P R O F E S S I O N A L P R A C T I C E M AT E R I A L S
NR 508 Week 2
Chamberlain 2026/2027 |
Comprehensive Nursing
Questions & Answers |
Updated Course Review
(Rationales)
Verified Answers Exam Ready With Rationales 72 QUESTIONS
DOCUMENT OVERVIEW
This comprehensive review document provides 72 nursing exam questions with pre-
selected correct answers and detailed rationales, covering advanced pharmacology and
health management topics. It is suitable for in-depth study, course review, and certification
preparation, offering a complete learning resource rather than a blank test.
TOPICS
Androgen and Estrogen Therapy Q1–Q13
Contraception and Family Planning Q14–Q33
Erectile Dysfunction and STIs Q34–Q46
Gynecological Conditions and Treatments Q47–Q57
Women's Health Considerations Q58–Q67
Pharmacokinetics and Gender Differences Q68–Q72
Page 1
, E XA M Q U EST I O N S
Q1 QUESTION 1 OF 72
Men who use transdermal testosterone gel (AndroGel) should be advised to avoid:
1. Washing their hands after applying the gel
2. Wearing occlusive clothing while using the gel
3. Exposure to estrogens while using the gel
4. Skin-to-skin contact with pregnant women while using the gel
RESPONSE
4. Skin-to-skin contact with pregnant women while using the gel
RATIONALE
Transdermal testosterone can transfer to others through direct skin contact. This transfer poses a
risk of virilization to pregnant women and their fetuses, necessitating avoidance of such contact.
Providers must counsel patients on safe application and handling practices to prevent secondary
exposure.
Q2 QUESTION 2 OF 72
Education when prescribing androgens to male patients includes advising that:
1. Short-term use places the patient at risk for hepatocellular carcinoma.
2. Cholestatic hepatitis and jaundice may occur with low doses of androgens.
3. Gynecomastia is a rare occurrence with the use of androgens.
4. Low sperm levels only occur with long-term use of androgens.
RESPONSE
2. Cholestatic hepatitis and jaundice may occur with low doses of androgens.
RATIONALE
Androgens can cause hepatotoxicity, manifesting as cholestatic hepatitis and jaundice, even at
therapeutic doses. This adverse effect is linked to the drug's metabolism and potential impact on
liver function. Patients should be educated about this potential side effect during androgen
therapy.
Page 2
, Q3 QUESTION 3 OF 72
Patients who are prescribed exogenous androgens need to be warned that decreased
libido:
1. Is an unusual side effect of androgens and should be reported to the provider
2. Is treated with increased doses of androgens, so the patient should let the provider know
if he is having problems
3. May be a sign of early prostate cancer and he should make an appointment for a prostate
screening exam
4. May occur with androgen therapy
RESPONSE
4. May occur with androgen therapy
RATIONALE
Exogenous androgen administration can lead to paradoxical effects on libido due to complex
feedback mechanisms within the hypothalamic-pituitary-gonadal axis. While androgens are
intended to increase libido, desensitization or other hormonal imbalances can manifest as a
decrease. Therefore, reduced libido is a recognized potential adverse effect of androgen therapy.
Q4 QUESTION 4 OF 72
The U.S. Food and Drug Administration warns that androgens may cause:
1. Peliosis hepatis
2. Orthostatic hypotension
3. Menstrual irregularities
4. Acne
RESPONSE
1. Peliosis hepatis
RATIONALE
Androgens, particularly anabolic steroids, are known to cause significant hepatic toxicity. This can
manifest as peliosis hepatis, a rare condition characterized by blood-filled cysts in the liver. Other
adverse effects, while possible, are not the primary or most severe warning issued by the FDA
regarding androgen use.
Page 3
, Q5 QUESTION 5 OF 72
Monitoring for a patient who is using androgens includes evaluation of:
1. Complete blood count and C-reactive protein levels
2. Lipid levels and liver function tests
3. Serum potassium and magnesium levels
4. Urine protein and potassium levels
RESPONSE
2. Lipid levels and liver function tests
RATIONALE
Androgens can adversely affect lipid profiles by decreasing high-density lipoprotein (HDL)
cholesterol and increasing low-density lipoprotein (LDL) cholesterol. prolonged use of androgens
can lead to hepatotoxicity, necessitating monitoring of liver enzymes. Therefore, regular
assessment of lipid levels and liver function tests is vital for patients undergoing androgen therapy.
Q6 QUESTION 6 OF 72
Male patients require ______________________ before and during androgen therapy.
1. A digital prostate exam
2. A Doppler exam of testicular blood flow
3. Urine analysis for proteinuria
4. Serial orthostatic blood pressures
RESPONSE
1. A digital prostate exam
RATIONALE
Androgen therapy can stimulate prostate growth, potentially exacerbating or unmasking benign
prostatic hyperplasia (BPH) or prostate cancer. A digital rectal examination (DRE) is a key screening
tool to assess prostate size and identify abnormalities before initiating treatment. This allows for
informed clinical decisions regarding patient safety and management.
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