NBCRNA NATIONAL CERTIFICATION EXAM (NCE)
QUESTIONS AND CORRECT ANSWERS (VERIFIED
ANSWERS) Q&A 2027 |INSTANT DOWNLAOD PDF
1. Which phase of the action potential is primarily associated
with rapid depolarization of a ventricular myocyte?
A. Phase 0
B. Phase 1
C. Phase 2
D. Phase 4
Answer: A. Phase 0
Rationale: Phase 0 represents rapid depolarization caused
primarily by opening of fast sodium channels.
2. Which receptor is primarily responsible for bronchial
smooth-muscle relaxation when stimulated?
A. α1
B. β1
C. β2
D. M2
Answer: C. β2
Rationale: β2-adrenergic stimulation activates Gs pathways,
increasing cAMP and producing bronchodilation.
,3. What is the primary determinant of oxygen delivery (DO₂)?
A. Hemoglobin concentration and arterial oxygen content
B. Venous oxygen saturation alone
C. Respiratory rate alone
D. Serum bicarbonate
Answer: A. Hemoglobin concentration and arterial oxygen
content
Rationale: Oxygen delivery depends mainly on cardiac output
and arterial oxygen content, which is strongly influenced by
hemoglobin concentration and saturation.
4. Which anesthetic agent has the lowest blood-gas partition
coefficient among the commonly used volatile anesthetics?
A. Isoflurane
B. Sevoflurane
C. Desflurane
D. Halothane
Answer: C. Desflurane
Rationale: Desflurane has very low blood solubility,
contributing to rapid changes in alveolar and anesthetic partial
pressures.
5. What is the most important immediate treatment for
severe opioid-induced respiratory depression?
,A. Administer atropine
B. Support ventilation and administer naloxone when
appropriate
C. Administer furosemide
D. Give sodium bicarbonate
Answer: B. Support ventilation and administer naloxone when
appropriate
Rationale: Airway and ventilatory support are priorities;
naloxone reverses opioid-mediated respiratory depression.
6. Which local anesthetic is an amide?
A. Procaine
B. Chloroprocaine
C. Tetracaine
D. Lidocaine
Answer: D. Lidocaine
Rationale: Lidocaine is an amide local anesthetic. Procaine,
chloroprocaine, and tetracaine are esters.
7. Which factor shifts the oxyhemoglobin dissociation curve to
the right?
A. Hypothermia
B. Decreased 2,3-DPG
, C. Increased hydrogen ion concentration
D. Hypocapnia
Answer: C. Increased hydrogen ion concentration
Rationale: Acidosis decreases hemoglobin's affinity for oxygen
and shifts the curve to the right, facilitating oxygen unloading.
8. Which opioid is characterized by an ultra-short duration of
action due largely to rapid metabolism by nonspecific
esterases?
A. Morphine
B. Fentanyl
C. Remifentanil
D. Methadone
Answer: C. Remifentanil
Rationale: Remifentanil is rapidly metabolized by nonspecific
blood and tissue esterases.
9. What is the primary site of cerebrospinal fluid production?
A. Arachnoid villi
B. Choroid plexus
C. Dural sinuses
D. Pituitary gland
QUESTIONS AND CORRECT ANSWERS (VERIFIED
ANSWERS) Q&A 2027 |INSTANT DOWNLAOD PDF
1. Which phase of the action potential is primarily associated
with rapid depolarization of a ventricular myocyte?
A. Phase 0
B. Phase 1
C. Phase 2
D. Phase 4
Answer: A. Phase 0
Rationale: Phase 0 represents rapid depolarization caused
primarily by opening of fast sodium channels.
2. Which receptor is primarily responsible for bronchial
smooth-muscle relaxation when stimulated?
A. α1
B. β1
C. β2
D. M2
Answer: C. β2
Rationale: β2-adrenergic stimulation activates Gs pathways,
increasing cAMP and producing bronchodilation.
,3. What is the primary determinant of oxygen delivery (DO₂)?
A. Hemoglobin concentration and arterial oxygen content
B. Venous oxygen saturation alone
C. Respiratory rate alone
D. Serum bicarbonate
Answer: A. Hemoglobin concentration and arterial oxygen
content
Rationale: Oxygen delivery depends mainly on cardiac output
and arterial oxygen content, which is strongly influenced by
hemoglobin concentration and saturation.
4. Which anesthetic agent has the lowest blood-gas partition
coefficient among the commonly used volatile anesthetics?
A. Isoflurane
B. Sevoflurane
C. Desflurane
D. Halothane
Answer: C. Desflurane
Rationale: Desflurane has very low blood solubility,
contributing to rapid changes in alveolar and anesthetic partial
pressures.
5. What is the most important immediate treatment for
severe opioid-induced respiratory depression?
,A. Administer atropine
B. Support ventilation and administer naloxone when
appropriate
C. Administer furosemide
D. Give sodium bicarbonate
Answer: B. Support ventilation and administer naloxone when
appropriate
Rationale: Airway and ventilatory support are priorities;
naloxone reverses opioid-mediated respiratory depression.
6. Which local anesthetic is an amide?
A. Procaine
B. Chloroprocaine
C. Tetracaine
D. Lidocaine
Answer: D. Lidocaine
Rationale: Lidocaine is an amide local anesthetic. Procaine,
chloroprocaine, and tetracaine are esters.
7. Which factor shifts the oxyhemoglobin dissociation curve to
the right?
A. Hypothermia
B. Decreased 2,3-DPG
, C. Increased hydrogen ion concentration
D. Hypocapnia
Answer: C. Increased hydrogen ion concentration
Rationale: Acidosis decreases hemoglobin's affinity for oxygen
and shifts the curve to the right, facilitating oxygen unloading.
8. Which opioid is characterized by an ultra-short duration of
action due largely to rapid metabolism by nonspecific
esterases?
A. Morphine
B. Fentanyl
C. Remifentanil
D. Methadone
Answer: C. Remifentanil
Rationale: Remifentanil is rapidly metabolized by nonspecific
blood and tissue esterases.
9. What is the primary site of cerebrospinal fluid production?
A. Arachnoid villi
B. Choroid plexus
C. Dural sinuses
D. Pituitary gland
