NUR 622 (Adult_Gero Acute) MOD #1, Part 1 (Allergy_Immunology) Questions with CORRECT
Answers (Grade A+)
Question 1:
hypersensitivity reaction when an allergen binds to IgE on mast cells and basophils -immediate
release of histamine/prostaglandins and inflammatory mediators -symptoms are immediate
Answer:
type 1: immediate IgE mediated
Question 2:
examples of type 1 hypersensitivity reactions
Answer:
ANAPHYLAXIS, ASTHMA, hives, angioedema, allergic rhinitis
Question 3:
common triggers of type 1 hypersensitivity reactions
Answer:
foods, environmental allergens, insect venoms, medications (PCN), latex
Question 4:
hypersensitivity reaction when IgG or IgM antibodies bind to cell surfaces -leads to tissue damage
and cell death by complement activation and cytotoxicity -reactions develop over hours to days
Answer:
type 2: antibody mediated cytotoxic
Question 5:
examples of type 2 hypersensitivity reactions
Answer:
-autoimmune or drug induced hemolytic anemia -hemolytic transfusion reactions -ITP -hemolytic
disease of newborn -Grave's disease -MG -Goodpasture syndrome (affects kidneys and lungs)
-rheumatic fever
Question 6:
, hypersensitivity reaction caused by IgG antibodies binding with soluble antigens, causing
complexes that deposit in tissues and joints -symptoms usually occur 1-3 weeks after exposure
Answer:
type 3: immune-complex mediated
Question 7:
examples of type 3 hypersensitivity reactions
Answer:
-serum sickness (fever, joint pain, rash) -SLE -RA -post strep glomerulonephritis
Question 8:
hypersensitivity reaction caused by an antigen triggering T-cell activation -only reaction that does
not include antibodies -symptoms presents 48-72 hours after exposure to antigen (delayed)
Answer:
type 4: delayed T-cell Mediated
Question 9:
examples of type 4 hypersensitivity reactions
Answer:
-contact dermatitis (poison ivy, nickel) -SJS/TENS -PPD reaction -transplant rejection
Question 10:
Pneumonic for hypersensitivity reactions
Answer:
ACID A= allergic, IgE mediated C = cytotoxic and cell mediated I = immune complex D = delayed T
cell mediated
Question 11:
Patient comes in with anaphylaxis after eating shrimp 20 min prior, what should you ask the
patient?
Answer:
Have you ever had a reaction to shellfish before?
Answers (Grade A+)
Question 1:
hypersensitivity reaction when an allergen binds to IgE on mast cells and basophils -immediate
release of histamine/prostaglandins and inflammatory mediators -symptoms are immediate
Answer:
type 1: immediate IgE mediated
Question 2:
examples of type 1 hypersensitivity reactions
Answer:
ANAPHYLAXIS, ASTHMA, hives, angioedema, allergic rhinitis
Question 3:
common triggers of type 1 hypersensitivity reactions
Answer:
foods, environmental allergens, insect venoms, medications (PCN), latex
Question 4:
hypersensitivity reaction when IgG or IgM antibodies bind to cell surfaces -leads to tissue damage
and cell death by complement activation and cytotoxicity -reactions develop over hours to days
Answer:
type 2: antibody mediated cytotoxic
Question 5:
examples of type 2 hypersensitivity reactions
Answer:
-autoimmune or drug induced hemolytic anemia -hemolytic transfusion reactions -ITP -hemolytic
disease of newborn -Grave's disease -MG -Goodpasture syndrome (affects kidneys and lungs)
-rheumatic fever
Question 6:
, hypersensitivity reaction caused by IgG antibodies binding with soluble antigens, causing
complexes that deposit in tissues and joints -symptoms usually occur 1-3 weeks after exposure
Answer:
type 3: immune-complex mediated
Question 7:
examples of type 3 hypersensitivity reactions
Answer:
-serum sickness (fever, joint pain, rash) -SLE -RA -post strep glomerulonephritis
Question 8:
hypersensitivity reaction caused by an antigen triggering T-cell activation -only reaction that does
not include antibodies -symptoms presents 48-72 hours after exposure to antigen (delayed)
Answer:
type 4: delayed T-cell Mediated
Question 9:
examples of type 4 hypersensitivity reactions
Answer:
-contact dermatitis (poison ivy, nickel) -SJS/TENS -PPD reaction -transplant rejection
Question 10:
Pneumonic for hypersensitivity reactions
Answer:
ACID A= allergic, IgE mediated C = cytotoxic and cell mediated I = immune complex D = delayed T
cell mediated
Question 11:
Patient comes in with anaphylaxis after eating shrimp 20 min prior, what should you ask the
patient?
Answer:
Have you ever had a reaction to shellfish before?
