Advanced Pharmacology Exam 1 ACTUAL EXAM [QUESTION 1-
200] AND ANSWERS UPDATED 2026/2027| 100%
VERIFIED|DETAILED RATIONALES –PASS GUARANTEED A+
GRADED |INSTANT DOWNLOAD
A 5-year old child presents to your primary care clinic and has gray teeth. When taking a medication
history, you will ask about previous use of which group of antibiotics?
A. PCN
B. Cephalosporins
C. Sulfonamids
D. Tetracyclines - --CORRECT ANSWER----D
- Tetracyclines cause discoloration of developing teeth in children, which is an adverse effect unique to
this class of antibiotics
- The other drugs listed here don't cause this effect
A blood pressure drug is small, lipid soluble with no charge at all times and is 99% protein bound. The
patient's dose has been titrated and is at the appropriate dose maintain good control of his HTN.
Recently, the patient begins to take daily high doses of an additional OTC drug that is also small, lipid
soluble, carries no charge and is highly protein bound. Which of the following is likely to happen with
the introduction of the second drug?
A. The absorption of the blood pressure drug will increase because it is small, lipid soluble and has no
charge
B. The blood pressure drug will have decreased effectiveness.
C. The patient will need to be monitored as he may become hypotensive.
D. Since both drugs are small, lipid soluble and have no charge, the will compete with eachother at the
same receptor sites on body tissues. - --CORRECT ANSWER----C
If 1 protein-bound drug's dose is titrated for a specific effect, when you add another highly protein
bound drug, both of them will compete for receptor sites on the albumin and more free (think active)
drug will be in the plasma - this puts the person at risk for toxicity/OD from both drugs. These drugs
have different actions and are not competing for the same receptor
,Advanced Pharmacology Exam 1 ACTUAL EXAM [QUESTION 1-
200] AND ANSWERS UPDATED 2026/2027| 100%
VERIFIED|DETAILED RATIONALES –PASS GUARANTEED A+
GRADED |INSTANT DOWNLOAD
A cancer patient is receiving morphine to treat their cancer-related pain. Approximately every 7 days,
the medication is no longer effective in controlling her pain and a larger dose is needed to achieve the
same effect. What is happening?
A. Cumulation effect
B. Drug interactions
C. Drug tolerance
D. Addiction - --CORRECT ANSWER----C
The body may develop a tolerance to some drugs (like narcotics) when used chronically
- When tolerance occurs, the same amount of the drug no longer causes the same reaction so higher
doses are required to achieve a therapeutic effect
A cancer pt is taking Zofran for nausea. How many refills would you give this pt?
A. As many as you want before wanting to see this pt again
B. 12
C. 1
D. None - --CORRECT ANSWER----A. As many as you want before wanting to see this pt again
A medication is a weak base that ionizes at a pH of 4 and lower. The medication is administered orally.
Which of the following statements is accurate?
A. It will be absorbed primarily in the stomach and become ionized once it reaches the small intestine.
B. it will be absorbed primarily in the small intestine and become ionized once it reaches the blood
stream.
C. Whenever it becomes ionized, the drug will attach to an active transport receptor and be carried into
the blood stream.
,Advanced Pharmacology Exam 1 ACTUAL EXAM [QUESTION 1-
200] AND ANSWERS UPDATED 2026/2027| 100%
VERIFIED|DETAILED RATIONALES –PASS GUARANTEED A+
GRADED |INSTANT DOWNLOAD
D. It will be absorbed in the small intestine and be non-ionized in the blood stream and will be able to
enter into a lactating woman's breast milk and also return to the bloodstream from the breast milk. - --
CORRECT ANSWER----D
It is a weak base so, in this case it is a non-ionized in any pH greater than 4 - so it will be absorbed in
small intestines, stay ionized in blood (7.45-7.45) and also be able to enter breast milk; since breast milk
is 7.1, it will not ionize there either; there are not transport receptors for just any drug and they would
not be active transport bc it is not an up gradient situation.
A patient has a localized skin infection, which is most likely caused by a gram positive cocci. Until the
culture & sensitivity results are available, you plan to order a _________ -spectrum _________ drug.
