and Clinical Diagnosis in
Primary Care 6th Edition Test
Bank – Questions, Answers &
Rationales 2026/2027
1. A 58-year-old male presents with crushing substernal
chest pain radiating to the left arm. Which finding is most
concerning for acute coronary syndrome?
A. Pain worsened by movement
B. Pain relieved by antacids
C. Diaphoresis and nausea
D. Localized chest wall tenderness
Answer: C. Diaphoresis and nausea
Rationale: Diaphoresis and nausea commonly accompany acute
coronary syndrome and increase suspicion for myocardial
ischemia.
2. During a cardiovascular examination, the nurse
practitioner hears a high-pitched blowing sound
immediately after S2. This finding is most consistent with:
A. Mitral stenosis
B. Aortic regurgitation
,C. Tricuspid stenosis
D. Pulmonic stenosis
Answer: B. Aortic regurgitation
Rationale: Aortic regurgitation typically produces a high-
pitched early diastolic decrescendo murmur heard best along
the left sternal border.
3. Which symptom is most characteristic of
hyperthyroidism?
A. Weight gain
B. Cold intolerance
C. Bradycardia
D. Heat intolerance
Answer: D. Heat intolerance
Rationale: Increased metabolic activity in hyperthyroidism
commonly causes heat intolerance, weight loss, and
tachycardia.
4. A patient presents with right lower quadrant abdominal
pain, fever, and nausea. Which diagnosis should be
considered first?
A. Cholecystitis
B. Appendicitis
C. Gastritis
D. Pancreatitis
Answer: B. Appendicitis
,Rationale: Right lower quadrant pain with fever and nausea is a
classic presentation of acute appendicitis.
5. Which assessment finding is most suggestive of bacterial
meningitis?
A. Productive cough
B. Polyuria
C. Nuchal rigidity
D. Peripheral edema
Answer: C. Nuchal rigidity
Rationale: Neck stiffness, fever, and headache are hallmark
findings associated with meningitis.
6. A patient reports progressive shortness of breath and
bilateral ankle edema. Which condition is most likely?
A. Heart failure
B. Peptic ulcer disease
C. Migraine headache
D. Otitis media
Answer: A. Heart failure
Rationale: Dyspnea and peripheral edema commonly occur due
to fluid overload associated with heart failure.
7. Which laboratory value is most useful in evaluating long-
term glycemic control?
A. Random glucose
B. Fasting insulin
, C. Hemoglobin A1C
D. Serum sodium
Answer: C. Hemoglobin A1C
Rationale: Hemoglobin A1C reflects average blood glucose
levels over approximately three months.
8. The presence of rebound tenderness during abdominal
examination suggests:
A. Peritoneal irritation
B. Dehydration
C. Liver disease
D. Constipation
Answer: A. Peritoneal irritation
Rationale: Rebound tenderness is commonly associated with
inflammation of the peritoneum.
9. Which finding is most concerning during a skin
assessment?
A. Symmetric freckles
B. Uniformly pigmented nevus
C. Irregular pigmented lesion with color variation
D. Small skin tag
Answer: C. Irregular pigmented lesion with color variation
Rationale: Asymmetry, border irregularity, color variation, and
enlargement may indicate melanoma.