NR 566 Adv Pharm for Family Chamberlain Questions with
Verified Answers (Correct Update)
Question 1: Antibiotic Classes and examples of infectious disease drugs
Answer: ß-Lactams : penicillins
-Penicillin G, V
-Nafcillin, oxacillin, dicloxacillin
-ampicillin, amoxicillin
-piperacillin
-combo-amp/sulbactam(unasyn), amox/clav (augmentin), pip/taco (zosyn) B-lactation: cephalosporin
-cephalexin (keflex)
-cefoxitin (mefoxin)
-cefotaxime (claforan)
-cefepime (maxipime)
-ceftaroline (teflaro) Fluoroquinolones
-ciprofloxacin (cipro)
-ofloxacin (floxin)
-levofloxacin (levaquin)
-moxifloxacin (avelox) Tetracyclines and Macrolides
-tetracycline, doxycycline
-erythromycin, azithromycin(zithromax), clarithromycin (Biaxin) Sulfonamides, Trimethoprim, and
Nitrofurantoin
-sulfadiazine, sulfamethoxazole(bactrim)
-trimethoprim (primsol)
-TMP/SMZ: trimethoprim/sulfamethoxazole
-nitrofurantoin (macrodantin)
Question 2: Examples of cell wall synthesis inhibitors
Answer: penicillin, cephalosporin, imipenem, vancomycin
Question 3: What are the considerations when choosing antibiotic therapy
Answer: *The HOST
-history of allergy, cross allergy or intolerance
-preexisting conditions: HIV, cancer, autoimmune disorders, diabetes
-renal/hepatic function-cr clearance
-Age, pregnancy and lactation, recent antibiotic use, exposure history (wt based dosing for pediatric and
geriatric population) *The SYNDROME or PRESENTING ILLNESS
-what system is impacted
-how aggressive the infection
-consider non-bacterial causes
-carefully examine clinical presentation of illness *The PATHOGEN
-obtaining culture and sensitivity/resistance
-how susceptibility is determined AST/Petri dish growth
Page 1
,Question 4: When prescribing macrolides what is the patient teaching
Answer: Take with food to reduce G.I. disturbances
Question 5: Which antibiotic should have a culture done before therapy begins
Answer: Vancomyosin, Carbapenem, Penicillin
Question 6: Which antibiotics do not require a culture prior to start of therapy
Answer: Tetracyclines and macrolides
Question 7: Situations when PO or IV antibiotics should be prescribed
Answer: critical or severe infections Iv
Question 8: When can IV antibiotics be switched to PO?
Answer: WHen pt is stable
Question 9: Bactericides antibiotics
Answer: Directly kill bacteria Examples include aminoglycosides Beta lactums, Fluoroquinolones,
metronidazole, most antimycobacterial agents, streptogramins, and vancomycin
Question 10: Bacteriostatic agents
Answer: Inhibit bacterial proliferation while the hosts immune system does the killing Examples include
Clindamycin, macrolides sulfonamides and tetracyclines
Question 11: Broad-spectrum antibiotic uses
Answer: Target wider number of bacteria types Acts on both Graham negative and gram-positive
organisms Commonly used for empiric therapy when the pathogen is unknown or infection with
multiple types of bacteria and suspected
Question 12: commonly used for empiric therapy when the pathogen is unknown or infection
with multiple
Answer: types of bacteria and suspected
Question 13: Risks of using broad-spectrum antibiotics
Answer: Disruption of normal flora and development of anabiotic resistance
Page 2
, Question 14: Narrow spectrum antibiotic uses
Answer: Affective against a specific bacteria type used when infecting pathogens are known reduces
risk of disruption of normal flora and reduce development of anabiotic resistance
Question 15: What is the preferred antibiotic narrow spectrum or broad-spectrum
Answer: Narrow spectrum
Question 16: Conjunctivitis is most likely caused by which bacteria
Answer: Staphylococcus or streptococcus tx polymyxin-trimethoprim opthalamic drops for 7-10 days
Question 17: What are the causative agent of community acquired pneumonia
Answer: S. Pneumonia (gram +) mycoplasma pneumoniae (atypical pneumonia) Viruses
H. Influenzaem staphlylococcus aureus
Question 18: Therapeutic trials class used for CAP
Answer: Amoxicillin doxycycline macrolides
Question 19: Likely prescription for a CAP
Answer: Amoxicillin PO for 7 to 10 days or azithromycin PO for five days
Question 20: Tx for severe CAP
Answer: Beta-lactam and macrolide or fluroquinolone
Question 21: Likely prescription for severe CAP
Answer: Ampicillin/sulbactam IV and azithromycin IV or levofloxacin IV x 5 days
Question 22: What bacteria causes complicated and uncomplicated UTIs
Answer: E. coli
Question 23: Treatment for complicated UTI
Answer: drug class: fluroquinolones Ciprofloxacin PO for 1-2 weeks
Question 24: Uncomplicated UTI treatment
Answer: Trimethoprim-sulfamethoxazole (Bactrim) for 3 days or nitrofurantoin x 5days