A. broad; systemic
B. broad; topical
C. narrow; systemic
D. narrow; topical - --CORRECT ANSWER----D
- Because this is a localized infection, a topical agent is recommended
- And unless the infection is very serious, a narrow-spectrum antibiotic would be best (choose one with
good gram positive coverage because that is what tends to grow on skin)
A patient has a SNP that creates greater than normal amounts of very efficient/ active forms of CYP 3A4.
This is the enzyme that deactivates drug G. Which of the following is accurate?
A. This patient will need higher doses of drug G in order to have the expected reaction.
B. Because this patient is an ultra-metabolizer, they need to be monitored for drug toxicity when give
standard doses of drug G.
C. For safety reasons, this patient should not be give drug G or any other drugs metabolized by CYP3A4.
, Advanced Pharmacology Exam 1 ACTUAL EXAM [QUESTION 1-
200] AND ANSWERS UPDATED 2026/2027| 100%
VERIFIED|DETAILED RATIONALES –PASS GUARANTEED A+
GRADED |INSTANT DOWNLOAD
D. This SNP will not affect the serum levels of the drug so no changes are needed. - --CORRECT ANSWER-
---A
Because the drug is inactivate by the enzyme and the patient is making more of the enzyme than
expected, the pt would need to take higher doses than usual to get the expected effect.
A patient is taking 2 PO drugs, A and B. Drug A absorbs well in the small intestine, but is poorly absorbed
in the stomach. Drug B absorbs well in the stomach, but is poorly absorbed in the intestines. What is
likely true?
A. Drug A is probably a weak acid and drug B is probably a weak base
B. Drug A is probably a weak base and drug B is probably a weak acid
C. Drug A is a weak base, but becomes an acid when in the stomach
D. Drug B is a weak acid, but becomes a base when in the intestines - --CORRECT ANSWER----B
Always remember that weak acids absorb well in the stomach & weak bases absorb well in the
intestines (because they are not ionized in those body compartments)
A patient presents to the ER with a serum drug level of 50 g/mL. The half-life of this drug is 1 hour. With
this drug, concentrations above 25 g/mL are considered toxic. How long will it take for the blood level to
reach the non-toxic range?
A. 30 minutes
B. 1 hour
C. 2 hours
D. 3 hours - --CORRECT ANSWER----B
- Half-life is the time required for the serum concentration of a drug to reduce by 50%
200] AND ANSWERS UPDATED 2026/2027| 100%
VERIFIED|DETAILED RATIONALES –PASS GUARANTEED A+
GRADED |INSTANT DOWNLOAD
A 5-year old child presents to your primary care clinic and has gray teeth. When taking a medication
history, you will ask about previous use of which group of antibiotics?
A. PCN
B. Cephalosporins
C. Sulfonamids
D. Tetracyclines - --CORRECT ANSWER----D
- Tetracyclines cause discoloration of developing teeth in children, which is an adverse effect unique to
this class of antibiotics
- The other drugs listed here don't cause this effect
A blood pressure drug is small, lipid soluble with no charge at all times and is 99% protein bound. The
patient's dose has been titrated and is at the appropriate dose maintain good control of his HTN.
Recently, the patient begins to take daily high doses of an additional OTC drug that is also small, lipid
soluble, carries no charge and is highly protein bound. Which of the following is likely to happen with
the introduction of the second drug?
A. The absorption of the blood pressure drug will increase because it is small, lipid soluble and has no
charge
B. The blood pressure drug will have decreased effectiveness.
C. The patient will need to be monitored as he may become hypotensive.
D. Since both drugs are small, lipid soluble and have no charge, the will compete with eachother at the
same receptor sites on body tissues. - --CORRECT ANSWER----C
If 1 protein-bound drug's dose is titrated for a specific effect, when you add another highly protein
bound drug, both of them will compete for receptor sites on the albumin and more free (think active)
drug will be in the plasma - this puts the person at risk for toxicity/OD from both drugs. These drugs
have different actions and are not competing for the same receptor
,Advanced Pharmacology Exam 1 ACTUAL EXAM [QUESTION 1-
200] AND ANSWERS UPDATED 2026/2027| 100%
VERIFIED|DETAILED RATIONALES –PASS GUARANTEED A+
GRADED |INSTANT DOWNLOAD
A cancer patient is receiving morphine to treat their cancer-related pain. Approximately every 7 days,
the medication is no longer effective in controlling her pain and a larger dose is needed to achieve the
same effect. What is happening?
