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Exam 1_ L1 (1)!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~&&&&&&&&########
Exam 1: L1
-drug
-indication
-time
-dose
-patient
-route
-documentation - ✔Drug Administration: What are the 7 rights?
-intradermal
-subcutaneous
-intramuscular
-intravenous - ✔Routes: Parenteral
-liver: primary; Hepatic microsomal enzyme system (CYP450)
-kidney
GI tract - ✔Pharmacokinetics: Metabolism, what are the sites for metabolism? what is the primary?
-oral: enteric coated, sustained release (SR, XL, LA)
-sublingual/buccal
-ODT
-NG/G-tube - ✔Routes: Enteral
-preclinical investigation
-clinical investigation
-review of the New Drug Application (NDA)
-post marketing surveillance****: most frequent for nurses to participate in process r/t monitoring
therapeutic effect and adverse reactions - ✔Drug Regulation: What are the stages of approval?
-primary factor determining onset of action
-rate of dissolution: how rapidly drug disintegrates to become bioavailable which can be influenced by
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Exam 1_ L1 (1)Exam 1_ L1 (1)!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~&&&&&
,~~~&&&&&&&&############################@@@@@@@@@@@@@@@@22/2026//2027
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Exam 1_ L1 (1)!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~&&&&&&&&########
formulation, food, route, dose, pt condition - ✔Pharmacokinetics: Absorption
-responsible for drug safety and effectiveness
-changes to drug review process has availability of new drugs sooner - ✔Drug Regulation: Food and
Drug Administrations (FDA)
-with MAR
-when pouring
-before administering - ✔Controlled Drugs and Substances: What are the 3 checks
a drug following administration - ✔What is a medication?
a drug with restricted use - ✔Controlled Drugs and Substances: What is a controlled substance?
a written order for a drug from one who is legally authorized by license - ✔What is a prescription?
ability of the drug to produce the desired affect - ✔What is bioavailability?
Absorption: where the body assimilates or takes the drug in distribution
Distribution: where drug becomes disseminated to different areas and reaches target areas
Metabolism: where body transforms the drug into a substance that it can eliminate
Excretion: where body removes the drug - ✔What are the 4 phases of pharmakinetics?
additional reaction (beyond expected therapeutic response) that can be beneficial or unwanted -
✔Unexpected outcomes: Side effect
agents naturally produced in animals, by microorganisms, or by the body itself (ex. hormones, blood
products, vaccines) - ✔What is biologic?
alert signifying extreme adverse drug reactions were identified during or after the review process -
✔Drug Regulation: What is a Black Box Warning?
amount of time for the concentration of a drug to decrease by half; helps determine how frequently a
drug needs to be dosed - ✔What is a half-life of a drug?
application of drugs to prevent or treat disease - ✔What is pharmacotherapy?
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Exam 1_ L1 (1)Exam 1_ L1 (1)!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~&&&&&
!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~&&&&&&&&############################@@@
Exam 1_ L1 (1)!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~&&&&&&&&########
Exam 1: L1
-drug
-indication
-time
-dose
-patient
-route
-documentation - ✔Drug Administration: What are the 7 rights?
-intradermal
-subcutaneous
-intramuscular
-intravenous - ✔Routes: Parenteral
-liver: primary; Hepatic microsomal enzyme system (CYP450)
-kidney
GI tract - ✔Pharmacokinetics: Metabolism, what are the sites for metabolism? what is the primary?
-oral: enteric coated, sustained release (SR, XL, LA)
-sublingual/buccal
-ODT
-NG/G-tube - ✔Routes: Enteral
-preclinical investigation
-clinical investigation
-review of the New Drug Application (NDA)
-post marketing surveillance****: most frequent for nurses to participate in process r/t monitoring
therapeutic effect and adverse reactions - ✔Drug Regulation: What are the stages of approval?
-primary factor determining onset of action
-rate of dissolution: how rapidly drug disintegrates to become bioavailable which can be influenced by
~~~&&&&&&&&############################@@@@@@@@@@@@@@@@22/2026//2027
!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~&&&&&&&&############################@@@@@@@@
Exam 1_ L1 (1)Exam 1_ L1 (1)!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~&&&&&
,~~~&&&&&&&&############################@@@@@@@@@@@@@@@@22/2026//2027
!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~&&&&&&&&############################@@@
Exam 1_ L1 (1)!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~&&&&&&&&########
formulation, food, route, dose, pt condition - ✔Pharmacokinetics: Absorption
-responsible for drug safety and effectiveness
-changes to drug review process has availability of new drugs sooner - ✔Drug Regulation: Food and
Drug Administrations (FDA)
-with MAR
-when pouring
-before administering - ✔Controlled Drugs and Substances: What are the 3 checks
a drug following administration - ✔What is a medication?
a drug with restricted use - ✔Controlled Drugs and Substances: What is a controlled substance?
a written order for a drug from one who is legally authorized by license - ✔What is a prescription?
ability of the drug to produce the desired affect - ✔What is bioavailability?
Absorption: where the body assimilates or takes the drug in distribution
Distribution: where drug becomes disseminated to different areas and reaches target areas
Metabolism: where body transforms the drug into a substance that it can eliminate
Excretion: where body removes the drug - ✔What are the 4 phases of pharmakinetics?
additional reaction (beyond expected therapeutic response) that can be beneficial or unwanted -
✔Unexpected outcomes: Side effect
agents naturally produced in animals, by microorganisms, or by the body itself (ex. hormones, blood
products, vaccines) - ✔What is biologic?
alert signifying extreme adverse drug reactions were identified during or after the review process -
✔Drug Regulation: What is a Black Box Warning?
amount of time for the concentration of a drug to decrease by half; helps determine how frequently a
drug needs to be dosed - ✔What is a half-life of a drug?
application of drugs to prevent or treat disease - ✔What is pharmacotherapy?
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Exam 1_ L1 (1)Exam 1_ L1 (1)!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~&&&&&
