NR 327 Medications List
,./ ,./ ,./
Generic,./Name:,./Betamethasone,./
Trade,./Name:,./Celestone
long-acting,./corticosteroids,./
Pregnancy,./Category,./C
Betamethasone,./are,./used,./to,./accelerate,./maturation,./of,./fetal,./lungs,./if,./preterm,./deliv
ery,./is,./likely.,./
Risk,./category,./L2.,./Prednisone,./and,./prednisolone,./compatible,./with,./breastfeeding.,./
Delay,./nursing,./4,./hr,./after,./dose,./to,./reduce,./transfer,./to,./infant.,./Remove,./from,./nipple
s,./before,./nursing,./if,./applied,./topically.,./-,./correct,./answer,./✔ ✔ ✓Indications
-
Administering,./the,./steroid,./as,./late,./as,./37,./weeks,./of,./gestation,./may,./be,./chosen,./if,./fet
al,./lung,./maturity,./studies,./demonstrate,./immature,./lungs,./later,./than,./34,./weeks.,./
✓ACTION:
,all,./agents,./suppress,./inflammation,./and,./the,./normal,./immune,./response.,./All,./agents,./
have,./numerous,./intense,./metabolic,./effects,./
✓DOSAGE/ROUTE:
IM,,./(ADULT):,./0.5-
9,./mg,./as,./betamethasone,./sodium,./phosphate/acetate,./suspension.,./Prevention,./of,./res
piratory,./distress,./syndrome,./in,./newborn—12,./mg,./daily,./for,./2-
3,./days,./before,./delivery,./(unlabeled).
IM,,./(Children):,./Adrenocortical,./insufficiency—
17.5,./mcg/kg/day,./(500,./mcg/m2/day),./in,./3,./divided,./doses,./every,./3rd,./day,./or,./5.8-
8.75,./mcg/kg,./(166-250,./mcg/m2)/day,./as,./a,./single,./dose.,./
✓CONTRAINIDICATION:,./
Active,./untreated,./infections,./(may,./be,./used,./in,./patients,./being,./treated,./for,./some,./for
ms,./of,./meningitis);,./Lactation:,./Avoid,./chronic,./use;,./Known,./alcohol,,./bisulfite,,./or,./t
artrazine,./hypersensitivity,./or,./intolerance,./(some,./products,./contain,./these,./and,./shoul
d,./be,./avoided,./in,./susceptible,./patients);,./Administration,./of,./live,./virus,./vaccines.
Use,./Cautiously,./in:,./Chronic,./treatment,./(will,./lead,./to,./adrenal,./suppression;,./use,./low
est,./possible,./dose,./for,./shortest,./period,./of,./time);,./Hypothyroidism;,./Immunosuppres
sion.,./Cirrhosis;,./Pedi:,./Children,./(chronic,./use,./will,./result,./in,./↓,./growth;,./use,./lowest,./
possible,./dose,./for,./shortest,./period,./of,./time);,./Stress,./(surgery,,./infections);,./suppleme
ntal,./doses,./may,./be,./needed;,./Potential,./infections,./may,./mask,./signs,./(fever,,./inflamm
ation);,./Traumatic,./brain,./injury,./(high,./doses,./may,./be,./associated,./with,./↑,./mortality);,.
/OB:,./Safety,./not,./established;,./Pedi:,./Neonates,./(avoid,./use,./of,./benzyl,./alcohol,./contai
ning,./injectable,./preparations;,./use,./preservative-free,./formulations).
,✓SIDE,./EFFECTS:
Adverse,./reactions/side,./effects,./are,./much,./more,./common,./with,./high-dose/long-
term,./therapy.
CNS:,./depression,,./euphoria,,./headache,,./↑,./intracranial,./pressure,./(children,./only),,./pe
rsonality,./changes,,./psychoses,,./restlessnes
Generic,./Name:,./Dinoprostone,./
Trade,./Name:,./Cervidil
vaginal,./insert
Other,./brands:,./Prepidil,./Endocervical,./Gel,,./Prostin,./E,./Vaginal,./Suppository,./
Therapeutic:,./cervical,./ripening,./agent,./-,./correct,./answer,./✔ ✔ ✓Indications
Endocervical,./Gel,,./Vaginal,./Insert:,./Used,./to,./"ripen",./the,./cervix,./in,./pregnancy,./at,./or,
./near,./term,./when,./induction,./of,./labor,./is,./indicated.,./Vaginal,./Suppository:,./Induction,
./of,./midtrimester,./abortion,,./Management,./of,./missed,./abortion,./up,./to,./28,./wk,,./Manag
ement,./of,./nonmetastatic,./gestational,./trophoblastic,./disease,./(benign,./hydatidiform,./
mole).
