NSG 152 INFECTION TEST 2026/2027 | INFECTION CONTROL NURSING QUESTIONS & ANSW…
P R O F E S S I O N A L P R A C T I C E M AT E R I A L S
NSG 152 Infection Test
2026/2027 | Infection
Control Nursing Questions
& Answers | Comprehensive
Review (Rationales)
Verified Answers Exam Ready With Rationales 85 QUESTIONS
DOCUMENT OVERVIEW
This comprehensive review document provides 85 infection control nursing questions,
complete with correct answers and detailed rationales, often accompanied by diagrams. It
is an invaluable resource for students to thoroughly study and review infection control
principles. This material is perfectly suited for exam preparation and certification review,
offering a complete learning package.
TOPICS
Antimicrobial Agents Q1–Q20
Infection Fundamentals Q21–Q32
Cellular Processes & Diagnostics Q33–Q48
Respiratory & Ear Infections Q49–Q63
Meningitis & Fever Management Q64–Q78
Healthcare-Associated Infections & Monitoring Q79–Q85
Page 1
, E XA M Q U EST I O N S
Q1 QUESTION 1 OF 85
Antibiotics (-cillin)
RESPONSE
• Penicillin G and V
(natural, first gen)
• Amoxicillin, ampicillin, carbenicillin (2nd gen, more B. spectrum)
• Methicillin, nafcillin, cloxacillin (effective against some penicillin -resistant organisms
• Carbenicillin, piperacillin, ticaricillin (extended-spectrum)
RATIONALE
The classification of penicillins is based on their spectrum of activity and generation. Natural
penicillins like Penicillin G and V are first-generation agents. Subsequent generations, such as the
second-generation penicillins (amoxicillin, ampicillin), exhibit broader bacterial coverage, while
others are designed to overcome resistance or offer extended-spectrum activity.
Q2 QUESTION 2 OF 85
Antibiotics (-cillin): Side Effects
RESPONSE
diarrhea, epigastric distress, nausea, vomiting, rash
RATIONALE
Penicillin-class antibiotics can disrupt the normal gastrointestinal flora, leading to gastrointestinal
disturbances. This disruption commonly manifests as nausea, vomiting, epigastric distress, and
diarrhea. Additionally, hypersensitivity reactions can present as a rash.
Q3 QUESTION 3 OF 85
Antibiotics (-cillin): Adverse Effects
Page 2
, RESPONSE
Allergies, Anaphylaxis, hypersensitivity, superinfection, CDAD (C.Diff Associated Disease)
RATIONALE
Penicillin-class antibiotics can trigger immune-mediated hypersensitivity reactions, ranging from
mild rashes to severe anaphylaxis. Additionally, their broad-spectrum activity disrupts normal flora,
leading to opportunistic infections like Clostridioides difficile-associated disease and
superinfections.
Q4 QUESTION 4 OF 85
Antibiotics (-cillin): Pt Education
RESPONSE
• Patient should complete entire course of antibiotic
• Report any signs of superinfection to HCP ( black growth on tongue, vaginal itching, loose
stools)
• Report onset of diarrhea
• May interfere with oral contraceptives
• Patients with Penicillin allergy should wear bracelet; advise HCP
RATIONALE
Completing the full antibiotic course eradicates pathogens and prevents resistance development.
Patients must report adverse effects like superinfections (e.g., oral thrush, C. diff diarrhea) or
contraceptive interactions to their healthcare provider. Those with penicillin allergies should wear
identification to ensure safe future treatment.
Q5 QUESTION 5 OF 85
Antibiotics (-micin, -mycin)
RESPONSE
• Gentamicin
• Tobramycin
• Neomycin
Page 3
, RATIONALE
The suffix "-micin" or "-mycin" typically denotes a class of antibiotics derived from *Streptomyces*
species, which are aminoglycosides. These agents are bactericidal and primarily used for serious
Gram-negative infections by inhibiting bacterial protein synthesis. Examples include Gentamicin,
Tobramycin, and Neomycin.
Q6 QUESTION 6 OF 85
Antibiotics (-micin, -mycin): Side Effects
RESPONSE
Ataxia, ototoxicity (vestibular and cochlear), nephrotoxicity, muscle paralysis (high parenteral
doses)
RATIONALE
Aminoglycoside antibiotics, characterized by suffixes like -micin and -mycin, are associated with
specific dose-dependent toxicities. These include neurological effects such as ataxia and muscle
paralysis, as well as damage to the inner ear (ototoxicity) and kidneys (nephrotoxicity). These
adverse effects necessitate careful monitoring of drug levels and patient symptoms.
Q7 QUESTION 7 OF 85
Antibiotics (-micin, -mycin): Adverse Effects
RESPONSE
Been shown to cross the placenta
RATIONALE
Certain antibiotics, particularly those ending in -micin or -mycin, pose a risk due to their
pharmacokinetic properties. These agents have demonstrated the capacity to traverse the
placental barrier. This placental transfer necessitates careful consideration during pregnancy to
mitigate potential teratogenic effects on the fetus.
