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Test Bank for Basic and Clinical Pharmacology, 15th Edition by Bertram Katzung — Complete Chapters with Questions & Answers

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This is the complete Test Bank for Basic and Clinical Pharmacology, 15th Edition, authored by Bertram Katzung. The document provides multiple-choice, multiple-response, and case-based questions with correct answers and detailed rationales covering all sections and chapters of the textbook. Content spans Section I Basic Principles (the nature of drugs and drug development and regulation, drug receptors and pharmacodynamics, pharmacokinetics and pharmacodynamics, drug biotransformation, and pharmacogenomics); Section II Autonomic Drugs (introduction to autonomic pharmacology, cholinoceptor-activating and cholinesterase-inhibiting drugs, cholinoceptor-blocking drugs, adrenoceptor agonists and sympathomimetic drugs, and adrenoceptor antagonist drugs); Section III Cardiovascular-Renal Drugs (antihypertensive agents, vasodilators and the treatment of angina pectoris, drugs used in heart failure, agents used in cardiac arrhythmias, and diuretic agents); Section IV Drugs with Important Actions on Smooth Muscle (histamine, serotonin, and the ergot alkaloids, vasoactive peptides, the eicosanoids, nitric oxide, and drugs used in asthma); Section V Drugs That Act in the Central Nervous System (introduction to the pharmacology of CNS drugs, sedative-hypnotic drugs, the alcohols, antiseizure drugs, general anesthetics, local anesthetics, skeletal muscle relaxants, pharmacologic management of parkinsonism and other movement disorders, antipsychotic agents and lithium, antidepressant agents, opioid agonists and antagonists, and drugs of abuse); Section VI Drugs Used to Treat Diseases of the Blood, Inflammation, and Gout (agents used in cytopenias and hematopoietic growth factors, drugs used in disorders of coagulation, agents used in dyslipidemia, and nonsteroidal anti-inflammatory drugs, disease-modifying antirheumatic drugs, nonopioid analgesics, and drugs used in gout); Section VII Endocrine Drugs (hypothalamic and pituitary hormones, thyroid and antithyroid drugs, adrenocorticosteroids and adrenocortical antagonists, the gonadal hormones and inhibitors, pancreatic hormones and antidiabetic drugs, and agents that affect bone mineral homeostasis); Section VIII Chemotherapeutic Drugs (beta-lactam and other cell wall- and membrane-active antibiotics, tetracyclines, macrolides, clindamycin, chloramphenicol, streptogramins, and oxazolidinones, aminoglycosides and spectinomycin, sulfonamides, trimethoprim, and quinolones, antimycobacterial drugs, antifungal agents, antiviral agents, miscellaneous antimicrobial agents including disinfectants, antiseptics, and sterilants, clinical use of antimicrobial agents, antiprotozoal drugs, clinical pharmacology of the antihelmintic drugs, cancer chemotherapy, and immunopharmacology); Section IX Toxicology (introduction to toxicology, heavy metal intoxication and chelators, and management of the poisoned patient); and Section X Special Topics (special aspects of perinatal and pediatric pharmacology, special aspects of geriatric pharmacology, dermatologic pharmacology, drugs used in the treatment of gastrointestinal diseases, therapeutic and toxic potential of over-the-counter agents, dietary supplements and herbal medications, rational prescribing and prescription writing, and important drug interactions and their mechanisms). Topics tested include pharmacotherapeutics, pharmacoeconomics, pharmacokinetics, pharmacodynamics, pharmacogenomics, bioavailability, drug scheduling and the DEA, FDA drug development phases, teratogenicity and pregnancy categories, orphan drugs, generic substitution, adverse drug effects, drug-drug and drug-food interactions, receptor pharmacology, agonist and antagonist mechanisms, first-pass effect, half-life calculations, critical concentration, therapeutic range, enzyme induction and inhibition, CYP450 interactions, autonomic pharmacology, cholinergic and adrenergic agents, cardiovascular pharmacology, antihypertensives, antianginals, heart failure drugs, antiarrhythmics, diuretics, smooth muscle pharmacology, CNS pharmacology, antiseizure drugs, anesthetics, muscle relaxants, antiparkinson agents, antipsychotics, antidepressants, opioid analgesics, drugs of abuse, hematologic agents, anticoagulants, antihyperlipidemics, NSAIDs, DMARDs, gout drugs, endocrine pharmacology, thyroid drugs, corticosteroids, gonadal hormones, antidiabetic agents, bone mineral agents, antimicrobial

