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WGU D116 PRE-ASSESSMENT 2026/2027 | COMPLETE EXAM PREP | HIGH-YIELD PRACTICE QUESTIONS & VERIFIED ANSWERS | COMPREHENSIVE STUDY GUIDE | LATEST UPDATED VERSION

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Prepare for the WGU D116 Pre-Assessment with high-yield practice questions, verified answers, and focused review covering key advanced pharmacology concepts. Updated for 2026/2027 and designed for effective exam preparation and review.

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WGU D116 PRE-ASSESSMENT 2026/2027 | COMPLETE EXAM PREP
| HIGH-YIELD PRACTICE QUESTIONS & VERIFIED ANSWERS |
COMPREHENSIVE STUDY GUIDE | LATEST UPDATED VERSION
1. You have been treating a 68-year-old man suffering from chronic CHF with
furosemide (Lasix), a β-blocker, and an ACE inhibitor. Despite this therapy, he
continues with refractory edema. In his baseline state, he is comfortable at
rest, but experiences some symptoms of heart failure with ordinary activity.
Which of the following would be the best diuretic to add?

Metolazone (Zaroxolyn)

Hydrochlorothiazide and triamterene combined (Dyazide, Maxzide)

Hydrochlorothiazide

Spironolactone (Aldactone)

Triamterene

2. An advanced practice registered nurse (APRN) is seeing a 52-year-old
patient whose chief complaint is migraine headaches. The patient reports
seeing a herbalist who provided a supplement for migraine headaches. The
patient is currently taking the following alternative therapies: butterbur, black
cohosh, coenzyme Q10, and echinacea. The patient is not sure which
supplement focuses on decreasing headaches. The APRN is including
instructions in the patient education about alternative therapies and wishes to
highlight the one that decreases migraine headaches. Which alternative
therapy should the APRN highlight?

Echinacea

Black cohosh

Butterbur

Coenzyme Q10

,3. An advanced practice registered nurse (APRN) is following up with a 48-
year-old female who has type 2 diabetes. The woman's self-monitored fasting
glucose results range from 79-126, and her HbA1c level is 7.5. When does this
result need to be rechecked by the APRN?

Repeat in six months

Repeat in one month

Repeat in one year

Repeat in three months

4. A client is receiving an intravenous lidocaine infusion after being converted
from ventricular tachycardia. The client begins to display signs of confusion,
anxiety, agitation, and restlessness. What should the nurse do first?

Turn off the lidocaine infusion.

Notify the client's health care provider.

Increase the rate of lidocaine infusion.

Administer oxygen at 4 L per nasal cannula.

5. The patient has been prescribed enalapril for hypertension. The patient asks
the nurse how the medication lowers blood pressure. The nurse understands
that ACE inhibitors lower blood pressure through.

Vasodilation and sodium/water excretion.

Decreased heart rate.

Sodium/water excretion.

Vasodilation.

,6. Describe the role of proton pump inhibitors in the management of patients
on long-term NSAIDs.

Proton pump inhibitors reduce stomach acid production, helping to
prevent gastric ulcers in patients taking NSAIDs.

Proton pump inhibitors are only effective for short-term use.

Proton pump inhibitors are used to treat infections caused by NSAIDs.

Proton pump inhibitors increase the effectiveness of NSAIDs.

7. Which of the following agents should be AVOIDED if possible in the
management of nausea and vomiting during pregnancy?

Dimenhydrinate

Cyclizine

Dicyclomine

Metoclopramide

8. What is a common adverse effect of prolonged use of phenylephrine nasal
spray?

Dizziness

Rebound congestion

Nausea

Dry mouth

9. If a 35-year-old female patient continues to forget her oral contraceptive
pills despite counseling, what alternative contraceptive method could you
recommend that aligns with her lifestyle?

Intrauterine device (IUD)

, Contraceptive injections

Contraceptive implants

Daily oral contraceptive pills

10. If a 72-year-old male patient with diabetes is prescribed a new medication
that interacts with his existing treatments, what should the APRN do to
ensure adherence?

Change the patient's diet to avoid interactions.

Review the medication regimen for potential interactions and
educate the patient.

Ignore the interactions and proceed with the prescription.

Prescribe a higher dose of the new medication.

11. In a clinical scenario where a pregnant patient experiences severe nausea
and vomiting, which alternative medication could an APRN consider that is
generally deemed safer?

Aspirin

Thalidomide

Ondansetron

Ibuprofen

12. The rationale for using dobutamine (Dobutrex) at an infusion rate of 10-12
mcg/kg/min for cardiogenic shock is to

decrease oxygen consumption

improve myocardial contraction

decrease myocardial ischemia

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