NR566 FINAL Exam Review Question and correct
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ADV PHARMACOLOGY Final EXAM/Nr 566 Advanced
pharmacology for care of the family Chamberlain
University
Exam Coverage: Weeks 5–8 (Eyes, Ears, Nose & Skin; Mental Health; CNS Disorders;
Health Promotion & Weight Loss)
Note: This is an original practice exam created for study purposes. Explanations appear
in italics after each question.
SECTION 1: PHARMACOTHERAPY FOR EYES, EARS, NOSE &
SKIN
1. Which medication is a prostaglandin analog used for open-angle glaucoma that
increases aqueous humor outflow?
A) Timolol
B) Latanoprost
C) Pilocarpine
D) Dorzolamide
Answer: B
Latanoprost is a prostaglandin analog that increases aqueous humor outflow by relaxing
the ciliary muscle, reducing intraocular pressure in open-angle glaucoma .
,2. A patient on latanoprost notices darkening of the iris. What should the nurse
practitioner advise?
A) This is a sign of toxicity and requires immediate discontinuation
B) This is a common, non-dangerous cosmetic effect that may be permanent
C) This indicates the medication is not working
D) This will resolve within one week
Answer: B
Prostaglandin analogs like latanoprost commonly cause gradual darkening of the iris and
eyelid. This cosmetic change is common but not harmful, though it may be permanent .
3. Which ophthalmic beta-blocker is safest for a patient with COPD and glaucoma?
A) Timolol
B) Betaxolol
C) Latanoprost
D) Brimonidine
Answer: B
Betaxolol is a cardioselective beta-1 blocker that is safer for patients with COPD/asthma
compared to timolol, which can cause bronchospasm .
4. What is the primary mechanism of action of timolol in glaucoma treatment?
A) Increases aqueous humor outflow
B) Decreases aqueous humor production
C) Constricts the pupil
D) Relaxes the ciliary muscle
Answer: B
Timolol is a beta-blocker that decreases aqueous humor production by the ciliary body,
reducing intraocular pressure.
,5. A patient using phenylephrine nasal spray around the clock for 10 days reports
worsening congestion. What is the most likely explanation?
A) Allergic reaction to the preservative
B) Rebound congestion from prolonged topical decongestant use
C) Development of bacterial sinusitis
D) Superimposed allergic conjunctivitis
Answer: B
Extended use of topical adrenergic nasal decongestants beyond a few days can cause
rhinitis medicamentosa, characterized by rebound nasal congestion .
6. Which medication is a mast-cell stabilizer used for allergic conjunctivitis with a
delayed onset of action?
A) Naphazoline
B) Cromolyn
C) Olopatadine
D) Ketorolac
Answer: B
Cromolyn is a mast-cell stabilizer that prevents release of inflammatory mediators. Relief
may take several days because it prevents mediator release rather than blocking
histamine already present .
7. What is the primary treatment for acute otitis externa?
A) Oral antibiotics
B) Topical antimicrobials
C) IV antibiotics
D) Surgery
, Answer: B
Topical antimicrobials are the primary treatment for acute otitis externa. Oral antibiotics
are reserved for severe cases or when topical therapy fails.
8. Which otic regimen is safe for a patient with a perforated tympanic membrane?
A) Neomycin/polymyxin B/hydrocortisone
B) Ofloxacin 0.3% otic solution
C) Gentamicin otic drops
D) Acetic acid 2% otic solution
Answer: B
Fluoroquinolone otic solutions such as ofloxacin are recommended and safe in the
presence of TM perforation, whereas aminoglycoside combinations like
neomycin/polymyxin B/hydrocortisone should be avoided due to ototoxicity risk .
9. What is the first-line treatment for acute otitis media in a child without
penicillin allergy?
A) Azithromycin
B) Amoxicillin
C) Cephalexin
D) Clindamycin
Answer: B
Amoxicillin is first-line for acute otitis media in children without penicillin allergy due to its
efficacy against common pathogens.
10. According to guidelines, what is an appropriate initial management strategy
for a healthy child over 6 months old with mild symptoms of acute otitis media?
A) Immediate antibiotics
B) Watchful waiting with analgesics