2026 | Advanced Pathophysiology Exam Prep & Study Guide
Axpatientxisxdiagnosedxwithxaxkidneyxstonexthatxisxcomposedxofxmagnesium,xammonium,xandxphosphat
e.xWhatxtypexofxurinaryxcalculusxisxthis?
A)xCalcium
B)xStruvite
C)xUricxacid
D)xIndinavirx-xcorrectxanswerx ✅B)xStruvite
Axpatientxhasxuncontrolledxorxprematurexcontractionsxofxthexdetrusorxmuscle.xWhichxconditionxisxassoc
iatedxwithxthisxmedicalxproblem?
A)xSpinalxcordxinjury
B)xImmunexsystemxdysfunction
C)xCongestivexheartxfailure
D)xRenalxcarcinomax-xcorrectxanswerx ✅A)xSpinalxcordxinjury
Whichxstatementxregardingxrenalxcellxcarcinomaxisxcorrect?
A)xItxisxassociatedxwithxp53.
B)xSymptomsxincludexpainlessxhematuria.
C)xEarlyxstagesxproducexaxlargexabdominalxmass.
D)xGranularxcellxtumorsxhavexbetterxprognosis.x-
xcorrectxanswerx ✅B)xSymptomsxincludexpainlessxhematuria.
Axpatientxwhoxreportsxabdominalxandxbackxpainxhasxbeenxdiagnosedxwithxbacteriaxinxthexurine.xWhatxis
xthexappropriatextermxforxinvolvementxofxthexupperxurinaryxtractxthatxisxlikelyxtoxcausexsuchxsymptoms
?
A)xCystitis
B)xPyelonephritis
C)xUrinaryxtractxinfection
D)xAsymptomaticxbacteriuriax-xcorrectxanswerx ✅B)xPyelonephritis
,Withxwhichxbacteriaxisxacutexglomerulonephritisxassociated?
A)xEscherichiaxcoli
B)xStaphylococcus
C)xGroupxAxStreptococcus
D)xKlebsiellax-xcorrectxanswerx ✅C)xGroupxAxStreptococcus
Axdiabeticxchildxwithx4.0xgxofxproteinxinxherxurinexeachxdayxisxexperiencingxedemaxandxvitaminxDxdeficie
ncy.xWhichxisxthexmostxlikelyxdiagnosis?
A)xNephriticxsyndrome
B)xNephroticxsyndrome
C)xAcutexrenalxfailure
D)xRapidlyxprogressivexglomerulonephritisx-xcorrectxanswerx ✅Nephroticxsyndrome
Ax2-month-
oldxmalexpatientxpresentsxwithxthexurethralxopeningxonxthexdorsalxsurfacexofxthexpenis.xWhichxtermxisxt
hexcorrectxnamexforxthisxanomaly?
A)xHypospadias
B)xEpispadias
C)xExstrophy
D)xUreteropelvicxjunctionx-xcorrectxanswerx ✅Epispadias
Axpatientxpresentsxwithxwide-setxeyes,x"parrotxbeak"xnose,xlow-
setxears,xandxrecedingxchin.xWhatxisxthexrenalxmanifestationxassociatedxwithxthisxpresentation?
A)xPotterxsyndrome
B)xPolycysticxkidneyxdisease
C)xInfundibularxstenosis
D)xMegacalycosisx-xcorrectxanswerx ✅Potterxsyndrome
,Ax6-year-
oldxhasxjustxrecoveredxfromxstreptococcalxpharyngitis.xWhichxstatementxregardingxthisxchild'sxacutexpos
tstreptococcalxglomerulonephritisxisxtrue?
A)xAntibody-antigenxcomplexesxofxIgM,xIgG,xandxIgAxarexdeposited.
B)xThexexactxmechanismxofximmunexcomplexesxisxunknown.
C)xTherexisxdecreasedxvascularxpermeability.
D)xNoxsignsxofxinflammationxarexpresent.x-
xcorrectxanswerx ✅Thexexactxmechanismxofximmunexcomplexesxisxunknown.
Axpatientxpresentsxwithxskinxlesionsxasxwellxasxhematuria,xproteinuria,xandxabdominalxpain.xWhichxisxth
exmostxlikelyxcausexofxthesexsymptoms?
A)xHenoch-Schonleinxpurpura
B)xHemolyticxuremicxsyndrome
C)xPrimaryxnephroticxsyndrome
D)xMinimalxchangexnephropathyx-xcorrectxanswerx ✅Henoch-Schonleinxpurpura
Whatxisxthexcausexofxminimalxchangexnephropathy?
A)xFusionxofxthexglomerularxfootxprocesses
B)xVerotoxinxofxE.xcoli
C)xIgAxdeposition
D)xInflammationxofxthexglomerulix-xcorrectxanswerx ✅Fusionxofxthexglomerularxfootxprocesses
Axchildxwhosexkidneysxarexenlargedxpresentsxwithxchills,xfever,xandxabdominalxpain.xThexmostxlikelyxdia
gnosisxis:
A)xacutexpyelonephritis.
B)xvesicoureteralxreflux.
C)xurinaryxtractxinfection.
D)xenuresis.x-xcorrectxanswerx ✅acutexpyelonephritis
Whatxarexthexmajorxcausesxofxbladderxoutletxobstruction?
, A)xUrethralxvalvesxandxpolyps
B)xKidneyxstonesxandxWilms'xtumor
C)xKidneyxstonesxandxwarts
D)xUrethralxvalvesxandxwartsx-xcorrectxanswerx ✅Urethralxvalvesxandxpolyps
Whichxconditionsxarexcomplicationsxofxaxhorseshoexkidney?x(selectxallxthatxapply)
A)xHydronephrosis
B)xHypospadias
C)xInfection
D)xStonexformationx
E)xEnuresisx-xcorrectxanswerx ✅Hydronephrosis
Infection
Stonexformation
Thexdevelopmentxofxwhichxcharacteristicxisxthexfirstxsignxofxpubertyxinxfemales?
A)xMenarche
B)xPubicxhair
C)xThelarche
D)xDysmenorrheax-xcorrectxanswerx ✅Thelarche
Whichxtermxdescribesxpainfulxmenstruationxassociatedxwithxthexreleasexofxprostaglandinsxinxovulatoryx
cycles?
A)xPrimaryxdysmenorrhea
B)xPrimaryxamenorrhea
C)xSecondaryxdysmenorrhea
D)xSecondaryxamenorrheax-xcorrectxanswerx ✅Primaryxdysmenorrhea
Whichxconditionxmustxbexruledxoutxwhenxidentifyingxthexcausexofxsecondaryxamenorrhea?
A)xAbnormalxthyroidxfunction