NURS 601 PHARM INTRO EXAM 1 2026 LATEST
UPDATE QUESTIONS AND CORRECT VERIFIED
ANSWERS ALREADY GRADED A+
malathion - ANS-organophosphate (pesticide) that is an irreversible cholinesterase inhibitor
two examples of irreversible cholinesterase inhibitors - ANS-*sarin*-nerve gas that is an
irreversible cholinesterase inhibitor
*malathion*-organophosphate (pesticide) that is an irreversible cholinesterase inhibitor
anticholinergic drugs - ANS-antimuscarinic, neuromuscular jxn blockers, and ganglionic
blocking drugs
antimuscarinic drugs - ANS-atropine and scopolamine, act as competitive receptor blockers a
postganglionic postsynaptic muscarinic receptor sites
which muscarinic receptors are most important to us (dentists)? - ANS-M3 receptors are most
important to us (involved in salivary flow)
neuromuscular jxn blockers - ANS-curare, succinycholine, these act at nicotinic receptors at the
neuromuscular jxn of skeletal muscle causing paralysis
ganglionic blocking drugs - ANS-hexamethonium, bind to nicotinic receptors at autonomic
ganglionic level (not great because there is lack of specificity)
antimuscarinic drug effects - ANS-decreased salivation, lacrimation, urination, defecation, GI
mobility, and bronchial constrictions, increased HR due to block of vagal reflex, pupillary
, dilation (mydriasis), drowsiness, hallucinations (dry as a bone, hot as hell, red as a beet, blind
as a bat, mad as a hatter)
contraindications to antimuscarinic drugs - ANS-glaucoma, prostate hypertrophy (dont want to
retain even more urine), intestinal obstruction, pts with cardiovascular and pulmonary
disease bc atropine increases pulse rate without increasing cardiac output
list of antimuscarinic drugs - ANS-scopolamine, benzotropine, aropine, homatropine,
pirenzipine, propantheline, oxybutynin, opratropium bromide (atrovent), tolterodine tartrate
(detrol)
antimuscarinic DDIs - ANS-antihistamines, MAO inhibitors, and Tricyclic antidepressants (all
work by anticholinergic activity), these will potentiate the action
nondepolarizing neruomuscular (nicotinic) jxn blockers - ANS-competitive receptor blockers,
*D-tubocurarine (curare)*, can be reversed because we can increase the agonist to
overwhelm the drug
depolarizing neuromuscular (nicotinic) jxn blockers - ANS-agonists that cause a block because
they provide prolonged stimulation leading to depolarization, *succinylcholine*, can not be
reversed
botox - ANS-indirect acting drug, preventing release of Ach, reduces wrinkles and gives some
thereapy by inducing paralysis, can be used dentally for something like bruxism or esthetically
for a gummy smile
what is the neruotransmitter for the cholinergic system?
the adrenergic system? - ANS-acetylcholine
norepinephrine
UPDATE QUESTIONS AND CORRECT VERIFIED
ANSWERS ALREADY GRADED A+
malathion - ANS-organophosphate (pesticide) that is an irreversible cholinesterase inhibitor
two examples of irreversible cholinesterase inhibitors - ANS-*sarin*-nerve gas that is an
irreversible cholinesterase inhibitor
*malathion*-organophosphate (pesticide) that is an irreversible cholinesterase inhibitor
anticholinergic drugs - ANS-antimuscarinic, neuromuscular jxn blockers, and ganglionic
blocking drugs
antimuscarinic drugs - ANS-atropine and scopolamine, act as competitive receptor blockers a
postganglionic postsynaptic muscarinic receptor sites
which muscarinic receptors are most important to us (dentists)? - ANS-M3 receptors are most
important to us (involved in salivary flow)
neuromuscular jxn blockers - ANS-curare, succinycholine, these act at nicotinic receptors at the
neuromuscular jxn of skeletal muscle causing paralysis
ganglionic blocking drugs - ANS-hexamethonium, bind to nicotinic receptors at autonomic
ganglionic level (not great because there is lack of specificity)
antimuscarinic drug effects - ANS-decreased salivation, lacrimation, urination, defecation, GI
mobility, and bronchial constrictions, increased HR due to block of vagal reflex, pupillary
, dilation (mydriasis), drowsiness, hallucinations (dry as a bone, hot as hell, red as a beet, blind
as a bat, mad as a hatter)
contraindications to antimuscarinic drugs - ANS-glaucoma, prostate hypertrophy (dont want to
retain even more urine), intestinal obstruction, pts with cardiovascular and pulmonary
disease bc atropine increases pulse rate without increasing cardiac output
list of antimuscarinic drugs - ANS-scopolamine, benzotropine, aropine, homatropine,
pirenzipine, propantheline, oxybutynin, opratropium bromide (atrovent), tolterodine tartrate
(detrol)
antimuscarinic DDIs - ANS-antihistamines, MAO inhibitors, and Tricyclic antidepressants (all
work by anticholinergic activity), these will potentiate the action
nondepolarizing neruomuscular (nicotinic) jxn blockers - ANS-competitive receptor blockers,
*D-tubocurarine (curare)*, can be reversed because we can increase the agonist to
overwhelm the drug
depolarizing neuromuscular (nicotinic) jxn blockers - ANS-agonists that cause a block because
they provide prolonged stimulation leading to depolarization, *succinylcholine*, can not be
reversed
botox - ANS-indirect acting drug, preventing release of Ach, reduces wrinkles and gives some
thereapy by inducing paralysis, can be used dentally for something like bruxism or esthetically
for a gummy smile
what is the neruotransmitter for the cholinergic system?
the adrenergic system? - ANS-acetylcholine
norepinephrine
