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NUR 257 Concepts of Aging and Chronic Illness in Nursing Exam Questions & Answers with Rationales – 100 Practice Questions for Geriatric Nursing, Polypharmacy & End-of-Life Care

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The content is divided into five logically structured sections that mirror the scope of a modern geriatric nursing curriculum. Section 1: Theories of Aging and Physiologic Changes covers the free radical and telomere theories, baroreceptor reflex blunting, silent aspiration risk, decreased glomerular filtration rate, skin and gastrointestinal changes, and the critical distinction between normal aging and pathologic conditions such as delirium. Section 2: Geriatric Syndromes and Functional Assessment tests your knowledge of frailty criteria, the Fulmer SPICES tool, the Katz Index and Lawton IADL Scale, fall risk reduction, elder abuse recognition, and dementia versus delirium differentiation. Section 3: Polypharmacy and Pharmacology in Older Adults delivers high-yield questions on the Beers Criteria, STOPP/START criteria, anticholinergic burden, potentially inappropriate medications such as benzodiazepines, diphenhydramine, glyburide, and nitrofurantoin, plus age-related changes in hepatic metabolism and serum albumin that increase adverse drug reaction risk. Section 4: Chronic Disease Management challenges you with realistic clinical scenarios involving COPD oxygen therapy and hypoxic drive, heart failure daily weight monitoring, diabetes foot care and hypoglycemia recognition, chronic kidney disease hyperkalemia and anemia, and the chronic illness trajectory phases from stable to unstable to acute crisis. Section 5: End-of-Life, Palliative Care, and Ethical Issues rounds out your preparation with questions on hospice eligibility, palliative care goals, terminal secretions, living wills, durable power of attorney for healthcare, advance directive conflict resolution, ageism, and the ethical principle of autonomy. Each rationale explains not only why the correct answer is right but also why the distractors are wrong, reinforcing the clinical reasoning skills essential for safe, compassionate practice. This NUR 257 study guide is ideal for self-paced review, classroom supplementation, study groups, and last-minute exam preparation. The question format mirrors the style of nursing school exams and licensure tests, helping you build confidence and reduce test anxiety. Written with clarity and clinical accuracy, it transforms complex gerontological and chronic illness concepts into digestible, memorable, and immediately applicable knowledge. Whether you are mastering the Beers Criteria for the first time or refining your understanding of caregiver burden and respite care, this resource equips you with the knowledge, critical thinking, and test-taking strategies to excel in nursing school and deliver exceptional care to aging populations.

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NUR 257: CONCEPTS OF AGING
AND CHRONIC ILLNESS IN
NURSING, WITH CORRECT
ANSWERS AND RATIONALES.

---



Section 1: Theories of Aging and Physiologic Changes (Questions 1–
20)



1. Which theory of aging proposes that aging results from the
cumulative damage caused by unstable molecules over time?

A) Telomere shortening theory

B) Free radical theory

C) Immunosenescence theory

D) Neuroendocrine theory

Correct Answer: B

Rationale: The free radical theory suggests that oxidative damage
from unstable molecules accumulates in cells over time, leading to
cellular dysfunction and aging. Telomere shortening relates to DNA
replication limits, immunosenescence to immune decline, and
neuroendocrine to hormonal changes .

,2. An 82-year-old patient experiences dizziness upon standing.
Which age-related physiological change is the primary cause of this
presentation?

A) Increased elasticity of the arterial walls

B) Blunting of the baroreceptor reflex

C) Hypertrophy of the left ventricular wall

D) Overactive parasympathetic nervous system

Correct Answer: B

Rationale: The blunting of the baroreceptor reflex impairs the body's
ability to rapidly vasoconstrict and increase heart rate upon
standing. Left ventricular hypertrophy affects diastolic filling, not
positional blood pressure regulation .



3. A 78-year-old patient coughs weakly during meals and clears their
throat repeatedly. Which age-related change most directly
contributes to the risk of silent aspiration?

A) Increased forced expiratory volume

B) Decreased alveolar surface area

C) Reduced sensitivity of the laryngeal cough reflex

D) Calcification of the costal cartilages

Correct Answer: C

Rationale: Diminished sensitivity of the laryngeal cough reflex allows
food or fluid to enter the airway without provoking a strong expulsive
cough, leading to silent aspiration .

,4. Which physiological change of aging necessitates a dose
reduction for renally excreted medications?

A) Increased renal blood flow

B) Decreased glomerular filtration rate

C) Hyperplasia of the nephrons

D) Increased bladder capacity

Correct Answer: B

Rationale: A progressive decline in GFR reduces the kidneys' ability
to clear medications, increasing the risk of drug toxicity. Bladder
capacity actually decreases with age .



5. Which gastrointestinal change in aging increases the risk of
constipation?

A) Increased peristalsis

B) Increased gastric acid

C) Decreased intestinal motility

D) Increased intestinal villi

Correct Answer: C

Rationale: Decreased intestinal motility leads to constipation in older
adults. Other GI changes include decreased gastric acid and
decreased absorption .



6. Which skin change is common in older adults and increases the
risk for pressure ulcers?

A) Increased elasticity

, B) Thicker epidermis

C) Decreased subcutaneous fat

D) Increased moisture

Correct Answer: C

Rationale: Loss of subcutaneous fat reduces cushioning and
increases pressure injury risk. Other skin changes include
decreased elasticity and thinning of the epidermis .



7. Which assessment finding is a normal age-related change in the
older adult?

A) Urinary incontinence

B) Presbyopia

C) Depression

D) Acute confusion

Correct Answer: B

Rationale: Presbyopia (loss of near vision) is a normal age-related
change. Incontinence, depression, and acute confusion are not
normal aging changes and require further assessment .



8. What is the hallmark symptom of delirium?

A) Insidious onset

B) Progressive cognitive decline

C) Acute onset with fluctuating course

D) Gradual memory loss

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September 26, 2026
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