WM.a-j - What’s in a medicine? | WM1-5
WM.Q Exam questions from past papers
● NaOH reacts with both the phenol and
carboxyl (functional) groups to give
NaOC6H4COONa
● Na2CO3 only reacts with the carboxyl
(functional) group to give HOC6H4COONa
● The carboxyl (functional) group is more
acidic than the phenol (functional) group
Use acid-base chemistry to explain these observations and
include the structural formula for the organic product of each
reaction.
● 4 hydroxybenzoic acid reacts with both sodium hydroxide
and sodium carbonate solutions
1. The reaction with sodium hydroxide gives a compound
with the molecular formula C7H4O3Na2
2. The reaction with sodium carbonate gives a compound
with the molecular formula C7H5O3Na
● Sodium sulfate (Anhydrous)
● Conc H2SO4
● Silica gel
Name a drying agent that could be used? ● Sodium carbonate (Anhydrous)
, ● [13CC5H5OH]+ / [13CC5H6O]+
Give the formula of the ion that causes the peak at m/z = 95? (2)
1. Fizzing
2. Solid dissolves
3. A colourless solution
4. Change in temperature
Allow fruity smell (as an ester is formed)
Describe 2 things that the student would observe? 4-HBA is
solid.
● Seal/melt end of melting point/capillary tube
● Tap/tip/pack a small amount of solid to
bottom of tube
● Put tube in mp apparatus allow temperature
to rise slowly until solid melts OR record
when it first starts to melt and when it
finishes
Describe the practical procedure used to measure the melting
point of an organic solid?
, ● If more than 1 spot shows up on TLC
● Phenyl benzoate impure
● However cannot assess overall purity /
cannot tell how pure or impure it is
● It's not quantitative / it's qualitative
Comment on the validity of this statement? Phenyl benzoate is
the ester that is formed in esterification from phenol and benzoic
acid
WM.a-b - Organic functional groups | WM1 | WM2 |
Functional group and suffix of aldehydes
and name this compound (Think primary
carboxyl group)
● Functional group:
● Suffix: -al
● Propanal
WM.Q Exam questions from past papers
● NaOH reacts with both the phenol and
carboxyl (functional) groups to give
NaOC6H4COONa
● Na2CO3 only reacts with the carboxyl
(functional) group to give HOC6H4COONa
● The carboxyl (functional) group is more
acidic than the phenol (functional) group
Use acid-base chemistry to explain these observations and
include the structural formula for the organic product of each
reaction.
● 4 hydroxybenzoic acid reacts with both sodium hydroxide
and sodium carbonate solutions
1. The reaction with sodium hydroxide gives a compound
with the molecular formula C7H4O3Na2
2. The reaction with sodium carbonate gives a compound
with the molecular formula C7H5O3Na
● Sodium sulfate (Anhydrous)
● Conc H2SO4
● Silica gel
Name a drying agent that could be used? ● Sodium carbonate (Anhydrous)
, ● [13CC5H5OH]+ / [13CC5H6O]+
Give the formula of the ion that causes the peak at m/z = 95? (2)
1. Fizzing
2. Solid dissolves
3. A colourless solution
4. Change in temperature
Allow fruity smell (as an ester is formed)
Describe 2 things that the student would observe? 4-HBA is
solid.
● Seal/melt end of melting point/capillary tube
● Tap/tip/pack a small amount of solid to
bottom of tube
● Put tube in mp apparatus allow temperature
to rise slowly until solid melts OR record
when it first starts to melt and when it
finishes
Describe the practical procedure used to measure the melting
point of an organic solid?
, ● If more than 1 spot shows up on TLC
● Phenyl benzoate impure
● However cannot assess overall purity /
cannot tell how pure or impure it is
● It's not quantitative / it's qualitative
Comment on the validity of this statement? Phenyl benzoate is
the ester that is formed in esterification from phenol and benzoic
acid
WM.a-b - Organic functional groups | WM1 | WM2 |
Functional group and suffix of aldehydes
and name this compound (Think primary
carboxyl group)
● Functional group:
● Suffix: -al
● Propanal
