1|Page
Pharmacology Hesi Practice
2|Comprehensive Q&A For Certification
Success 2026
The healthcare provider prescribes pyridostigmine bromide (Mestinon) tablets for
a client with myasthenia gravis (MG). What instruction should the nurse provide
this client?
Increase activity in the afternoon when the medication is most effective.
Take the medication 30 to 45 minutes before eating.
Use a PRN dose for increasing muscular weakness or fasciculations.
Give the client a dietary guide that describes low-protein foods. - correct-answer-
Take the medication 30 to 45 minutes before eating.
What action should the nurse implement to provide analgesic titration for a client
in pain ?
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Teach the client to increase the time range between doses of pain medication.
Monitor the effects of continuous intravenous infusion of narcotic analgesics.
Plan with the client how to use a specific total dose of analgesic over a 24-hour
period.
Determine the optimal analgesic dosage required that causes the least side
effects. - correct-answer-Determine the optimal analgesic dosage required that
causes the least side effects.
Which common side effect should the nurse alert a female client about when
medroxyprogesterone (Depo-Provera) is prescribed?
Leg or calf pain.
Headaches or visual changes.
Vaginal bleeding after discontinuing the medication.
Jaundice during the first 3 weeks of administration. - correct-answer-Vaginal
bleeding after discontinuing the medication.
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Miotic drug therapy for the treatment of glaucoma is based chiefly upon which
physiologic action?
Enhancing aqueous humor outflow.
Inhibiting aqueous humor production.
Maintaining intraocular pressure.
Preventing extraocular infection. - correct-answer-Enhancing aqueous humor
outflow.
A client receives a new prescription for nitroglycerin (Nitrostat) tablets. Which
instruction should the nurse include in this client's teaching?
Take the medication at least an hour before every meal.
Monitor your pulse for 60 seconds before administration.
Place under the tongue as needed every 5 minutes up to 3 times.
Resume normal activities after chest pain relief is obtained. - correct-answer-
Place under the tongue as needed every 5 minutes up to 3 times.
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The nurse administers the initial dose of a fentanyl (Duragesic) transdermal patch
to a client with chronic pain. When monitoring the client an hour later, which
assessment is most important for the nurse to obtain?
Level of consciousness.
Moistness of mucosa.
Bowel sound activity.
Numeric pain scale. - correct-answer-Numeric pain scale.
A client is beginning therapy with montelukast (Singulair) PO 10 mg once a day in
the evening. The client asks the nurse, "When should I begin to feel better?" How
should the nurse respond?
Immediately.
Within 24 hours.
In about 12 hours.
Pharmacology Hesi Practice
2|Comprehensive Q&A For Certification
Success 2026
The healthcare provider prescribes pyridostigmine bromide (Mestinon) tablets for
a client with myasthenia gravis (MG). What instruction should the nurse provide
this client?
Increase activity in the afternoon when the medication is most effective.
Take the medication 30 to 45 minutes before eating.
Use a PRN dose for increasing muscular weakness or fasciculations.
Give the client a dietary guide that describes low-protein foods. - correct-answer-
Take the medication 30 to 45 minutes before eating.
What action should the nurse implement to provide analgesic titration for a client
in pain ?
,2|Page
Teach the client to increase the time range between doses of pain medication.
Monitor the effects of continuous intravenous infusion of narcotic analgesics.
Plan with the client how to use a specific total dose of analgesic over a 24-hour
period.
Determine the optimal analgesic dosage required that causes the least side
effects. - correct-answer-Determine the optimal analgesic dosage required that
causes the least side effects.
Which common side effect should the nurse alert a female client about when
medroxyprogesterone (Depo-Provera) is prescribed?
Leg or calf pain.
Headaches or visual changes.
Vaginal bleeding after discontinuing the medication.
Jaundice during the first 3 weeks of administration. - correct-answer-Vaginal
bleeding after discontinuing the medication.
,3|Page
Miotic drug therapy for the treatment of glaucoma is based chiefly upon which
physiologic action?
Enhancing aqueous humor outflow.
Inhibiting aqueous humor production.
Maintaining intraocular pressure.
Preventing extraocular infection. - correct-answer-Enhancing aqueous humor
outflow.
A client receives a new prescription for nitroglycerin (Nitrostat) tablets. Which
instruction should the nurse include in this client's teaching?
Take the medication at least an hour before every meal.
Monitor your pulse for 60 seconds before administration.
Place under the tongue as needed every 5 minutes up to 3 times.
Resume normal activities after chest pain relief is obtained. - correct-answer-
Place under the tongue as needed every 5 minutes up to 3 times.
, 4|Page
The nurse administers the initial dose of a fentanyl (Duragesic) transdermal patch
to a client with chronic pain. When monitoring the client an hour later, which
assessment is most important for the nurse to obtain?
Level of consciousness.
Moistness of mucosa.
Bowel sound activity.
Numeric pain scale. - correct-answer-Numeric pain scale.
A client is beginning therapy with montelukast (Singulair) PO 10 mg once a day in
the evening. The client asks the nurse, "When should I begin to feel better?" How
should the nurse respond?
Immediately.
Within 24 hours.
In about 12 hours.
