HEMODIALYSIS NURSING QUESTIONS
AND CORRECT ANSWERS (VERIFIED
ANSWERS) PLUS RATIONALES 2026 Q&A
| INSTANT DOWNLOAD PDF Through
multiple-choice and scenario-based
items, candidates will demonstrate
mastery of prioritization, safety, and
clinical decision-making in the dialysis
setting
Core Domains
Renal Physiology and Chronic Kidney Disease
Hemodialysis Principles and Dialyzer Function
Vascular Access Assessment and Cannulation
Intradialytic Complications and Emergency Management
Dialysis Adequacy and Prescription Parameters
Fluid and Electrolyte Management
Infection Control and Water Treatment
Pharmacology and Anemia Management
Patient Education and Nutrition
Professional Standards and Safety Protocols
Introduction
This comprehensive examination is designed to assess the candidate's
knowledge and clinical judgment in hemodialysis nursing, preparing them for
the DaVita RN Final Exam. The assessment covers foundational renal
,physiology, hemodialysis principles, vascular access care, intradialytic
complications, dialysis adequacy, infection control, and evidence-based
patient management. Through multiple-choice and scenario-based items,
candidates will demonstrate mastery of prioritization, safety, and clinical
decision-making in the dialysis setting. This test bank emphasizes the
application of clinical judgment required for safe, patient-centered
hemodialysis nursing care.
SECTION ONE: QUESTIONS 1–100
1. During hemodialysis, urea moves from the blood compartment to
the dialysate compartment primarily through which mechanism?
A. Ultrafiltration
B. Convection
C. Diffusion
D. Osmosis
C. Diffusion
RATIONALE: Diffusion is the primary mechanism for solute removal in
hemodialysis. Urea and other small molecular weight solutes move across
the semipermeable membrane from an area of higher concentration (blood)
to lower concentration (dialysate) along the concentration gradient. The
countercurrent flow design maximizes this gradient along the entire length of
the dialyzer.
2. A patient requires removal of 3.5 kg of fluid during a 4-hour
dialysis treatment. What is the required ultrafiltration rate?
A. 500 mL/hr
B. 875 mL/hr
C. 1,000 mL/hr
D. 1,200 mL/hr
B. 875 mL/hr
RATIONALE: Ultrafiltration rate calculation: 3.5 kg = 3,500 mL. 3,500 mL
÷ 4 hours = 875 mL/hr. The ultrafiltration rate should generally not exceed
10–13 mL/kg/hr to minimize intradialytic hypotension and cramping.
3. Which characteristic best describes a high-flux dialyzer
membrane?
,A. Pore size that allows only small solutes (urea, creatinine) to pass
B. Increased permeability to middle molecules (β2-microglobulin, 11,800
Da)
C. Requires lower blood flow rates for equivalent clearance
D. Cannot be used with standard dialysis machines
B. Increased permeability to middle molecules (β2-microglobulin, 11,800
Da)
RATIONALE: High-flux dialyzers have larger pore sizes and higher
hydraulic permeability (KUF >20 mL/hr/mmHg), allowing removal of middle
molecules such as β2-microglobulin (11,800 Da) in addition to small solutes.
This reduces amyloidosis risk.
4. In countercurrent flow dialysis, blood and dialysate flow in
opposite directions. What is the primary advantage of this design?
A. Reduces the risk of air embolism
B. Maintains a concentration gradient along the entire dialyzer length
C. Allows for higher ultrafiltration rates
D. Prevents dialyzer clotting
B. Maintains a concentration gradient along the entire dialyzer length
RATIONALE: Countercurrent flow maintains the steepest possible
concentration gradient between blood and dialysate along the entire length
of the dialyzer. If flows were concurrent, the gradient would diminish as
fluids approached equilibrium. This design maximizes solute clearance
efficiency.
5. A patient's dialysate sodium is set at 138 mEq/L. The patient's
serum sodium is 140 mEq/L. Which direction will sodium move
during dialysis?
A. From dialysate to blood
B. From blood to dialysate
C. No net movement will occur
D. Movement depends on blood flow rate
B. From blood to dialysate
RATIONALE: Sodium moves by diffusion from higher to lower
concentration. With serum sodium (140 mEq/L) higher than dialysate
, sodium (138 mEq/L), sodium will move from blood to dialysate. This 2
mEq/L gradient promotes mild sodium removal.
6. Which solute is primarily removed by convection rather than
diffusion during hemodialysis?
A. Urea (60 Da)
B. Creatinine (113 Da)
C. β2-microglobulin (11,800 Da)
D. Phosphate (96 Da)
C. β2-microglobulin (11,800 Da)
RATIONALE: Convection (solvent drag) is the primary mechanism for
middle molecule removal such as β2-microglobulin (11,800 Da) during high-
flux dialysis and hemodiafiltration. Small solutes (urea, creatinine,
phosphate) are primarily removed by diffusion.
7. A patient is receiving dialysis with a dialysate temperature of
36.5°C. The patient reports feeling cold and shivering. Which
adjustment should the RN consider?
A. Increase the dialysate temperature to 38.0°C
B. Increase the dialysate temperature to 37.0°C and assess for sepsis
C. Decrease the dialysate temperature to 35.5°C to improve clearance
D. No adjustment; cold intolerance is expected during dialysis
B. Increase the dialysate temperature to 37.0°C and assess for sepsis
RATIONALE: Standard dialysate temperature is 35.5–37.0°C. A patient
feeling cold with shivering may indicate dialysate temperature too low or
sepsis. The RN should increase dialysate temperature toward 37.0°C and
assess for infection.
8. The principle of ultrafiltration in hemodialysis is best described
as:
A. Movement of solutes across a concentration gradient
B. Movement of fluid across a hydrostatic or osmotic pressure gradient
C. Binding of toxins to dialysate components
D. Active transport of electrolytes against their gradient
B. Movement of fluid across a hydrostatic or osmotic pressure gradient