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ATI Pharmacology | Nursing Pharmacology Study Guide, Exam Review & Practice Questions

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Prepare for ATI Pharmacology assessments with a comprehensive nursing pharmacology review resource covering essential medication concepts and safe nursing practice. This study material is designed to help nursing students strengthen their understanding of pharmacologic principles and apply medication knowledge to patient-care situations. Review key areas such as drug classifications, therapeutic effects, adverse reactions, contraindications, precautions, drug interactions, routes of administration, medication safety, dosage considerations, patient education, and nursing interventions. Understanding the relationship between medications, patient assessment, and nursing responsibilities can help reinforce clinical reasoning and improve exam preparation. Use this resource alongside your ATI coursework, nursing textbooks, instructor guidance, and other approved educational materials. It can support organized study, reinforce important pharmacology concepts, and help identify areas that may need additional review before nursing assessments and examinations.

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b. Distended neck veins

A nurse is assessing a client who is receiving
intravenous therapy. The nurse should identify
which of the following findings as a manifestation
of fluid volume excess?
a. Decreased bowel sounds
b. Distended neck veins
c. Bilateral muscle weakness
d. Thread pulse


b. Improved cognition

A nurse is caring for a client who has
hyponatremia and is receiving an infusion of a
prescribed hypertonic solution. Which of the
following findings should indicate to the nurse
that the treatment is effective?
a. Absent Chvostek's sign
b. Improved cognition
c. Decreased vomiting
d. Cardiac arrhythmias absent




d. "Remove the patch prior to going to bed."

A nurse is teaching a client who has a new
prescription for a nitroglycerin transdermal patch.
Which of the following instructions should the
nurse include?
a. "Discontinue the patch if you experience a
headache."
b. "Apply a new patch if you have chest pain."
c. "Cover the patch with dry gauze when taking a
shower."
d. "Remove the patch prior to going to bed."




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d. Potassium 5.2 mEq/L - Hyperkalemia (serum potassium level greater than 5.0 mEq/L)
increases the client risk for fatal cardiac dysrhythmias. Kayexalate is used to decrease the
A nurse is reviewing he laboratory results of a serum potassium level so the PN should monitor the client's serum potassium level
client who has a prescription for sodium
polystyrene sulfonate (Kayexalate) every 6 hr.
which of the following should the nurse report to
the provider?
a. Creatinine 0.72 mg/dL
b. Sodium 138 mEq/L
c. Magnesium 2 mEq/L
d. Potassium 5.2 mEq/L




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a. The client has a negative sputum culture


A nurse is caring for a client who has
tuberculosis and is taking isoniazid and rifampin.
Which of the following outcomes indicates that
the client is adhering to the medication regimen?
a. The client has a negative sputum culture
b. The client tests negative for HIV
c. The client has a positive purified protein
derivative test
d. The client's liver function test results are within
the expected reference range




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d. Administer epinephrine IM

A client is caring for a client who develops an
anaphylactic reaction to IV administration. After
assessing the client's respiratory status and
stopping the medication infusion. Which of the
following actions should the nurse take next?
a. Replace the infusion with 0.9% sodium
chloride
b. Give diphenhydramine IM
c. Elevate the client's legs and feet
d. Administer epinephrine IM




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a. St. John's Wort

A nurse is caring for a client who is taking
sertraline and reports a desire to begin taking
supplements. Which of the following
supplements should the nurse advise the client
to avoid?
a. St. John's Wort
b. Ginger root
c. Black cohosh
d. Coenzyme Q10




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d. Hypotension

A nurse is caring for a client who has heart
failure and a new prescription for lisinopril. For
which of the following adverse effects should the
nurse monitor when administering lisinopril?
a. Bradycardia
b. Hypokalemia
c. Tinnitus
d. Hypotension




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d. Increased blood pressure

A nurse is assessing a client who is receiving
heparin IV continuous IV. The client has an PPT
of 90 seconds. They should monitor the client for
which of the following changes in their vital
signs?
a. Decreased temperature
b. Increased pulse rate
c. Decreased respiratory rate
d. Increased blood pressure




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b. The nurse who identifies the error

A nurse is preparing to administer medication to
a client and discovers a medication error. The
nurse should recognize that which of the
following staff members is responsible for
completing an incident report?
a. The quality improvement committee
b. The nurse who identifies the error
c. The nurse who caused the error
d. The charge nurse




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a. Pruritus - Sign of allergic reaction to morphine

A nurse is planning care for a client who is
receiving morphine via continuous epidural
infusion. The nurse should monitor the client for
which of the following?
a. Pruritus
b. Cough
c. Tachypnea
d. Gastric bleeding




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a. Obtain the client's apical heart rate
A nurse is preparing to administer digoxin orally b. Remove the medication from the dispensing system
to a client. Identify the sequence of steps the c. Open the medication package
nurse should take. (Move the steps into the box d. Compare the client's wristband to the medication administration record
on the right placing them in the order of e. Document administration of the medication
performance. Use all the steps.)




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a. Alcohol use disorder

A nurse is reviewing the medical record of an b. Chronic kidney disease
adult client who has a fever and a prescription
for acetaminophen. Which of the following
findings should the nurse identify as a
contraindication for receiving this medication?
a. Alcohol use disorder
b. Chronic kidney disease
c. Hepatitis B vaccine within the last week
d. Diabetes mellitus




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c. Determine medication adherence by the client


A home health nurse is visiting a client who has
heart failure and a prescription for furosemide.
The nurse identifies that the client has gained
2.5 kg (5 lb.) since the last visit 2 days ago.
Which of the following actions should the nurse
take first?
a. Encourage the client to dangle the legs while
sitting in a chair
b. Teach the client about foods low in sodium
c. Determine medication adherence by the client
d. Notify the provider of the client's weight gain




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a. Urticaria

A nurse is preparing to administer the initial dose
of penicillin G IM to a client. The nurse should
monitor for which of the following as an
indication of an allergic reaction following the
injection?
a. Urticaria
b. Bradycardia
c. Pallor
d. Dyspepsia




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