ADVANCED PATHOPHYSIOLOGY
STUDY GUIDE CHAP 3-4 QUIZ 2027
WITH 120 QUESTIONS AND
EXPERT-VERIFIED CORRECT
ANSWERS | ALREADY GRADED
A+ | GUARANTEED SUCCESS
What are the three types of non Hodgkin lymphoma? - ANSWER-a. Burkitt
lymphoma
b. Lymphoblastic lymphoma
c. Large cell lymphoma
Which of the following is a common feature of all forms of leukemia? -
ANSWER-Uncontrolled
,proliferation of malignant leukocytes causing an overcrowding of bone marrow
and
abnormal hematopoiesis
A patient with myelodysplastic syndrome is at risk for the development of which
of
the following types of hematologic cancer? - ANSWER-Acute myelogenous
leukemia
Which chromosomal abnormality is commonly associated with chronic
myelogenous
leukemia? - ANSWER-Translocation of chromosome 9 and 22 leading to a fusion
protein known as BCR-ABL
The Philadelphia chromosome present in patients with? - ANSWER-Chronic
myelogenous leukemia
Abnormal immunoglobulins known as M proteins and free light chains produced
by
plasma cells are characteristic of - ANSWER-multiple myeloma.
Multiple myeloma characteristics and what electrolyte imbalance is present? -
ANSWER-Hypercalcemia - Bone breakdown causes release of Calcium.
A 66-year-old black man comes in complaining of back pain. Diagnostic tests are
done and include an X-ray, a complete blood count with differential, and a
comprehensive metabolic panel (e.g., glucose, potassium, calcium, albumin).
Which findings are consistent with multiple myeloma? - ANSWER-Diffuse well-
defined "punched out" lytic lesions
, - In MM abnormal plasma cells make monoclonal (one type of) antibodies. Tests
are
conducted to detect monoclonal antibodies in bone marrow, urine, or blood as well
as one or more of the CRAB features (hyperCalcemia, Renal failure, Anemia and
Bone
problems)
Which chromosomal abnormality is commonly associated with chronic
myelogenous leukemia? - ANSWER-Translocation of chromosome 9 and 22
leading to a fusion protein known as BCR-ABL
Philadelphia chromosome - ANSWER-created during translocation on
chromosome 9 and
chromosome 22 resulting in BCR-ABL fusion gene.
the Philadelphia chromosome present in patients with - ANSWER-Chronic
myelogenous leukemia
What are the immature precursor leukocyte cells associated with leukemia -
ANSWER-Myelodysplastic syndromes (MDSs) are a group of diseases where the
bone marrow doesn't make enough healthy mature blood cells. The immature
blood cells, called blast cells (blasts), do not work properly. They build up in the
bone marrow and the blood and crowd out healthy blood cells.
What Type of hematologic cancer should be suspected on a pediatric patient with
only symptoms: hepatomegaly and splenomegaly, small bruises? - ANSWER-
Acute lymphoblastic leukemia
A 5-year-old child is brought in by his parents who report that she has not been
eating well, and they think she is losing weight even though her belly looks
STUDY GUIDE CHAP 3-4 QUIZ 2027
WITH 120 QUESTIONS AND
EXPERT-VERIFIED CORRECT
ANSWERS | ALREADY GRADED
A+ | GUARANTEED SUCCESS
What are the three types of non Hodgkin lymphoma? - ANSWER-a. Burkitt
lymphoma
b. Lymphoblastic lymphoma
c. Large cell lymphoma
Which of the following is a common feature of all forms of leukemia? -
ANSWER-Uncontrolled
,proliferation of malignant leukocytes causing an overcrowding of bone marrow
and
abnormal hematopoiesis
A patient with myelodysplastic syndrome is at risk for the development of which
of
the following types of hematologic cancer? - ANSWER-Acute myelogenous
leukemia
Which chromosomal abnormality is commonly associated with chronic
myelogenous
leukemia? - ANSWER-Translocation of chromosome 9 and 22 leading to a fusion
protein known as BCR-ABL
The Philadelphia chromosome present in patients with? - ANSWER-Chronic
myelogenous leukemia
Abnormal immunoglobulins known as M proteins and free light chains produced
by
plasma cells are characteristic of - ANSWER-multiple myeloma.
Multiple myeloma characteristics and what electrolyte imbalance is present? -
ANSWER-Hypercalcemia - Bone breakdown causes release of Calcium.
A 66-year-old black man comes in complaining of back pain. Diagnostic tests are
done and include an X-ray, a complete blood count with differential, and a
comprehensive metabolic panel (e.g., glucose, potassium, calcium, albumin).
Which findings are consistent with multiple myeloma? - ANSWER-Diffuse well-
defined "punched out" lytic lesions
, - In MM abnormal plasma cells make monoclonal (one type of) antibodies. Tests
are
conducted to detect monoclonal antibodies in bone marrow, urine, or blood as well
as one or more of the CRAB features (hyperCalcemia, Renal failure, Anemia and
Bone
problems)
Which chromosomal abnormality is commonly associated with chronic
myelogenous leukemia? - ANSWER-Translocation of chromosome 9 and 22
leading to a fusion protein known as BCR-ABL
Philadelphia chromosome - ANSWER-created during translocation on
chromosome 9 and
chromosome 22 resulting in BCR-ABL fusion gene.
the Philadelphia chromosome present in patients with - ANSWER-Chronic
myelogenous leukemia
What are the immature precursor leukocyte cells associated with leukemia -
ANSWER-Myelodysplastic syndromes (MDSs) are a group of diseases where the
bone marrow doesn't make enough healthy mature blood cells. The immature
blood cells, called blast cells (blasts), do not work properly. They build up in the
bone marrow and the blood and crowd out healthy blood cells.
What Type of hematologic cancer should be suspected on a pediatric patient with
only symptoms: hepatomegaly and splenomegaly, small bruises? - ANSWER-
Acute lymphoblastic leukemia
A 5-year-old child is brought in by his parents who report that she has not been
eating well, and they think she is losing weight even though her belly looks
