/t anticholinergic rebound?) -✓✓ANSWER: Paroxetine (Paxil)