TEST BANK
Lippincott Illustrated Reviews: Pharmacology
KAREN WHALEN
Eighth, North American Edition
,Page I 2
,Pharmacology Illustrated Reviews 8th Edition Whalen
TEST BANK
Chapter 1:
Pharmacokinetics
MULTIPLE CHOICE
1. Which drugs will go through a pharmaceutic phase after it is administered?
a. Intramuscular cephalosporins
b. Intravenous vasopressors
c. Oral analgesics
d. Subcutaneous antiglyc
emics P..NS:C
When drugs are administered parenterally, there is no pharmaceutic phase, which
occurs when a
drug becomes as ol ution that can cross the biologic membrane.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF:
dm 3 TOP: NURSING PROCESS: Assessment
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
2. The nurse is preparing to administer an oral medication and wants to
ensure a rapid drug action. Which form of the medication will the nurse
administer?
a. Capsule
b. Enteric-co ated pill
c. Liquid suspension
d. Table
t
P..NS:
C
Liquid drugs are already in solution, which is the form necessary for absorption
in the GI tract. The other forms must disintegrate into small particles and then
dis solve before being absorbed.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF:
dm 3 TOP: NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
Page 1 of 507
, 3. The nurse is teaching a patient who will be discharged home with a prescription for an
enteric- coated tablet. Which statement by the patient indicates understanding of the
teaching?
a. I may crush the tablet and put it in applesauce to improve absorption.
b. I should consume acidic foods to enhance absorption of this medication.
c. I should expect a delay in onset of the drugs effects after taking the tablet.
d. I should take this medication with high-fat foods to improve its action. CORRECT ANSWER: C
Enteric-coated tablets resist disintegration in the acidic environment of the stomach and
disintegrate when they reach the small intestine. There is usually some delay in onset of
actions after taking these medications. Enteric-coated tablets should not be crushed or
chewed, which would alter the time and location of absorption. Acidic foods will not enhance
the absorption of the medication. The patient should not to eat high-fat food before
ingesting an enteric-coated tablet, because high-fat foods decrease the absorption rate.
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3 TOP: NURSING PROCESS: Nursing
Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
4. A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin must
be given by subcutaneous injection instead of by mouth. The nurse will explain that this
is because
a. absorption is diminished by the first-pass effects in the liver.
b. absorption is faster when insulin is given subcutaneously.
c. digestive enzymes in the gastrointestinal tract prevent absorption.
d. the oral form is less predictable with more adverse effects. CORRECT ANSWER: C
Insulin, growth hormones, and other protein-based drugs are destroyed in the small
intestine by digestive enzymes and must be given parenterally. Because insulin is
destroyed by digestive enzymes, it would not make it to the liver for metabolism with a
first-pass effect. Subcutaneous tissue has fewer blood vessels, so absorption is slower in
such tissue. Insulin is given subcutaneously because it is desirable to have it absorb slowly.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3 TOP: NURSING
PROCESS: Nursing Intervention: Patient Teaching
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
Page I 4
Lippincott Illustrated Reviews: Pharmacology
KAREN WHALEN
Eighth, North American Edition
,Page I 2
,Pharmacology Illustrated Reviews 8th Edition Whalen
TEST BANK
Chapter 1:
Pharmacokinetics
MULTIPLE CHOICE
1. Which drugs will go through a pharmaceutic phase after it is administered?
a. Intramuscular cephalosporins
b. Intravenous vasopressors
c. Oral analgesics
d. Subcutaneous antiglyc
emics P..NS:C
When drugs are administered parenterally, there is no pharmaceutic phase, which
occurs when a
drug becomes as ol ution that can cross the biologic membrane.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF:
dm 3 TOP: NURSING PROCESS: Assessment
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
2. The nurse is preparing to administer an oral medication and wants to
ensure a rapid drug action. Which form of the medication will the nurse
administer?
a. Capsule
b. Enteric-co ated pill
c. Liquid suspension
d. Table
t
P..NS:
C
Liquid drugs are already in solution, which is the form necessary for absorption
in the GI tract. The other forms must disintegrate into small particles and then
dis solve before being absorbed.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF:
dm 3 TOP: NURSING PROCESS: Nursing Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
Page 1 of 507
, 3. The nurse is teaching a patient who will be discharged home with a prescription for an
enteric- coated tablet. Which statement by the patient indicates understanding of the
teaching?
a. I may crush the tablet and put it in applesauce to improve absorption.
b. I should consume acidic foods to enhance absorption of this medication.
c. I should expect a delay in onset of the drugs effects after taking the tablet.
d. I should take this medication with high-fat foods to improve its action. CORRECT ANSWER: C
Enteric-coated tablets resist disintegration in the acidic environment of the stomach and
disintegrate when they reach the small intestine. There is usually some delay in onset of
actions after taking these medications. Enteric-coated tablets should not be crushed or
chewed, which would alter the time and location of absorption. Acidic foods will not enhance
the absorption of the medication. The patient should not to eat high-fat food before
ingesting an enteric-coated tablet, because high-fat foods decrease the absorption rate.
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3 TOP: NURSING PROCESS: Nursing
Intervention
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
4. A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin must
be given by subcutaneous injection instead of by mouth. The nurse will explain that this
is because
a. absorption is diminished by the first-pass effects in the liver.
b. absorption is faster when insulin is given subcutaneously.
c. digestive enzymes in the gastrointestinal tract prevent absorption.
d. the oral form is less predictable with more adverse effects. CORRECT ANSWER: C
Insulin, growth hormones, and other protein-based drugs are destroyed in the small
intestine by digestive enzymes and must be given parenterally. Because insulin is
destroyed by digestive enzymes, it would not make it to the liver for metabolism with a
first-pass effect. Subcutaneous tissue has fewer blood vessels, so absorption is slower in
such tissue. Insulin is given subcutaneously because it is desirable to have it absorb slowly.
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3 TOP: NURSING
PROCESS: Nursing Intervention: Patient Teaching
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
Page I 4