Q8 QUESTION 8 OF 85
Antibiotics (-micin, -mycin): Pt Education
Page 4
P R O F E S S I O N A L P R A C T I C E M AT E R I A L S
NSG 152 Infection Test
2026/2027 | Infection
Control Nursing Questions
& Answers | Comprehensive
Review (Rationales)
Verified Answers Exam Ready With Rationales 85 QUESTIONS
DOCUMENT OVERVIEW
This comprehensive review document provides 85 infection control nursing questions,
complete with correct answers and detailed rationales, often accompanied by diagrams. It
is an invaluable resource for students to thoroughly study and review infection control
principles. This material is perfectly suited for exam preparation and certification review,
offering a complete learning package.
TOPICS
Antimicrobial Agents Q1–Q20
Infection Fundamentals Q21–Q32
Cellular Processes & Diagnostics Q33–Q48
Respiratory & Ear Infections Q49–Q63
Meningitis & Fever Management Q64–Q78
Healthcare-Associated Infections & Monitoring Q79–Q85
Page 1
, E XA M Q U EST I O N S
Q1 QUESTION 1 OF 85
Antibiotics (-cillin)
RESPONSE
• Penicillin G and V
(natural, first gen)
• Amoxicillin, ampicillin, carbenicillin (2nd gen, more B. spectrum)
• Methicillin, nafcillin, cloxacillin (effective against some penicillin -resistant organisms
• Carbenicillin, piperacillin, ticaricillin (extended-spectrum)
RATIONALE
The classification of penicillins is based on their spectrum of activity and generation. Natural
penicillins like Penicillin G and V are first-generation agents. Subsequent generations, such as the
second-generation penicillins (amoxicillin, ampicillin), exhibit broader bacterial coverage, while
others are designed to overcome resistance or offer extended-spectrum activity.
Q2 QUESTION 2 OF 85
Antibiotics (-cillin): Side Effects
RESPONSE
diarrhea, epigastric distress, nausea, vomiting, rash
RATIONALE
Penicillin-class antibiotics can disrupt the normal gastrointestinal flora, leading to gastrointestinal
disturbances. This disruption commonly manifests as nausea, vomiting, epigastric distress, and
diarrhea. Additionally, hypersensitivity reactions can present as a rash.
Q3 QUESTION 3 OF 85
Antibiotics (-cillin): Adverse Effects
Page 2
, RESPONSE
Allergies, Anaphylaxis, hypersensitivity, superinfection, CDAD (C.Diff Associated Disease)
RATIONALE
Penicillin-class antibiotics can trigger immune-mediated hypersensitivity reactions, ranging from
mild rashes to severe anaphylaxis. Additionally, their broad-spectrum activity disrupts normal flora,
leading to opportunistic infections like Clostridioides difficile-associated disease and
superinfections.
Q4 QUESTION 4 OF 85
Antibiotics (-cillin): Pt Education
RESPONSE
• Patient should complete entire course of antibiotic
• Report any signs of superinfection to HCP ( black growth on tongue, vaginal itching, loose
stools)
• Report onset of diarrhea
• May interfere with oral contraceptives
• Patients with Penicillin allergy should wear bracelet; advise HCP
RATIONALE
Completing the full antibiotic course eradicates pathogens and prevents resistance development.
Patients must report adverse effects like superinfections (e.g., oral thrush, C. diff diarrhea) or
contraceptive interactions to their healthcare provider. Those with penicillin allergies should wear
identification to ensure safe future treatment.
Q5 QUESTION 5 OF 85
Antibiotics (-micin, -mycin)
RESPONSE
• Gentamicin
• Tobramycin
• Neomycin
Page 3
, RATIONALE
The suffix "-micin" or "-mycin" typically denotes a class of antibiotics derived from *Streptomyces*
species, which are aminoglycosides. These agents are bactericidal and primarily used for serious
Gram-negative infections by inhibiting bacterial protein synthesis. Examples include Gentamicin,
Tobramycin, and Neomycin.
Q6 QUESTION 6 OF 85
Antibiotics (-micin, -mycin): Side Effects
RESPONSE
Ataxia, ototoxicity (vestibular and cochlear), nephrotoxicity, muscle paralysis (high parenteral
doses)
RATIONALE
Aminoglycoside antibiotics, characterized by suffixes like -micin and -mycin, are associated with
specific dose-dependent toxicities. These include neurological effects such as ataxia and muscle
paralysis, as well as damage to the inner ear (ototoxicity) and kidneys (nephrotoxicity). These
adverse effects necessitate careful monitoring of drug levels and patient symptoms.
Q7 QUESTION 7 OF 85
Antibiotics (-micin, -mycin): Adverse Effects
RESPONSE
Been shown to cross the placenta
RATIONALE
Certain antibiotics, particularly those ending in -micin or -mycin, pose a risk due to their
pharmacokinetic properties. These agents have demonstrated the capacity to traverse the
placental barrier. This placental transfer necessitates careful consideration during pregnancy to
mitigate potential teratogenic effects on the fetus.
Q8 QUESTION 8 OF 85
Antibiotics (-micin, -mycin): Pt Education
Page 4
