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Test Bank for Pharmacology for Pharmacy Technicians 4th Edition by Kathy Moscou

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Test Bank for Pharmacology for Pharmacy Technicians 4th Edition by Kathy Moscou

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Test Bank - Chapter 01

1. By which of the following routes are drugs administered directly into the bloodstream? [Multiple Choice]

a. Enteral

b. Transdermal

c. Transmucosal

d. Intravenous ✔

ANS: D

Parenteral drugs are injected or infused (slowly injected) directly into a blood vessel, muscle, skin, or joint; IV, IM,
subcutaneous, and intrathecal are common routes. Enteral (oral) route requires going through the GI system,
transdermal (through the dermis) route requires lipid solubility, and transmucosal (through a membrane) route
requires crossing a mucous membrane, which are not directly into the bloodstream.

Parenteral drugs are injected or infused (slowly injected) directly into a blood vessel, muscle, skin, or joint; IV, IM,
subcutaneous, and intrathecal are common routes. Enteral (oral) route requires going through the GI system,
transdermal (through the dermis) route requires lipid solubility, and transmucosal (through a membrane) route
requires crossing a mucous membrane, which are not directly into the bloodstream.

2. Fentanyl is used as a _____. [Multiple Choice]

a. synthetic anesthetic

b. synthetic analgesic ✔

c. natural analgesic

d. natural anesthetic

ANS: B

Fentanyl is a synthetically manufactured analgesic, made by chemical synthesis to mimic the natural drug opium
for the relief of pain. Synthetic anesthetics are chemically synthesized for the lack of response to pain. Natural
products are found in nature typically derived from plants, animals, or minerals; fentanyl is not a natural product
and therefore would not be used as a natural analgesic.

Fentanyl is a synthetically manufactured analgesic, made by chemical synthesis to mimic the natural drug opium
for the relief of pain. Synthetic anesthetics are chemically synthesized for the lack of response to pain. Natural
products are found in nature typically derived from plants, animals, or minerals; fentanyl is not a natural product
and therefore would not be used as a natural analgesic.

3. To help reduce nausea, the natural drug _____ can be used. [Multiple Choice]

,a. digitalis

b. peppermint ✔

c. caffeine

d. quinine

ANS: B

Some common beverages and foods are natural drugs. Coffee and tea contain the drug caffeine. Ginger and
peppermint contain ingredients that can reduce nausea. While the other options are natural drugs, they are not
used as a drug to reduce nausea.

Some common beverages and foods are natural drugs. Coffee and tea contain the drug caffeine. Ginger and
peppermint contain ingredients that can reduce nausea. While the other options are natural drugs, they are not
used as a drug to reduce nausea.

4. Which of the following options results in an untrue statement about pharmacy technicians? Pharmacy
technicians who possess a good knowledge of pharmacology understand the importance of _____. [Multiple Choice]

a. drug interactions

b. therapeutic duplication

c. lab values ✔

d. excessive dose alerts

ANS: C

Knowledge of pharmacology facilitates selection of warning labels for drugs dispensed. Pharmacy technicians who
possess a good knowledge of pharmacology understand the importance of recognizing drug interactions,
therapeutic duplication, and excessive dose alerts screened by the computer. Knowing and interpreting lab values
is beyond the scope of a pharmacy technician and is left to the professional judgment of the pharmacist.

Knowledge of pharmacology facilitates selection of warning labels for drugs dispensed. Pharmacy technicians who
possess a good knowledge of pharmacology understand the importance of recognizing drug interactions,
therapeutic duplication, and excessive dose alerts screened by the computer. Knowing and interpreting lab values
is beyond the scope of a pharmacy technician and is left to the professional judgment of the pharmacist.

5. Which of the following was passed to protect the public from ineffective and harmful drugs and later expanded
to standardize new drugs getting to market? [Multiple Choice]

a. Durham-Humphrey Amendment

b. Controlled Substance Act

c. Pure Food and Drug Act ✔

,d. Combat Methamphetamine Epidemic Act

ANS: C

In 1906, the Pure Food and Drug Act was passed to protect the public from ineffective and harmful drugs. This Act
was expanded in 1938, and standards for allowing new drugs onto the market were set. The Durham-Humphrey
Amendment (1951) established the distinction between legend drugs and drugs that could safely be used by the
public without supervision by a health care provider. The Controlled Substance Act helps regulate controlled
substances by placing them in various schedules based on abuse potential. The Combat Methamphetamine
Epidemic Act regulates, among other things, retail over-the-counter sales of ephedrine, pseudoephedrine, and
phenylpropanolamine products used to manufacture crystal meth.

