PCC 1 Review Questions with Verified Correct
Answers
Excipients
inactive ingredients
dosage form
form in which drugs are manufactured
Enternal route
GI tract before Site of action
parenternal route
Avoids GI tract intradermal, subcutaneous, intramuscular, intravenous
first pass metabolism
Loss of portion of drug before reaching SOA
types of administration
Topical, transdermal, pulmonary, oral, injections
Bioavailability
the rate at and the extent to which a drug is absorbed and used at SOA
ADME
absorption, distribution, metabolism, excretion
Plasma Concentration
Amount of drug present in blood plasma.
, Onset of action
The amount of time from the administration of a medication to the onset of effects.
termination of action
point at which a drug effect is no longer seen
minimum toxic concentration (MTC)
The minimum serum drug concentration necessary to begin producing a toxic effect on the
body.
Minimum effective concentration (MEC)
The smallest amount of drug necessary in the blood or target tissue to result in a measurable
intended action.
USAN
United States adopted name
INN
International Nonproprietary Name
therapeutic window
a drugs blood concentration range between its MEC and MTC
Diffusion
Passive transport of drug molecules from higher conc. to lower conc.
Dissolution
Solid drug substance enters liquid solution
Answers
Excipients
inactive ingredients
dosage form
form in which drugs are manufactured
Enternal route
GI tract before Site of action
parenternal route
Avoids GI tract intradermal, subcutaneous, intramuscular, intravenous
first pass metabolism
Loss of portion of drug before reaching SOA
types of administration
Topical, transdermal, pulmonary, oral, injections
Bioavailability
the rate at and the extent to which a drug is absorbed and used at SOA
ADME
absorption, distribution, metabolism, excretion
Plasma Concentration
Amount of drug present in blood plasma.
, Onset of action
The amount of time from the administration of a medication to the onset of effects.
termination of action
point at which a drug effect is no longer seen
minimum toxic concentration (MTC)
The minimum serum drug concentration necessary to begin producing a toxic effect on the
body.
Minimum effective concentration (MEC)
The smallest amount of drug necessary in the blood or target tissue to result in a measurable
intended action.
USAN
United States adopted name
INN
International Nonproprietary Name
therapeutic window
a drugs blood concentration range between its MEC and MTC
Diffusion
Passive transport of drug molecules from higher conc. to lower conc.
Dissolution
Solid drug substance enters liquid solution
