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NCLEX-RN Pharmacology Practice Questions 2026 | 20 Nursing MCQs, Medication Safety & Clinical Judgment

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Prepare for NCLEX-RN Pharmacology exams with 20 original, high-quality nursing pharmacology practice questions focused on medication safety, clinical judgment, adverse effects, drug interactions, contraindications, therapeutic responses, laboratory monitoring, medication errors, high-alert medications, renal impairment, pregnancy, pediatrics, and patient teaching. Includes realistic clinical scenarios, four-option MCQs, correct answers, detailed rationales, learning objectives, and medication safety focuses. Ideal for nursing students, NCLEX-RN preparation, pharmacology review, Stuvia, and Docsity. NCLEX RN Pharmacology Questions Nursing Pharmacology Practice Questions NCLEX Pharmacology MCQs Medication Safety Nursing Pharmacology Nursing Test Bank NCLEX RN Practice Questions Nursing Pharmacology Exam Prep

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ECGs Made Easy
7th Edition
• Author(s)Barbara Aehlert
• Print ISBN: 9780323794251


Introduction to Pharmacology


Test Bank

,Question 1

Difficulty: Easy

Clinical Scenario

A 68-year-old client with newly diagnosed hypertension is prescribed a first dose of amlodipine
5 mg PO daily. During medication preparation, the nurse notices that the electronic medication
administration record lists the client's allergy section as incomplete. The client is currently
resting in bed and has no acute symptoms.

Question Stem

Which action should the nurse take before administering the medication?

A. Administer the medication because amlodipine is generally well tolerated.
B. Ask the client whether they have ever taken amlodipine before.
C. Verify the client's allergy history using the medication record and direct client questioning.
D. Ask another nurse to administer the medication instead.

Correct Answer

Correct Answer: C. Verify the client's allergy history using the medication record and direct
client questioning.

Detailed Rationale

The nurse should verify the allergy history before administering a newly prescribed medication.
Medication administration requires confirmation of the correct patient, medication, dose, route,
time, indication, and relevant safety information, including allergies. Allergy verification should
use the available health record and direct communication with the client when possible. A
complete allergy assessment can prevent potentially serious hypersensitivity reactions.

A is incorrect because a medication should never be administered simply because it is
commonly tolerated. Individual patients can experience serious reactions to medications.

B is incomplete because asking whether the client has previously taken the drug does not
establish a complete allergy history. The client could have an allergy to another medication or
excipient.

D is incorrect because delegation does not eliminate the nurse's responsibility to verify
medication safety before administration.

The nurse should also determine the type of reported reaction rather than documenting only
the word "allergy." A history of anaphylaxis, angioedema, or severe rash has different

, implications from predictable side effects such as mild dizziness. Safe pharmacologic practice
begins with patient-specific assessment rather than assumptions based on the medication's
usual safety profile.

Learning Objective

After completing this question, the learner should be able to:

• Identify allergy verification as a required component of medication safety.

• Distinguish allergy assessment from general medication-history questions.

• Apply safe medication-administration principles before the first dose.

Medication Safety Focus

Medication administration



Question 2

Difficulty: Easy

Clinical Scenario

A 57-year-old client with asthma receives an inhaled bronchodilator for acute wheezing. Before
treatment, the client has audible wheezing and a respiratory rate of 26/min. Fifteen minutes
after administration, the respiratory rate is 20/min, wheezing has decreased, and the client
reports that breathing is easier. Oxygen saturation has increased from 91% to 95% on the same
oxygen flow rate.

Question Stem

Which finding best indicates the medication produced the desired therapeutic response?

A. The client reports less difficulty breathing.
B. The client develops mild hand tremors.
C. The client reports a transient headache.
D. The client's heart rate increases from 88/min to 102/min.

Correct Answer

Correct Answer: A. The client reports less difficulty breathing.

Detailed Rationale

Connected book
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Barbara J. Aehlert ECGs Made Easy
Publisher: 2022 ISBN: 9780323794251 Edition: Unknown

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Uploaded on
September 21, 2026
Number of pages
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Type
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