A. Cumulation effect
B. Drug interactions
C. Drug tolerance
D. Addiction - --CORRECT ANSWER----C
The body may develop a tolerance to some drugs (like narcotics) when used chronically
- When tolerance occurs, the same amount of the drug no longer causes the same reaction so higher
doses are required to achieve a therapeutic effect
A cancer pt is taking Zofran for nausea. How many refills would you give this pt?
A. As many as you want before wanting to see this pt again
B. 12
C. 1
D. None - --CORRECT ANSWER----A. As many as you want before wanting to see this pt again
A medication is a weak base that ionizes at a pH of 4 and lower. The medication is administered orally.
Which of the following statements is accurate?
A. It will be absorbed primarily in the stomach and become ionized once it reaches the small intestine.
B. it will be absorbed primarily in the small intestine and become ionized once it reaches the blood
stream.
C. Whenever it becomes ionized, the drug will attach to an active transport receptor and be carried into
the blood stream.
,Advanced Pharmacology Exam 1 ACTUAL EXAM [QUESTION 1-
200] AND ANSWERS UPDATED 2026/2027| 100%
VERIFIED|DETAILED RATIONALES –PASS GUARANTEED A+
GRADED |INSTANT DOWNLOAD
D. It will be absorbed in the small intestine and be non-ionized in the blood stream and will be able to
enter into a lactating woman's breast milk and also return to the bloodstream from the breast milk. - --
CORRECT ANSWER----D
It is a weak base so, in this case it is a non-ionized in any pH greater than 4 - so it will be absorbed in
small intestines, stay ionized in blood (7.45-7.45) and also be able to enter breast milk; since breast milk
is 7.1, it will not ionize there either; there are not transport receptors for just any drug and they would
not be active transport bc it is not an up gradient situation.
A patient has a localized skin infection, which is most likely caused by a gram positive cocci. Until the
culture & sensitivity results are available, you plan to order a _________ -spectrum _________ drug.
A. broad; systemic
B. broad; topical
C. narrow; systemic
D. narrow; topical - --CORRECT ANSWER----D
- Because this is a localized infection, a topical agent is recommended
- And unless the infection is very serious, a narrow-spectrum antibiotic would be best (choose one with
good gram positive coverage because that is what tends to grow on skin)
A patient has a SNP that creates greater than normal amounts of very efficient/ active forms of CYP 3A4.
This is the enzyme that deactivates drug G. Which of the following is accurate?
A. This patient will need higher doses of drug G in order to have the expected reaction.
B. Because this patient is an ultra-metabolizer, they need to be monitored for drug toxicity when give
standard doses of drug G.
C. For safety reasons, this patient should not be give drug G or any other drugs metabolized by CYP3A4.
, Advanced Pharmacology Exam 1 ACTUAL EXAM [QUESTION 1-
200] AND ANSWERS UPDATED 2026/2027| 100%
VERIFIED|DETAILED RATIONALES –PASS GUARANTEED A+
GRADED |INSTANT DOWNLOAD
D. This SNP will not affect the serum levels of the drug so no changes are needed. - --CORRECT ANSWER-
---A
Because the drug is inactivate by the enzyme and the patient is making more of the enzyme than
expected, the pt would need to take higher doses than usual to get the expected effect.
A patient is taking 2 PO drugs, A and B. Drug A absorbs well in the small intestine, but is poorly absorbed
in the stomach. Drug B absorbs well in the stomach, but is poorly absorbed in the intestines. What is
likely true?
A. Drug A is probably a weak acid and drug B is probably a weak base
B. Drug A is probably a weak base and drug B is probably a weak acid
C. Drug A is a weak base, but becomes an acid when in the stomach
D. Drug B is a weak acid, but becomes a base when in the intestines - --CORRECT ANSWER----B
Always remember that weak acids absorb well in the stomach & weak bases absorb well in the
intestines (because they are not ionized in those body compartments)
A patient presents to the ER with a serum drug level of 50 g/mL. The half-life of this drug is 1 hour. With
this drug, concentrations above 25 g/mL are considered toxic. How long will it take for the blood level to
reach the non-toxic range?
A. 30 minutes
B. 1 hour
C. 2 hours
D. 3 hours - --CORRECT ANSWER----B
- Half-life is the time required for the serum concentration of a drug to reduce by 50%
