LEIK FNP Exam Practice Questions (2026) –
Questions & Answers
Family Nurse Practitioner Board Exam Prep | Updated for AANP &
ANCC Blueprints
EXAM OVERVIEW
The Family Nurse Practitioner (FNP) certification exam is offered
by two certifying bodies: the American Academy of Nurse
Practitioners Certification Board (AANPCB) and the American
Nurses Credentialing Center (ANCC) . The official *FNP
Certification Intensive Review, Fifth Edition* by Maria T. Codina
Leik features over 1,200 practice questions with detailed rationales .
AANP FNP Exam Blueprint
| Domain | Percentage | Number of Items |
|--||--|
| Assessment | 32% | 43 |
| Diagnosis | 27% | 36 |
| Plan | 27% | 36 |
| Evaluation | 15% | 20 |
1
,| Total | 100% | 135 |
*The exam has 150 total questions (15 pretest/unscored) with a 3-
hour time limit* .
ANCC FNP Exam Blueprint
| Domain | Percentage |
|--||
| Assessment | 19% |
| Diagnosis | 17% |
| Planning | 19% |
| Implementation | 29% |
| Evaluation | 15% |
*The ANCC exam has 175 total questions (150 scored) with a 3.5-
hour time limit* .
2
,SECTION 1: CARDIOVASCULAR & HYPERTENSION
MANAGEMENT
Q1. A 72-year-old woman has been on hydrochlorothiazide 12.5 mg
for many years to control her Stage II hypertension. Her blood
pressure at this visit is 168/96. She is currently complaining of pain
on her right hip and on both knees. She has increased her dose of
ibuprofen from 400 mg TID to 800 mg TID. Which statement best
explains the effects of ibuprofen on her disease?
A) It increases the chances of adverse effects to her health
B) It inhibits the effect of renal prostaglandins and blunts the
effectiveness of the diuretic
C) It prolongs the therapeutic effects of hydrochlorothiazide
D) None of the statements are true
Answer: B
Rationale: NSAIDs inhibit the vasodilatory effects of
prostaglandins, predisposing the kidney to ischemia. NSAIDs and
diuretics can cause acute prerenal failure by decreasing renal blood
flow, which blunts the effectiveness of the diuretic and can lead to
worsening hypertension .
3
, Q2. A patient with hypertension and osteoarthritis is currently on
lisinopril 20 mg daily. She complains of a persistent, dry, non-
productive cough that has been present for the past 3 months. Which
is the most appropriate next step?
A) Reassure the patient that the cough will resolve
B) Add a cough suppressant
C) Discontinue lisinopril and switch to an angiotensin receptor
blocker (ARB)
D) Order a chest X-ray
Answer: C
Rationale: A persistent dry cough is a common side effect of ACE
inhibitors (lisinopril) due to bradykinin accumulation. Switching to
an ARB (which does not affect bradykinin) is appropriate.
4
Questions & Answers
Family Nurse Practitioner Board Exam Prep | Updated for AANP &
ANCC Blueprints
EXAM OVERVIEW
The Family Nurse Practitioner (FNP) certification exam is offered
by two certifying bodies: the American Academy of Nurse
Practitioners Certification Board (AANPCB) and the American
Nurses Credentialing Center (ANCC) . The official *FNP
Certification Intensive Review, Fifth Edition* by Maria T. Codina
Leik features over 1,200 practice questions with detailed rationales .
AANP FNP Exam Blueprint
| Domain | Percentage | Number of Items |
|--||--|
| Assessment | 32% | 43 |
| Diagnosis | 27% | 36 |
| Plan | 27% | 36 |
| Evaluation | 15% | 20 |
1
,| Total | 100% | 135 |
*The exam has 150 total questions (15 pretest/unscored) with a 3-
hour time limit* .
ANCC FNP Exam Blueprint
| Domain | Percentage |
|--||
| Assessment | 19% |
| Diagnosis | 17% |
| Planning | 19% |
| Implementation | 29% |
| Evaluation | 15% |
*The ANCC exam has 175 total questions (150 scored) with a 3.5-
hour time limit* .
2
,SECTION 1: CARDIOVASCULAR & HYPERTENSION
MANAGEMENT
Q1. A 72-year-old woman has been on hydrochlorothiazide 12.5 mg
for many years to control her Stage II hypertension. Her blood
pressure at this visit is 168/96. She is currently complaining of pain
on her right hip and on both knees. She has increased her dose of
ibuprofen from 400 mg TID to 800 mg TID. Which statement best
explains the effects of ibuprofen on her disease?
A) It increases the chances of adverse effects to her health
B) It inhibits the effect of renal prostaglandins and blunts the
effectiveness of the diuretic
C) It prolongs the therapeutic effects of hydrochlorothiazide
D) None of the statements are true
Answer: B
Rationale: NSAIDs inhibit the vasodilatory effects of
prostaglandins, predisposing the kidney to ischemia. NSAIDs and
diuretics can cause acute prerenal failure by decreasing renal blood
flow, which blunts the effectiveness of the diuretic and can lead to
worsening hypertension .
3
, Q2. A patient with hypertension and osteoarthritis is currently on
lisinopril 20 mg daily. She complains of a persistent, dry, non-
productive cough that has been present for the past 3 months. Which
is the most appropriate next step?
A) Reassure the patient that the cough will resolve
B) Add a cough suppressant
C) Discontinue lisinopril and switch to an angiotensin receptor
blocker (ARB)
D) Order a chest X-ray
Answer: C
Rationale: A persistent dry cough is a common side effect of ACE
inhibitors (lisinopril) due to bradykinin accumulation. Switching to
an ARB (which does not affect bradykinin) is appropriate.
4
