NR 293 EXAM 1 -PHARMACOLOGY FOR NURSING
|ACTUAL QUESTIONS AND VERIFIED
ANSWERS|BRAND NEW 2026-2027
UPDATE|GRADED A+
Question 1
1. A patient must be treated immediately for acute organ transplant rejection. The nurse
anticipates that muromonab-CD3 (Orthoclone OKT3) will be ordered. What is the priority
assessment before beginning drug therapy with muromonab-CD3?
a. Serum potassium level
b. Fluid volume status
c. Electrocardiogram
d. Blood glucose level
CORRECT ANSWER
ANS: B
Assess fluid volume status because muromonab-CD3 is contraindicated in the presence of
fluid overload. The other options are incorrect.
DIF: COGNITIVE LEVEL: Applying (Application) REF: p. 777
TOP: NURSING PROCESS: Assessment
Question 2
2. A patient is about to undergo a kidney transplant. She will be given an
immunosuppressant drug before, during, and after surgery to minimize organ rejection.
During the preoperative teaching session, which information will the nurse include about
the medication therapy?
a. Several days before the surgery, the medication will be administered orally.
b. The oral doses need to be taken 1 hour before meals to maximize absorption.
1
@THE STUDY VAULT
,c. Mix the oral liquid with juice in a disposable Styrofoam cup just before administration.
d. Intramuscular injections of the medication will be needed for several days preceding
surgery.
CORRECT ANSWER
ANS: A
Several days before transplant surgery, immunosuppressant drugs need to be taken by the
oral route, if possible, to avoid intramuscular injections and the risk for infection caused by
the injections. Avoid Styrofoam containers because the medication may adhere to the side
of the container. These medications are taken with food to minimize gastrointestinal upset.
DIF: COGNITIVE LEVEL: Applying (Application) REF: p. 778
TOP: NURSING PROCESS: Implementation
Question 3
3. A patient has an order for cyclosporine (Sandimmune). The nurse finds that
cyclosporine-modified (Neoral) is available in the automated medication cabinet. Which
action by the nurse is correct?
a. Hold the dose until the prescriber makes rounds.
b. Give the cyclosporine-modified drug.
c. Double-check the order, and then give the cyclosporine-modified drug.
d. Notify the pharmacy to obtain the Sandimmune form of the drug.
CORRECT ANSWER
ANS: D
The nurse must double-check the formulation before giving cyclosporine. Cyclosporine-
modified products (such as Neoral or Gengraf) are interchangeable with each other but are
not interchangeable with Sandimmune. In this case, the nurse must obtain the
Sandimmune form of the drug from the pharmacy. The other options are incorrect.
DIF: COGNITIVE LEVEL: Analyzing (Analysis) REF: p. 778
2
@THE STUDY VAULT
, TOP: NURSING PROCESS: Implementation
Question 4
4. The nurse is preparing to administer an injection of monoclonal antibodies. Which
additional drug will the nurse administer to minimize adverse reactions to the monoclonal
antibodies?
a. A nonsteroidal anti-inflammatory drug
b. A benzodiazepine
c. An opioid pain reliever
d. A corticosteroid
CORRECT ANSWER
ANS: D
The monoclonal antibodies basiliximab and daclizimab have a tendency to cause the
allergy-like reaction known as cytokine release syndrome, which can be severe and even
involve anaphylaxis. In an effort to avoid or alleviate this problem, it is recommended that
an injection of a corticosteroid, such as methylprednisolone, be administered before the
injection of monoclonal antibodies.
DIF: COGNITIVE LEVEL: Applying (Application) REF: p. 773
TOP: NURSING PROCESS: Implementation
Question 5
5. When administering cyclosporine, the nurse notes that allopurinol is also ordered for
the patient. What is a potential result of this drug interaction?
a. Reduced adverse effects of the cyclosporine
b. Increased levels of cyclosporine and toxicity
c. Reduced uric acid levels
3
@THE STUDY VAULT
, d. Reduced nephrotoxic effects of cyclosporine
CORRECT ANSWER
ANS: B
The allopurinol may cause increased levels of cyclosporine, and toxicity may result. The
other options are incorrect.
DIF: COGNITIVE LEVEL: Applying (Application) REF: p. 774
TOP: NURSING PROCESS: Planning
Question 6
6. The nurse is monitoring a patient who is receiving muromonab-CD3 (Orthoclone OKT3)
after an organ transplant. Which effect is possible with muromonab-CD3 therapy?
a. Chest pain
b. Hypotension
c. Confusion
d. Dysuria
CORRECT ANSWER
ANS: A
Muromonab-CD3 may cause chest pain, fever, chills, tremor, gastrointestinal disturbances
(nausea, vomiting, diarrhea), and other effects as noted in Table 48-2. The other options
are incorrect.