✓ACTION:
Produces,./contractions,./similar,./to,./those,./occurring,./during,./labor,./at,./term,./by,./stimul
ating,./the,./myometrium,./(oxytocic,./effect).,./Initiates,./softening,,./effacement,,./and,./dila
tion,./of,./the,./cervix,./("ripening").,./Also,./stimulates,./GI,./smooth,./muscle.,./Therapeutic,./
Effects:,./Initiation,./of,./labor.,./Expulsion,./of,./fetus.,./
, ✓DOSAGE/ROUTE:
Cervical,./Ripening
Vag,,./(Adults,,./Cervical):,./Endocervical,./gel—
0.5,./mg;,./if,./response,./is,./unfavorable,,./may,./repeat,./in,./6,./hr,./(not,./to,./exceed,./1.5,./mg/2
4,./hr).,./Vaginal,./insert—one,./10-mg,./insert.
Abortifacient
Vag,./(Adults):,./One,./20-mg,./suppository,,./repeat,./q,./3-
5,./hr,./(not,./to,./exceed,./240,./mg,./total,./or,./longer,./than,./48,./hr).
✓CONTRAINIDICATION:,./
Hypersensitivity,./to,./prostaglandins,./or,./additives,./in,./the,./gel,./or,./suppository;,./The,./g
el/insert,./should,./be,./avoided,./in,./situations,./in,./which,./prolonged,./uterine,./contraction
s,./should,./be,./avoided,,./including:,./Previous,./cesarean,./section,./or,./uterine,./surgery;,./C
ephalopelvic,./disproportion;,./Traumatic,./delivery,./or,./difficult,./labor;,./Multiparity,./(≥
6,./term,./pregnancies);,./Hyperactive,./or,./hypertonic,./uterus;,./Fetal,./distress,./(if,./deliver
y,./is,./not,./imminent);,./Unexplained,./vaginal,./bleeding;,./Placenta,./previa;,./Vasa,./previa
;,./Active,./herpes,./genitalis;,./Obstetric,./emergency,./requiring,./surgical,./intervention;,./S
ituations,./in,./which,./vaginal,./delivery,./is,./contraindicated;,./Presence,./of,./acute,./pelvic,./
inflammatory,./disease,./or,./ruptured,./membranes;,./Concurrent,./oxytocic,./therapy,./(wai
t,./for,./30,./min,./after,./removing,./insert,./before,./using,./oxytocin).
Use,./Cautiously,./in:,./Uterine,./scarring;,./Asthma;,./Hypotension;,./Cardiac,./disease;,./Ad
renal,./disorders;,./Anemia;,./Jau
,./ ,./ ,./
Generic,./Name:,./Betamethasone,./
Trade,./Name:,./Celestone
long-acting,./corticosteroids,./
Pregnancy,./Category,./C
Betamethasone,./are,./used,./to,./accelerate,./maturation,./of,./fetal,./lungs,./if,./preterm,./deliv
ery,./is,./likely.,./
Risk,./category,./L2.,./Prednisone,./and,./prednisolone,./compatible,./with,./breastfeeding.,./
Delay,./nursing,./4,./hr,./after,./dose,./to,./reduce,./transfer,./to,./infant.,./Remove,./from,./nipple
s,./before,./nursing,./if,./applied,./topically.,./-,./correct,./answer,./✔ ✔ ✓Indications
-
Administering,./the,./steroid,./as,./late,./as,./37,./weeks,./of,./gestation,./may,./be,./chosen,./if,./fet
al,./lung,./maturity,./studies,./demonstrate,./immature,./lungs,./later,./than,./34,./weeks.,./
✓ACTION:
,all,./agents,./suppress,./inflammation,./and,./the,./normal,./immune,./response.,./All,./agents,./
have,./numerous,./intense,./metabolic,./effects,./
✓DOSAGE/ROUTE:
IM,,./(ADULT):,./0.5-
9,./mg,./as,./betamethasone,./sodium,./phosphate/acetate,./suspension.,./Prevention,./of,./res
piratory,./distress,./syndrome,./in,./newborn—12,./mg,./daily,./for,./2-
3,./days,./before,./delivery,./(unlabeled).
IM,,./(Children):,./Adrenocortical,./insufficiency—
17.5,./mcg/kg/day,./(500,./mcg/m2/day),./in,./3,./divided,./doses,./every,./3rd,./day,./or,./5.8-
8.75,./mcg/kg,./(166-250,./mcg/m2)/day,./as,./a,./single,./dose.,./
✓CONTRAINIDICATION:,./
Active,./untreated,./infections,./(may,./be,./used,./in,./patients,./being,./treated,./for,./some,./for
ms,./of,./meningitis);,./Lactation:,./Avoid,./chronic,./use;,./Known,./alcohol,,./bisulfite,,./or,./t
artrazine,./hypersensitivity,./or,./intolerance,./(some,./products,./contain,./these,./and,./shoul
d,./be,./avoided,./in,./susceptible,./patients);,./Administration,./of,./live,./virus,./vaccines.
