NBME - NEW TESTS ACTUAL TEST
QUESTIONS AND ANSWERS
2026/2027(Quiz bank with all the
correct answers)(usmle step
1)Medical examination
Terms in this set (1325)
Decreased Osteoclast Activity
62 year old woman -
osteoporosis – a
bisphosphonate is prescribed.
The expected beneficial effect of
the drug is due to which of the
following?
Cohot Study of elderly women – Statistically Significant Overall Increase
Risk relative risk ratio for hip fractures
among those who exercise regularly is
1.2 (95% confidence interval of 1.1
to 1.8). Which of the following is
the conclusion about the effect of
exercise on the risk of hip
fracture?
,52 year old man goes to ER with chest Increased nitric oxide
concentration pain radiating to his jaw while
shoveling snow. Pulse is 80/min
and blood pressure is 130/70. The
most immediate treatment
mechanism of action?
24 year old woman – spilled hot a. Vascular Endothelial Growth Factor
grease on her left leg while working at VEGF – stimulates angiogenesiss.
a fast-food restaurant. Exam of leg TYPE III Collagen = Blood Vessels – early wound
shows 7cm pink, soft, granular, repair
edematous wound. The
formation of this tissue was
most likely caused by increased
activity of which?
27 year old man- MVC – skull x-ray a. Adenylyl Cyclase
shows a linear, nondepressed basal Adenylate Cyclase – ATP – CAMP -- PROTEKINASE
A
skull fracture – increased serum osm --
Ca and decreased urin osm. Following
v2
desmopressin urine osm increases.
Desmopressin’s effect is due to the
activation of which of the following?
A 10 month old boy – 4 day history of Mediation of Cell Entry via a fusion protein
fever and cough. He attends day
care center. Chest exam shows
intercostal retractions along
with bilateral, diffuse wheezes
and expiratory rhonchi. The
infectious agent most likely has
which of the following
properties?
,A 17 year old girl in ED – 15 minutes B2- Agonist
after being stung by a bee.
Mild light headedness but no
difficulty swallowing- Bilateral
wheezing - Which is most
appropriate
pharmacotherapy for this
patient?
14 year old boy - 2 day history of sore Infectious Mononucleosis
throat and fever that peaks in late
afternoon. 1 week of fatigue. He
recentaly had sex with one
partner. Physical exam show
cervical lymphadenopathy and
pharyngeal erythema with a
creamy exudate. DX?
57 year old man – radiation therapy for
G1 squamous cell carcinoma of the
lung.
Despite therapy, tumor increases
in size and he dies 6 months
later. The progressive tumor
growth is due to a defect in cell
cycle arrest in which of the
following phases of cell cycle?
28 year old – lived in sub-Saharan
Schistosomiasis Africa – until he came to the US.
Temp
of 100.4 – imaging shows
bilateral hydroureter and
hydronephrosis. Biopsy
shows marked fibrosis and
scattered granulomas. DX?
A couple with a family history of a- 50%
thalassemia. Woman has one
, gene deletion and man has
two gene deletion. If the two
gene is trans – what
percentage of offspring will
have a two gene deletion?
QUESTIONS AND ANSWERS
2026/2027(Quiz bank with all the
correct answers)(usmle step
1)Medical examination
Terms in this set (1325)
Decreased Osteoclast Activity
62 year old woman -
osteoporosis – a
bisphosphonate is prescribed.
The expected beneficial effect of
the drug is due to which of the
following?
Cohot Study of elderly women – Statistically Significant Overall Increase
Risk relative risk ratio for hip fractures
among those who exercise regularly is
1.2 (95% confidence interval of 1.1
to 1.8). Which of the following is
the conclusion about the effect of
exercise on the risk of hip
fracture?
,52 year old man goes to ER with chest Increased nitric oxide
concentration pain radiating to his jaw while
shoveling snow. Pulse is 80/min
and blood pressure is 130/70. The
most immediate treatment
mechanism of action?
24 year old woman – spilled hot a. Vascular Endothelial Growth Factor
grease on her left leg while working at VEGF – stimulates angiogenesiss.
a fast-food restaurant. Exam of leg TYPE III Collagen = Blood Vessels – early wound
shows 7cm pink, soft, granular, repair
edematous wound. The
formation of this tissue was
most likely caused by increased
activity of which?
27 year old man- MVC – skull x-ray a. Adenylyl Cyclase
shows a linear, nondepressed basal Adenylate Cyclase – ATP – CAMP -- PROTEKINASE
A
skull fracture – increased serum osm --
Ca and decreased urin osm. Following
v2
desmopressin urine osm increases.
Desmopressin’s effect is due to the
activation of which of the following?
A 10 month old boy – 4 day history of Mediation of Cell Entry via a fusion protein
fever and cough. He attends day
care center. Chest exam shows
intercostal retractions along
with bilateral, diffuse wheezes
and expiratory rhonchi. The
infectious agent most likely has
which of the following
properties?
,A 17 year old girl in ED – 15 minutes B2- Agonist
after being stung by a bee.
Mild light headedness but no
difficulty swallowing- Bilateral
wheezing - Which is most
appropriate
pharmacotherapy for this
patient?
14 year old boy - 2 day history of sore Infectious Mononucleosis
throat and fever that peaks in late
afternoon. 1 week of fatigue. He
recentaly had sex with one
partner. Physical exam show
cervical lymphadenopathy and
pharyngeal erythema with a
creamy exudate. DX?
57 year old man – radiation therapy for
G1 squamous cell carcinoma of the
lung.
Despite therapy, tumor increases
in size and he dies 6 months
later. The progressive tumor
growth is due to a defect in cell
cycle arrest in which of the
following phases of cell cycle?
28 year old – lived in sub-Saharan
Schistosomiasis Africa – until he came to the US.
Temp
of 100.4 – imaging shows
bilateral hydroureter and
hydronephrosis. Biopsy
shows marked fibrosis and
scattered granulomas. DX?
A couple with a family history of a- 50%
thalassemia. Woman has one
, gene deletion and man has
two gene deletion. If the two
gene is trans – what
percentage of offspring will
have a two gene deletion?