DIF: COGNITIVE LEVEL: Applying (Application) REF: p. 773
TOP: NURSING PROCESS: Evaluation
Question 7
4
@THE STUDY VAULT
|ACTUAL QUESTIONS AND VERIFIED
ANSWERS|BRAND NEW 2026-2027
UPDATE|GRADED A+
Question 1
1. A patient must be treated immediately for acute organ transplant rejection. The nurse
anticipates that muromonab-CD3 (Orthoclone OKT3) will be ordered. What is the priority
assessment before beginning drug therapy with muromonab-CD3?
a. Serum potassium level
b. Fluid volume status
c. Electrocardiogram
d. Blood glucose level
CORRECT ANSWER
ANS: B
Assess fluid volume status because muromonab-CD3 is contraindicated in the presence of
fluid overload. The other options are incorrect.
DIF: COGNITIVE LEVEL: Applying (Application) REF: p. 777
TOP: NURSING PROCESS: Assessment
Question 2
2. A patient is about to undergo a kidney transplant. She will be given an
immunosuppressant drug before, during, and after surgery to minimize organ rejection.
During the preoperative teaching session, which information will the nurse include about
the medication therapy?
a. Several days before the surgery, the medication will be administered orally.
b. The oral doses need to be taken 1 hour before meals to maximize absorption.
1
@THE STUDY VAULT
,c. Mix the oral liquid with juice in a disposable Styrofoam cup just before administration.
d. Intramuscular injections of the medication will be needed for several days preceding
surgery.
CORRECT ANSWER
ANS: A
Several days before transplant surgery, immunosuppressant drugs need to be taken by the
oral route, if possible, to avoid intramuscular injections and the risk for infection caused by
the injections. Avoid Styrofoam containers because the medication may adhere to the side
of the container. These medications are taken with food to minimize gastrointestinal upset.
DIF: COGNITIVE LEVEL: Applying (Application) REF: p. 778
TOP: NURSING PROCESS: Implementation
Question 3
3. A patient has an order for cyclosporine (Sandimmune). The nurse finds that
cyclosporine-modified (Neoral) is available in the automated medication cabinet. Which
action by the nurse is correct?
a. Hold the dose until the prescriber makes rounds.
b. Give the cyclosporine-modified drug.
c. Double-check the order, and then give the cyclosporine-modified drug.
d. Notify the pharmacy to obtain the Sandimmune form of the drug.
CORRECT ANSWER
ANS: D
The nurse must double-check the formulation before giving cyclosporine. Cyclosporine-
modified products (such as Neoral or Gengraf) are interchangeable with each other but are
not interchangeable with Sandimmune. In this case, the nurse must obtain the
Sandimmune form of the drug from the pharmacy. The other options are incorrect.
DIF: COGNITIVE LEVEL: Analyzing (Analysis) REF: p. 778
2
@THE STUDY VAULT
, TOP: NURSING PROCESS: Implementation
Question 4
4. The nurse is preparing to administer an injection of monoclonal antibodies. Which
additional drug will the nurse administer to minimize adverse reactions to the monoclonal
antibodies?
a. A nonsteroidal anti-inflammatory drug
b. A benzodiazepine
c. An opioid pain reliever
d. A corticosteroid
CORRECT ANSWER
ANS: D
The monoclonal antibodies basiliximab and daclizimab have a tendency to cause the
allergy-like reaction known as cytokine release syndrome, which can be severe and even
involve anaphylaxis. In an effort to avoid or alleviate this problem, it is recommended that
an injection of a corticosteroid, such as methylprednisolone, be administered before the
injection of monoclonal antibodies.
DIF: COGNITIVE LEVEL: Applying (Application) REF: p. 773
TOP: NURSING PROCESS: Implementation
Question 5
5. When administering cyclosporine, the nurse notes that allopurinol is also ordered for
the patient. What is a potential result of this drug interaction?
a. Reduced adverse effects of the cyclosporine
b. Increased levels of cyclosporine and toxicity
c. Reduced uric acid levels
3
@THE STUDY VAULT
, d. Reduced nephrotoxic effects of cyclosporine
CORRECT ANSWER
ANS: B
The allopurinol may cause increased levels of cyclosporine, and toxicity may result. The
other options are incorrect.
DIF: COGNITIVE LEVEL: Applying (Application) REF: p. 774
TOP: NURSING PROCESS: Planning
Question 6
6. The nurse is monitoring a patient who is receiving muromonab-CD3 (Orthoclone OKT3)
after an organ transplant. Which effect is possible with muromonab-CD3 therapy?
a. Chest pain
b. Hypotension
c. Confusion
d. Dysuria
CORRECT ANSWER
ANS: A
Muromonab-CD3 may cause chest pain, fever, chills, tremor, gastrointestinal disturbances
(nausea, vomiting, diarrhea), and other effects as noted in Table 48-2. The other options
are incorrect.
DIF: COGNITIVE LEVEL: Applying (Application) REF: p. 773
TOP: NURSING PROCESS: Evaluation
Question 7
4
@THE STUDY VAULT
