Turcan SBB Exam Review AABB Packet | Actual Questions and
Answers Latest Updated 2026/2027 (Graded A+)
•
Rh inheritence of Rhnull
i. - ✔✔Lack LW
ii. Lack FY5
•
KEL3 Issues
i. - ✔✔KPa
ii. in cis position may have suppressive effect on other Kell system antigens
•
Adsorption applications in RBC testing
i. - ✔✔Remove autoantibody
ii. Separate multiple antibodies
iii. Confirm antigen or antibody specificity
•
Antilymphocyte Globulin (ALG)
i. - ✔✔Made from horse serum
ii. Interferes with DAT and IAT
iii. Relation to Lu(a-b-)
•
PCR and TMA
i. - ✔✔PCR used for DNA amp
ii. TMA used for RNA amp
•
Autologous donor qualifications
i. - ✔✔DR's order
ii. Hgb >11, HCT 33%
iii. Collected >72 hrs before surgery or Tx
iv. Deferred if risk of bacteremia
•
Plateletpheresis count info
i. - ✔✔>150,000 min
ii. pre procedure plt count not required for infrequent donors
iii. post-procedure plt count may be used to qualify donor for next procedure
,•
Two units RBC apheresis post donation H/H
- ✔✔Donor HCT not <30% or Hgb <10 g/dL after volume replacement following donation
•
Anticoagulants and purpose of
i. - ✔✔Dextrose:
ii. Supports ATP generation
iii. Adenine:
iv. Provides substrate for ATP synthesis
v. Sodium biphosphate:
vi. Controls pH or is buffer
vii. Citrate:
viii. prevents clotting and coagulation
•
Changes in bag upon storage
i. - ✔✔decreases in:
ii. pH
iii. 2,3-DPG
iv. ATP
v. Increases in:
vi. Hgb
vii. K
•
Oxygen dissociation curve information
i. - ✔✔p50 is pO2 level at which Hgb is 50% saturated
ii. A normal p50 is about 25 pO2
iii. increase p50, see right shift, more O2 released
iv. decrease p50, see left shift, less O2 released
•
Reactive test results for TTD action
- ✔✔Reactive results must be retested in duplicate
•
Confirmatory TTD tests
i. - ✔✔Neutralization for HBsAg and HIV-1 Ag WB for Anti-HIV
ii. RIBA for Anti-HCV
iii. Anti-HTLV confirmation
•
No algorithm available for reentry by FDA for these
, - ✔✔HIV and HCV NAT pos tests
•
Components for correction of coagulopathies
i. - ✔✔Plasma
ii. PLTs
iii. Cryo
•
Components for replacing deficient coag factors
i. - ✔✔FFP
ii. Cryo
•
Components for fighting infections
- ✔✔WBCs
•
Use for cryo-poor plasma
- ✔✔treat TTP patients
•
PLTs purpose and contraindication
i. - ✔✔Improve hemostasis
ii. do not give for TTP or ITP unless absolutely necessary
•
Fathers genotype is BO, mom's is OO. Prob to have 3 OO kids?
- ✔✔0.5x0.5x0.5 = .125
•
Calcium's involvement in coag cascade
i. - ✔✔involved at:
ii. 12a and 11 reaction to 11a
iii. 11a and 9 reaction to 9a
iv. 9a's and 8a's reaction on 10 to 10a
v. 10a's and 5a's reaction on prothrombin to thrombin
•
Coag factor enzymes
i. - ✔✔Factor 2a
ii. Factor 7a
iii. Factor 9a
iv. Factor 10a
v. Protein C
Answers Latest Updated 2026/2027 (Graded A+)
•
Rh inheritence of Rhnull
i. - ✔✔Lack LW
ii. Lack FY5
•
KEL3 Issues
i. - ✔✔KPa
ii. in cis position may have suppressive effect on other Kell system antigens
•
Adsorption applications in RBC testing
i. - ✔✔Remove autoantibody
ii. Separate multiple antibodies
iii. Confirm antigen or antibody specificity
•
Antilymphocyte Globulin (ALG)
i. - ✔✔Made from horse serum
ii. Interferes with DAT and IAT
iii. Relation to Lu(a-b-)
•
PCR and TMA
i. - ✔✔PCR used for DNA amp
ii. TMA used for RNA amp
•
Autologous donor qualifications
i. - ✔✔DR's order
ii. Hgb >11, HCT 33%
iii. Collected >72 hrs before surgery or Tx
iv. Deferred if risk of bacteremia
•
Plateletpheresis count info
i. - ✔✔>150,000 min
ii. pre procedure plt count not required for infrequent donors
iii. post-procedure plt count may be used to qualify donor for next procedure
,•
Two units RBC apheresis post donation H/H
- ✔✔Donor HCT not <30% or Hgb <10 g/dL after volume replacement following donation
•
Anticoagulants and purpose of
i. - ✔✔Dextrose:
ii. Supports ATP generation
iii. Adenine:
iv. Provides substrate for ATP synthesis
v. Sodium biphosphate:
vi. Controls pH or is buffer
vii. Citrate:
viii. prevents clotting and coagulation
•
Changes in bag upon storage
i. - ✔✔decreases in:
ii. pH
iii. 2,3-DPG
iv. ATP
v. Increases in:
vi. Hgb
vii. K
•
Oxygen dissociation curve information
i. - ✔✔p50 is pO2 level at which Hgb is 50% saturated
ii. A normal p50 is about 25 pO2
iii. increase p50, see right shift, more O2 released
iv. decrease p50, see left shift, less O2 released
•
Reactive test results for TTD action
- ✔✔Reactive results must be retested in duplicate
•
Confirmatory TTD tests
i. - ✔✔Neutralization for HBsAg and HIV-1 Ag WB for Anti-HIV
ii. RIBA for Anti-HCV
iii. Anti-HTLV confirmation
•
No algorithm available for reentry by FDA for these
, - ✔✔HIV and HCV NAT pos tests
•
Components for correction of coagulopathies
i. - ✔✔Plasma
ii. PLTs
iii. Cryo
•
Components for replacing deficient coag factors
i. - ✔✔FFP
ii. Cryo
•
Components for fighting infections
- ✔✔WBCs
•
Use for cryo-poor plasma
- ✔✔treat TTP patients
•
PLTs purpose and contraindication
i. - ✔✔Improve hemostasis
ii. do not give for TTP or ITP unless absolutely necessary
•
Fathers genotype is BO, mom's is OO. Prob to have 3 OO kids?
- ✔✔0.5x0.5x0.5 = .125
•
Calcium's involvement in coag cascade
i. - ✔✔involved at:
ii. 12a and 11 reaction to 11a
iii. 11a and 9 reaction to 9a
iv. 9a's and 8a's reaction on 10 to 10a
v. 10a's and 5a's reaction on prothrombin to thrombin
•
Coag factor enzymes
i. - ✔✔Factor 2a
ii. Factor 7a
iii. Factor 9a
iv. Factor 10a
v. Protein C
