NR566/NR 566 MIDTERM EXAM REVIEW Questions with
Verified Answers (Correct Update)
Question 1: Which non-amphetamines are FDA approved for weight loss that have lower abuse
risk?
Answer: Phentermine and Diethylpropion
Question 2: How does Phentermine and Diethylpropion promote weight loss?
Answer: -Promote weight loss by decreasing appetite
-They are central nervous system (CNS) stimulants that suppress appetite by increasing the availability
of norepinephrine at receptors in the brain
Question 3: What is the maximum recommended duration of use for nonamphetamines?
Answer: 3 months or less
Question 4: What drug schedule are Phentermine and Diethylpropion under?
Answer: Schedule IV
Question 5: What labs should be monitored with Phentermine and Diethylpropion? What
condition should we screen for?
Answer: -baseline CMP (watch electrolytes and creatinine)
-screen for depression
Question 6: Phentermine adverse effects
Answer: -increase HR and BP
-dry mouth and constipation
Question 7: What is role of topiramate in weight loss?
Answer: Increases satiety
Question 8: What are some Phentermine/topiramate contraindications for use?
Answer: not approved in children and contraindicated with severe hepatic impairment
Question 9: How should we educate patient to take Phentermine/topiramate to avoid insomnia?
Answer: given before 1600
Page 1
, Question 10: What are some high-risk patient conditions that we should use
Phentermine/topiramate with caution?
Answer: hx drug abuse, glaucoma, pregnant, HTN, hyperthyroidism
Question 11: Phentermine/topiramate adverse effects
Answer: insomnia, nervousness, anxiety, depression, blurred vision
Question 12: Which of the following would be a contraindication to prescribing
phentermine/topiramate? Select all that apply.
Answer: A) Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E ANSWER: A,C,D
Question 13: Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of
fat by 30%.
Answer: GI tract
Question 14: Take multivitamin ___hours before/after to supplement fatsoluble vitamins that
may not be absorbed well when taking Orlistat.
Answer: 2
Question 15: Orlistat is OTC as 60 mg TID with meals. Not approved in children <____.
Answer: 12
Question 16: Orlistat results in the least amount of weight loss of all. How much?
Answer: 2-3% body weight (7 lbs in year)
Question 17: Orlistat adverse effects
Answer: Fecal incontinence, oily rectal leakage, flatus, abdominal cramps. liver damage (light-colored
stools, dark urine, fatigue, jaundice, anorexia)
Question 18: When is Orlistat contraindicated?
Answer: In those with malabsorption syndrome or cholestasis
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Verified Answers (Correct Update)
Question 1: Which non-amphetamines are FDA approved for weight loss that have lower abuse
risk?
Answer: Phentermine and Diethylpropion
Question 2: How does Phentermine and Diethylpropion promote weight loss?
Answer: -Promote weight loss by decreasing appetite
-They are central nervous system (CNS) stimulants that suppress appetite by increasing the availability
of norepinephrine at receptors in the brain
Question 3: What is the maximum recommended duration of use for nonamphetamines?
Answer: 3 months or less
Question 4: What drug schedule are Phentermine and Diethylpropion under?
Answer: Schedule IV
Question 5: What labs should be monitored with Phentermine and Diethylpropion? What
condition should we screen for?
Answer: -baseline CMP (watch electrolytes and creatinine)
-screen for depression
Question 6: Phentermine adverse effects
Answer: -increase HR and BP
-dry mouth and constipation
Question 7: What is role of topiramate in weight loss?
Answer: Increases satiety
Question 8: What are some Phentermine/topiramate contraindications for use?
Answer: not approved in children and contraindicated with severe hepatic impairment
Question 9: How should we educate patient to take Phentermine/topiramate to avoid insomnia?
Answer: given before 1600
Page 1
, Question 10: What are some high-risk patient conditions that we should use
Phentermine/topiramate with caution?
Answer: hx drug abuse, glaucoma, pregnant, HTN, hyperthyroidism
Question 11: Phentermine/topiramate adverse effects
Answer: insomnia, nervousness, anxiety, depression, blurred vision
Question 12: Which of the following would be a contraindication to prescribing
phentermine/topiramate? Select all that apply.
Answer: A) Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E ANSWER: A,C,D
Question 13: Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of
fat by 30%.
Answer: GI tract
Question 14: Take multivitamin ___hours before/after to supplement fatsoluble vitamins that
may not be absorbed well when taking Orlistat.
Answer: 2
Question 15: Orlistat is OTC as 60 mg TID with meals. Not approved in children <____.
Answer: 12
Question 16: Orlistat results in the least amount of weight loss of all. How much?
Answer: 2-3% body weight (7 lbs in year)
Question 17: Orlistat adverse effects
Answer: Fecal incontinence, oily rectal leakage, flatus, abdominal cramps. liver damage (light-colored
stools, dark urine, fatigue, jaundice, anorexia)
Question 18: When is Orlistat contraindicated?
Answer: In those with malabsorption syndrome or cholestasis
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