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UAskMe DERMATOLOGIE Klinisch eindexamen (2021GENGE3) - Samenvatting

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Volledige uitwerking van de UAskMe lijst voor het vak DERMATOLOGIE voor het Klinisch Eindexamen. Uitgewerkt adhv de cursus en lesnotities dermatologie, aangevuld met afbeeldingen, overzichtelijke schema's en aangeduid wat de belangrijkste keypoints zijn. Voldoende om te slagen voor zowel het mondeling als het MCQ klinisch eindexamen aan de Universiteit van Antwerpen. (Deel 1/19 van de uitgewerkte UAskMe lijst: zie account voor de andere vakken of de voordeelbundel)

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1.
U ASK ME
DERMATOLOGIE




KLINISCH EINDEXAMEN
2025-2026

,INHOUDSTAFEL
1. Psoriasis ............................................................................................................................................................... 2
2. Pityriasis rosea van Gilbert .................................................................................................................................. 5
3. Eczeem ................................................................................................................................................................ 6
4. Bacteriële, virale en mycologische infecties ...................................................................................................... 11
5. Urticaria, prurigo en pruritus ............................................................................................................................ 27
6. Medicamenteuze erupties, purpura, erythema exsudativum multifome ......................................................... 31
7. Vaatpathologie - Ulcera ..................................................................................................................................... 37
8. Dermatologische oncologie ............................................................................................................................... 40
9. Acné ................................................................................................................................................................... 46
10. Haar- en nagelpathologie ................................................................................................................................ 49
11. Vasculitis, auto-immune en interne aandoeningen ........................................................................................ 53
12. Pigmentstoornissen ......................................................................................................................................... 67
13. Bulleuze aandoeningen ................................................................................................................................... 70
14. Belangrijke aanvullingen ................................................................................................................................. 72




1

,1. PSORIASIS
DEFINITIE

- Chronisch
- Niet infectieus
- Inflammatoir
- NIET besmettelijk

ETHIOPATHOGENESE

ð Genetische inflammatoire epidermale celproliferatie (continue renovatie bovenste huidlaag)

UITLOKKENDE FACTOREN

- Infectie
o Streptococcus pyogenes voor psoriasis guttata (= druppelvorm)
- Medicatie (!)
o Betablokkers
o Antimalariamedicatie (Plaquenil)
o Lithium
- Stress (fysiek en mentaal)

KLINIEK

- Plaque psoriasis
o = scherp afgelijnde, rode plaques met dikke witte schilfering
ó eczeem: niet goed afgelijnd
- Symmetrisch (!)
o Knieën en ellebogen (strekzijde) (ó eczeem in plooien!)
o Lage rug
o Schedelhuid
ð Symmetrisch = oorzaak van binnenuit (bv. medicatie) ó assymetrisch = oorzaak van buitenaf

ANDERE KLINISCHE VORMEN

- Guttata vorm (afb LB)
o = druppelvorm
- Inversa
o In lichaamsplooien
o 3 plaatsen: bilspleet , liezen, navel
§ DD: candida in liesplooi
- Palmoplantair
o Beperkt tot handen en voeten (afb RB)
- Pustuleus (LO en RO)
- Psoriasis erythrodermie
o Rood van kop tot teen (afb)
§ Kan ook door eczeem




2

, - Nagelaantasting
o Onycholyse (afb 1)
§ = loslating van nagelplaat van nagelbed à witte kleur
§ Kan ook door candida, te smalle schoenen
o Pitting = vingerhoedsnagel (afb 2)
§ Enkel bij psoriasis te zien !!
o Olievlekfenomeen (afb 3)
§ Bruin/geel verkleuring van de nagel
o Subunguale hyperkeratose (afb 4)




BEHANDELING

FASE 1: LOKAAL

- Keratolytica
o Vermindert schilfering
- Topische corticoïden
o Anti-inflammatoir
o Zalf > crème
- Vitamine D analogen
o Anti-schilfering
o Calcipotriol (enkel nog in combinatieproducten)
§ Betamethason
+ calpotriol = dovobet®
o Tacalcitol




ð Mogen in gezicht
o Hydrocortisone acetaat
o Clobetazone butyraat
o Triamcinolone acetonide
o Mometasone fuoraat
o Hydrocortisone butyraat




3

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