Page 3
Verified Answers (Correct Update)
Question 1: Antibiotic Classes and examples of infectious disease drugs
Answer: ß-Lactams : penicillins
-Penicillin G, V
-Nafcillin, oxacillin, dicloxacillin
-ampicillin, amoxicillin
-piperacillin
-combo-amp/sulbactam(unasyn), amox/clav (augmentin), pip/taco (zosyn) B-lactation: cephalosporin
-cephalexin (keflex)
-cefoxitin (mefoxin)
-cefotaxime (claforan)
-cefepime (maxipime)
-ceftaroline (teflaro) Fluoroquinolones
-ciprofloxacin (cipro)
-ofloxacin (floxin)
-levofloxacin (levaquin)
-moxifloxacin (avelox) Tetracyclines and Macrolides
-tetracycline, doxycycline
-erythromycin, azithromycin(zithromax), clarithromycin (Biaxin) Sulfonamides, Trimethoprim, and
Nitrofurantoin
-sulfadiazine, sulfamethoxazole(bactrim)
-trimethoprim (primsol)
-TMP/SMZ: trimethoprim/sulfamethoxazole
-nitrofurantoin (macrodantin)
Question 2: Examples of cell wall synthesis inhibitors
Answer: penicillin, cephalosporin, imipenem, vancomycin
Question 3: What are the considerations when choosing antibiotic therapy
Answer: *The HOST
-history of allergy, cross allergy or intolerance
-preexisting conditions: HIV, cancer, autoimmune disorders, diabetes
-renal/hepatic function-cr clearance
-Age, pregnancy and lactation, recent antibiotic use, exposure history (wt based dosing for pediatric and
geriatric population) *The SYNDROME or PRESENTING ILLNESS
-what system is impacted
-how aggressive the infection
-consider non-bacterial causes
-carefully examine clinical presentation of illness *The PATHOGEN
-obtaining culture and sensitivity/resistance
-how susceptibility is determined AST/Petri dish growth
Page 1
,Question 4: When prescribing macrolides what is the patient teaching
Answer: Take with food to reduce G.I. disturbances
Question 5: Which antibiotic should have a culture done before therapy begins
Answer: Vancomyosin, Carbapenem, Penicillin
Question 6: Which antibiotics do not require a culture prior to start of therapy
Answer: Tetracyclines and macrolides
Question 7: Situations when PO or IV antibiotics should be prescribed
Answer: critical or severe infections Iv
Question 8: When can IV antibiotics be switched to PO?
Answer: WHen pt is stable
Question 9: Bactericides antibiotics
Answer: Directly kill bacteria Examples include aminoglycosides Beta lactums, Fluoroquinolones,
metronidazole, most antimycobacterial agents, streptogramins, and vancomycin
Question 10: Bacteriostatic agents
Answer: Inhibit bacterial proliferation while the hosts immune system does the killing Examples include
Clindamycin, macrolides sulfonamides and tetracyclines
Question 11: Broad-spectrum antibiotic uses
Answer: Target wider number of bacteria types Acts on both Graham negative and gram-positive
organisms Commonly used for empiric therapy when the pathogen is unknown or infection with
multiple types of bacteria and suspected
Question 12: commonly used for empiric therapy when the pathogen is unknown or infection
with multiple
Answer: types of bacteria and suspected
Question 13: Risks of using broad-spectrum antibiotics
Answer: Disruption of normal flora and development of anabiotic resistance
Page 2
, Question 14: Narrow spectrum antibiotic uses
Answer: Affective against a specific bacteria type used when infecting pathogens are known reduces
risk of disruption of normal flora and reduce development of anabiotic resistance
Question 15: What is the preferred antibiotic narrow spectrum or broad-spectrum
Answer: Narrow spectrum
Question 16: Conjunctivitis is most likely caused by which bacteria
Answer: Staphylococcus or streptococcus tx polymyxin-trimethoprim opthalamic drops for 7-10 days
Question 17: What are the causative agent of community acquired pneumonia
Answer: S. Pneumonia (gram +) mycoplasma pneumoniae (atypical pneumonia) Viruses
H. Influenzaem staphlylococcus aureus
Question 18: Therapeutic trials class used for CAP
Answer: Amoxicillin doxycycline macrolides
Question 19: Likely prescription for a CAP
Answer: Amoxicillin PO for 7 to 10 days or azithromycin PO for five days
Question 20: Tx for severe CAP
Answer: Beta-lactam and macrolide or fluroquinolone
Question 21: Likely prescription for severe CAP
Answer: Ampicillin/sulbactam IV and azithromycin IV or levofloxacin IV x 5 days
Question 22: What bacteria causes complicated and uncomplicated UTIs
Answer: E. coli
Question 23: Treatment for complicated UTI
Answer: drug class: fluroquinolones Ciprofloxacin PO for 1-2 weeks
Question 24: Uncomplicated UTI treatment
Answer: Trimethoprim-sulfamethoxazole (Bactrim) for 3 days or nitrofurantoin x 5days
Page 3