In 1906, the Pure Food and Drug Act was passed to protect the public from ineffective and harmful drugs. This Act
was expanded in 1938, and standards for allowing new drugs onto the market were set. The Durham-Humphrey
Amendment (1951) established the distinction between legend drugs and drugs that could safely be used by the
public without supervision by a health care provider. The Controlled Substance Act helps regulate controlled
substances by placing them in various schedules based on abuse potential. The Combat Methamphetamine
Epidemic Act regulates, among other things, retail over-the-counter sales of ephedrine, pseudoephedrine, and
phenylpropanolamine products used to manufacture crystal meth.

6. Which of the following is the phase of the drug approval process that initially determines the safety and
efficacy in those with the disease being studied? [Multiple Choice]

a. Phase 1

b. Phase 2 ✔

c. Phase 3

d. Phase 4

ANS: B

In phase 1 clinical trials, the drug is administered to a small number of healthy volunteers who are enrolled in the
clinical study. Phase 2 studies are controlled trials with a limited number of patients with the condition to be
treated. During this phase, data are collected to determine the drug’s efficacy and the drug’s side effects in
patients with the disease. A phase 3 clinical study is when drug safety is evaluated, and the benefit of taking the
drug is compared with the risks associated with taking the drug. Phase 4 trials are studies that are conducted after
the drug is marketed to the public to determine safety and effectiveness when the drug is used in “real-world”
conditions.

In phase 1 clinical trials, the drug is administered to a small number of healthy volunteers who are enrolled in the
clinical study. Phase 2 studies are controlled trials with a limited number of patients with the condition to be
treated. During this phase, data are collected to determine the drug’s efficacy and the drug’s side effects in
patients with the disease. A phase 3 clinical study is when drug safety is evaluated, and the benefit of taking the
drug is compared with the risks associated with taking the drug. Phase 4 trials are studies that are conducted after
the drug is marketed to the public to determine safety and effectiveness when the drug is used in “real-world”

, conditions.

7. Which of the following is the phase of the drug approval process that determines effectiveness of the drug in
healthy volunteers? [Multiple Choice]

a. Phase 1 ✔

b. Phase 2

c. Phase 3

d. Phase 4

ANS: A

In phase 1 clinical trials, the drug is administered to a small number of healthy volunteers who are enrolled in the
clinical study. Phase 2 studies are controlled trials with a limited number of patients with the condition to be
treated. During this phase, data are collected to determine the drug’s efficacy and the drug’s side effects in
patients with the disease. A phase 3 clinical study is when drug safety is evaluated, and the benefit of taking the
drug is compared with the risks associated with taking the drug. Phase 4 trials are studies that are conducted after
the drug is marketed to the public to determine safety and effectiveness when the drug is used in “real-world”
conditions.

In phase 1 clinical trials, the drug is administered to a small number of healthy volunteers who are enrolled in the
clinical study. Phase 2 studies are controlled trials with a limited number of patients with the condition to be
treated. During this phase, data are collected to determine the drug’s efficacy and the drug’s side effects in
patients with the disease. A phase 3 clinical study is when drug safety is evaluated, and the benefit of taking the
drug is compared with the risks associated with taking the drug. Phase 4 trials are studies that are conducted after
the drug is marketed to the public to determine safety and effectiveness when the drug is used in “real-world”
conditions.

8. One of the main purposes of drug therapy is to _____. [Multiple Choice]

a. analyze symptoms

b. maintain side effects produced by drug therapy

c. eradicate disease

d. help cure disease ✔

ANS: D

The aim of drug therapy is to diagnose, treat, cure, or lessen the symptoms of disease. Analyzing symptoms is part
of the process and drug therapy may be changed based on the results, but it’s not the main purpose of drug
therapy. Maintaining side effects implies that drug therapy is to only maintain or control side effects and not
diagnose, treat, cure, or lessen the symptoms of disease. While some drug therapies can help eradicate disease, it
is not the main purpose since most diseases can only be cured and eliminated.

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