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@PROFDOCDIGITALLIBRARIES




TEST BANK
BASIC AND CLINICAL
PHARMACOLOGY
15th Edition
By: Bertram Katzung

,@PROFDOCDIGITALLIBRARIES




Test Bank for Basic and Clinical Pharmacology 15th Edition by Bertram Katzung
Table of Contents:
Section I: Basic principles
Chapter 1: Introduction: the nature of drugs & drug development & regulation
Chapter 2: Drug receptors & pharmacodynamics
Chapter 3: Pharmacokinetics & pharmacodynamics: rational dosing & the time course of
drug action
Chapter 4: Drug biotransformation
Chapter 5: Pharmacogenomics
Section II: Autonomic drugs
Chapter 6: Introduction to autonomic pharmacology
Chapter 7: Cholinoceptor-activating & cholinesterase-inhibiting drugs
Chapter 8: Cholinoceptor-blocking drugs
Chapter 9: Adrenoceptor agonists & sympathomimetic drugs
Chapter 10: Adrenoceptor antagonist drugs
Section III: Cardiovascular-renal drugs
Chapter 11: Antihypertensive agents
Chapter 12: Vasodilators & the treatment of angina pectoris
Chapter 13: Drugs used in heart failure
Chapter 14: Agents used in cardiac arrhythmias
Chapter 15: Diuretic agents
Section IV: Drugs with important actions on smooth muscle
Chapter 16: Histamine, serotonin, & the ergot alkaloids
Chapter 17: Vasoactive peptides
Chapter 18: The Eicosanoids: prostaglandins, thromboxanes, leukotrienes, & related
compounds
Chapter 19: Nitric oxide
Chapter 20: Drugs used in asthma
Section V: Drugs that act in the central nervous system
Chapter 21: Introduction to the pharmacology of cns drugs
Chapter 22: Sedative-hypnotic drugs
Chapter 23: The Alcohols
Chapter 24: Antiseizure drugs
Chapter 25: General anesthetics
Chapter 26: Local anesthetics
Chapter 27: Skeletal muscle relaxants
Chapter 28: Pharmacologic management of parkinsonism & other movement disorders
Chapter 29: Antipsychotic agents & lithium
Chapter 30: Antidepressant agents
Chapter 31: Opioid agonists & antagonists

,@PROFDOCDIGITALLIBRARIES




Chapter 32: Drugs of abuse
Section VI: Drugs used to treat diseases of the blood, inflammation, & gout
Chapter 33: Agents used in cytopenias; hematopoietic growth factors
Chapter 34: Drugs used in disorders of coagulation
Chapter 35: Agents used in dyslipidemia
Chapter 36: Nonsteroidal anti-inflammatory drugs, disease-modifying antirheumatic
drugs, nonopioid analgesics, & drugs used in gout
Section VII: Endocrine drugs
Chapter 37: Hypothalamic & pituitary hormones
Chapter 38: Thyroid & antithyroid drugs
Chapter 39: Adrenocorticosteroids & adrenocortical antagonists
Chapter 40: The Gonadal hormones & inhibitors
Chapter 41: Pancreatic hormones & antidiabetic drugs
Chapter 42: Agents that affect bone mineral homeostasis
Section VIII: Chemotherapeutic drugs
Chapter 43: Beta-lactam & other cell wall- & membrane-active antibiotics
Chapter 44: Tetracyclines, macrolides, clindamycin, chloramphenicol, streptogramins, &
oxazolidinones
Chapter 45: Aminoglycosides & spectinomycin
Chapter 46: Sulfonamides, trimethoprim, & quinolones
Chapter 47: Antimycobacterial drugs
Chapter 48: Antifungal agents
Chapter 49: Antiviral agents
Chapter 50: Miscellaneous antimicrobial agents; disinfectants, antiseptics, & sterilants
Chapter 51: Clinical use of antimicrobial agents
Chapter 52: Antiprotozoal drugs
Chapter 53: Clinical pharmacology of the antihelminthic drugs
Chapter 54: Cancer chemotherapy
Chapter 55: Immunopharmacology
Section IX: Toxicology
Chapter 56: Introduction to toxicology: occupational & environmental
Chapter 57: Heavy metal intoxication & chelators
Chapter 58: Management of the poisoned patient
Section X: Special topics
Chapter 59: Special aspects of perinatal & pediatric pharmacology
Chapter 60: Special aspects of geriatric pharmacology
Chapter 61: Dermatologic pharmacology
Chapter 62: Drugs used in the treatment of gastrointestinal diseases
Chapter 63: Therapeutic & toxic potential of over-the-counter agents
Chapter 64: Dietary supplements & herbal medications
Chapter 65: Rational prescribing & prescription writing
Chapter 66: Important drug interactions & their mechanisms

, @PROFDOCDIGITALLIBRARIES




Test Bank for Basic and Clinical Pharmacology 15th Edition by Bertram Katzung
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation


1. A nurse working in radiology administers iodine to a patient who is having a
computed tomography (CT) scan. The nurse working on the oncology unit
administers chemotherapy to patients who have cancer. At the Public Health
Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to
a 14-month-old child as a routine immunization. Which branch of
pharmacology best describes the actions of all three nurses?

A) Pharmacoeconomics

B) Pharmacotherapeutics

C) Pharmacodynamics

D) Pharmacokinetics

Ans: B

Feedback:

Pharmacology is the study of the biologic effects of chemicals. Nurses are
involved with clinical pharmacology or pharmacotherapeutics, which is a
branch of pharmacology that deals with the uses of drugs to treat, prevent,
and diagnose disease. The radiology nurse is administering a drug to help
diagnose a disease. The oncology nurse is administering a drug to help treat a
disease. Pharmacoeconomics includes any costs involved in drug therapy.
Pharmacodynamics involves how a drug affects the body and
pharmacokinetics is how the body acts on the body.


2. A physician has ordered intramuscular (IM) injections of morphine, a
narcotic, every 4 hours as needed for pain in a motor vehicle accident victim.
The nurse is aware this drug has a high abuse potential. Under what category
would morphine be classified?

A) Schedule I

B) Schedule II




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