NR-293
Pharmacology for Nursing Practice
EXAM 1 PRACTICE
80 Multiple-Choice Questions &
Correct Answers with Detailed Rationales & Clinical Application
2026/2027 Study Edition
WHAT’S INSIDE
80 Multiple-Choice Questions & Correct Answers
Detailed Rationales
Clinical Application
COURSE-ALIGNED STUDY RESOURCE
For independent exam preparation and concept review
1
,Exam 1 Practice Contents
Domain Questions
Foundations of Pharmacology 20
Medication Safety 15
Administration and Routes 10
Dosage Calculations 10
Clinical Application 25
2
, Foundations of Pharmacology
Question 1. A nurse explains that pharmacokinetics describes which process?
A. How a medication produces its effect at receptor sites
B. How the body absorbs, distributes, metabolizes, and excretes a medication
C. How genetic variation changes a medication's target receptor
D. How medications are classified by therapeutic use
Correct Answer: B. How the body absorbs, distributes, metabolizes, and excretes a
medication
Rationale: Pharmacokinetics is what the body does to a drug: absorption, distribution,
metabolism, and excretion (ADME). Pharmacodynamics describes what the drug does to the
body, including receptor interactions and resulting effects.
Question 2. Which statement best describes pharmacodynamics?
A. The movement of a drug through the body
B. The study of medication cost and availability
C. The biochemical and physiologic effects of a drug on the body
D. The process by which the kidneys eliminate a drug
Correct Answer: C. The biochemical and physiologic effects of a drug on the body
Rationale: Pharmacodynamics concerns a medication's effects on the body, including receptor
binding, dose-response relationships, and therapeutic or adverse effects. Movement through
the body is pharmacokinetics.
Question 3. A medication taken orally undergoes extensive first-pass metabolism. What effect
should the nurse expect?
A. A larger proportion of the dose reaches systemic circulation unchanged
B. The medication bypasses the liver before reaching circulation
C. Bioavailability may be reduced before the drug reaches systemic circulation
D. Renal excretion is completely prevented
Correct Answer: C. Bioavailability may be reduced before the drug reaches systemic
circulation
3
Pharmacology for Nursing Practice
EXAM 1 PRACTICE
80 Multiple-Choice Questions &
Correct Answers with Detailed Rationales & Clinical Application
2026/2027 Study Edition
WHAT’S INSIDE
80 Multiple-Choice Questions & Correct Answers
Detailed Rationales
Clinical Application
COURSE-ALIGNED STUDY RESOURCE
For independent exam preparation and concept review
1
,Exam 1 Practice Contents
Domain Questions
Foundations of Pharmacology 20
Medication Safety 15
Administration and Routes 10
Dosage Calculations 10
Clinical Application 25
2
, Foundations of Pharmacology
Question 1. A nurse explains that pharmacokinetics describes which process?
A. How a medication produces its effect at receptor sites
B. How the body absorbs, distributes, metabolizes, and excretes a medication
C. How genetic variation changes a medication's target receptor
D. How medications are classified by therapeutic use
Correct Answer: B. How the body absorbs, distributes, metabolizes, and excretes a
medication
Rationale: Pharmacokinetics is what the body does to a drug: absorption, distribution,
metabolism, and excretion (ADME). Pharmacodynamics describes what the drug does to the
body, including receptor interactions and resulting effects.
Question 2. Which statement best describes pharmacodynamics?
A. The movement of a drug through the body
B. The study of medication cost and availability
C. The biochemical and physiologic effects of a drug on the body
D. The process by which the kidneys eliminate a drug
Correct Answer: C. The biochemical and physiologic effects of a drug on the body
Rationale: Pharmacodynamics concerns a medication's effects on the body, including receptor
binding, dose-response relationships, and therapeutic or adverse effects. Movement through
the body is pharmacokinetics.
Question 3. A medication taken orally undergoes extensive first-pass metabolism. What effect
should the nurse expect?
A. A larger proportion of the dose reaches systemic circulation unchanged
B. The medication bypasses the liver before reaching circulation
C. Bioavailability may be reduced before the drug reaches systemic circulation
D. Renal excretion is completely prevented
Correct Answer: C. Bioavailability may be reduced before the drug reaches systemic
circulation
3