Use,./Cautiously,./in:,./Chronic,./treatment,./(will,./lead,./to,./adrenal,./suppression;,./use,./low
est,./possible,./dose,./for,./shortest,./period,./of,./time);,./Hypothyroidism;,./Immunosuppres
sion.,./Cirrhosis;,./Pedi:,./Children,./(chronic,./use,./will,./result,./in,./↓,./growth;,./use,./lowest,./
possible,./dose,./for,./shortest,./period,./of,./time);,./Stress,./(surgery,,./infections);,./suppleme
ntal,./doses,./may,./be,./needed;,./Potential,./infections,./may,./mask,./signs,./(fever,,./inflamm
ation);,./Traumatic,./brain,./injury,./(high,./doses,./may,./be,./associated,./with,./↑,./mortality);,.
/OB:,./Safety,./not,./established;,./Pedi:,./Neonates,./(avoid,./use,./of,./benzyl,./alcohol,./contai
ning,./injectable,./preparations;,./use,./preservative-free,./formulations).
,✓SIDE,./EFFECTS:
Adverse,./reactions/side,./effects,./are,./much,./more,./common,./with,./high-dose/long-
term,./therapy.
CNS:,./depression,,./euphoria,,./headache,,./↑,./intracranial,./pressure,./(children,./only),,./pe
rsonality,./changes,,./psychoses,,./restlessnes
Generic,./Name:,./Dinoprostone,./
Trade,./Name:,./Cervidil
vaginal,./insert
Other,./brands:,./Prepidil,./Endocervical,./Gel,,./Prostin,./E,./Vaginal,./Suppository,./
Therapeutic:,./cervical,./ripening,./agent,./-,./correct,./answer,./✔ ✔ ✓Indications
Endocervical,./Gel,,./Vaginal,./Insert:,./Used,./to,./"ripen",./the,./cervix,./in,./pregnancy,./at,./or,
./near,./term,./when,./induction,./of,./labor,./is,./indicated.,./Vaginal,./Suppository:,./Induction,
./of,./midtrimester,./abortion,,./Management,./of,./missed,./abortion,./up,./to,./28,./wk,,./Manag
ement,./of,./nonmetastatic,./gestational,./trophoblastic,./disease,./(benign,./hydatidiform,./
mole).
✓ACTION:
Produces,./contractions,./similar,./to,./those,./occurring,./during,./labor,./at,./term,./by,./stimul
ating,./the,./myometrium,./(oxytocic,./effect).,./Initiates,./softening,,./effacement,,./and,./dila
tion,./of,./the,./cervix,./("ripening").,./Also,./stimulates,./GI,./smooth,./muscle.,./Therapeutic,./
Effects:,./Initiation,./of,./labor.,./Expulsion,./of,./fetus.,./
, ✓DOSAGE/ROUTE:
Cervical,./Ripening
Vag,,./(Adults,,./Cervical):,./Endocervical,./gel—
0.5,./mg;,./if,./response,./is,./unfavorable,,./may,./repeat,./in,./6,./hr,./(not,./to,./exceed,./1.5,./mg/2
4,./hr).,./Vaginal,./insert—one,./10-mg,./insert.
Abortifacient
Vag,./(Adults):,./One,./20-mg,./suppository,,./repeat,./q,./3-
5,./hr,./(not,./to,./exceed,./240,./mg,./total,./or,./longer,./than,./48,./hr).
✓CONTRAINIDICATION:,./
Hypersensitivity,./to,./prostaglandins,./or,./additives,./in,./the,./gel,./or,./suppository;,./The,./g
el/insert,./should,./be,./avoided,./in,./situations,./in,./which,./prolonged,./uterine,./contraction
s,./should,./be,./avoided,,./including:,./Previous,./cesarean,./section,./or,./uterine,./surgery;,./C
ephalopelvic,./disproportion;,./Traumatic,./delivery,./or,./difficult,./labor;,./Multiparity,./(≥
6,./term,./pregnancies);,./Hyperactive,./or,./hypertonic,./uterus;,./Fetal,./distress,./(if,./deliver
y,./is,./not,./imminent);,./Unexplained,./vaginal,./bleeding;,./Placenta,./previa;,./Vasa,./previa
;,./Active,./herpes,./genitalis;,./Obstetric,./emergency,./requiring,./surgical,./intervention;,./S
ituations,./in,./which,./vaginal,./delivery,./is,./contraindicated;,./Presence,./of,./acute,./pelvic,./
inflammatory,./disease,./or,./ruptured,./membranes;,./Concurrent,./oxytocic,./therapy,./(wai
t,./for,./30,./min,./after,./removing,./insert,./before,./using,./oxytocin).
Use,./Cautiously,./in:,./Uterine,./scarring;,./Asthma;,./Hypotension;,./Cardiac,./disease;,./Ad
renal,./disorders;,./Anemia;,./Jau
