COMSAE ACTUAL TEST QUESTIONS WITH
VERIFIED CORRECT ANSWERS
●● How many patients showed progression with the experimental drug
in the Alzheimer's study?
Answer: 50 patients.
●● What is the total number of patients in the Alzheimer's study?
Answer: 240 patients.
●● What calculation would best determine how many patients need to
be treated for one successful outcome in the Alzheimer's study?
Answer: [50/(50 + 70)] / [75/(75 + 45)]
●● What was the reduction in systolic blood pressure with combination
therapy compared to hydrochlorothiazide alone?
Answer: 25 mmHg (95% CI = 15-35 mmHg, p = 0.049).
●● What conclusion can be drawn from the study comparing
combination therapy to hydrochlorothiazide alone?
Answer: There is an approximate 5% probability that the decrease in
systolic blood pressure was due to chance.
,●● Which study design is most appropriate to evaluate the relationship
between nasopharyngeal cancer and exposure to wood products?
Answer: Case control study.
●● What is the strongest study design to evaluate the efficacy of yoga
for patients with ADHD?
Answer: Randomized clinical trial.
●● What was the smoking history of the 56-year-old man with a lesion
on his tongue?
Answer: A 60 pack-year history.
●● What did the 56-year-old man refuse after counseling regarding his
tongue lesion?
Answer: Further evaluation of the lesion.
●● What is the main concern of the 56-year-old man regarding his
treatment options?
Answer: He does not want 'a bunch of doctors messing' with him.
●● What is the significance of a p-value of 0.049 in the hypertension
study?
Answer: It indicates that the results are statistically significant, with a
less than 5% probability that the results are due to chance.
,●● In the study evaluating combination therapy for hypertension, what
was the control treatment?
Answer: Hydrochlorothiazide alone.
●● What type of study design is a randomized clinical trial?
Answer: A study design that randomly assigns participants to treatment
or control groups to evaluate the efficacy of interventions.
●● What is the purpose of a case control study?
Answer: To compare individuals with a specific condition to those
without the condition to identify potential risk factors.
●● What does the term 'cross-sectional study' refer to?
Answer: A study design that analyzes data from a population at a
specific point in time.
●● What is the role of a cohort study in medical research?
Answer: To follow a group of individuals over time to assess the effects
of certain exposures on outcomes.
●● What is the primary focus of an ecological study?
Answer: To examine the relationships between environmental factors
and health outcomes at a population level.
, ●● What is the significance of a 95% confidence interval in clinical
studies?
Answer: It indicates the range within which the true effect size is likely
to fall 95% of the time.
●● What does the term 'efficacy' refer to in the context of medical
treatments?
Answer: The ability of a treatment to produce a desired effect under
ideal conditions.
●● What is the importance of randomization in clinical trials?
Answer: It helps to eliminate bias and ensures that the treatment groups
are comparable.
●● What is the main outcome of interest in the study of yoga for
ADHD?
Answer: The calming effect of yoga on patients diagnosed with attention
deficit hyperactivity disorder.
●● What is the significance of a 'double-blind' study design?
Answer: Neither the participants nor the researchers know who is
receiving the treatment or the placebo, reducing bias.
VERIFIED CORRECT ANSWERS
●● How many patients showed progression with the experimental drug
in the Alzheimer's study?
Answer: 50 patients.
●● What is the total number of patients in the Alzheimer's study?
Answer: 240 patients.
●● What calculation would best determine how many patients need to
be treated for one successful outcome in the Alzheimer's study?
Answer: [50/(50 + 70)] / [75/(75 + 45)]
●● What was the reduction in systolic blood pressure with combination
therapy compared to hydrochlorothiazide alone?
Answer: 25 mmHg (95% CI = 15-35 mmHg, p = 0.049).
●● What conclusion can be drawn from the study comparing
combination therapy to hydrochlorothiazide alone?
Answer: There is an approximate 5% probability that the decrease in
systolic blood pressure was due to chance.
,●● Which study design is most appropriate to evaluate the relationship
between nasopharyngeal cancer and exposure to wood products?
Answer: Case control study.
●● What is the strongest study design to evaluate the efficacy of yoga
for patients with ADHD?
Answer: Randomized clinical trial.
●● What was the smoking history of the 56-year-old man with a lesion
on his tongue?
Answer: A 60 pack-year history.
●● What did the 56-year-old man refuse after counseling regarding his
tongue lesion?
Answer: Further evaluation of the lesion.
●● What is the main concern of the 56-year-old man regarding his
treatment options?
Answer: He does not want 'a bunch of doctors messing' with him.
●● What is the significance of a p-value of 0.049 in the hypertension
study?
Answer: It indicates that the results are statistically significant, with a
less than 5% probability that the results are due to chance.
,●● In the study evaluating combination therapy for hypertension, what
was the control treatment?
Answer: Hydrochlorothiazide alone.
●● What type of study design is a randomized clinical trial?
Answer: A study design that randomly assigns participants to treatment
or control groups to evaluate the efficacy of interventions.
●● What is the purpose of a case control study?
Answer: To compare individuals with a specific condition to those
without the condition to identify potential risk factors.
●● What does the term 'cross-sectional study' refer to?
Answer: A study design that analyzes data from a population at a
specific point in time.
●● What is the role of a cohort study in medical research?
Answer: To follow a group of individuals over time to assess the effects
of certain exposures on outcomes.
●● What is the primary focus of an ecological study?
Answer: To examine the relationships between environmental factors
and health outcomes at a population level.
, ●● What is the significance of a 95% confidence interval in clinical
studies?
Answer: It indicates the range within which the true effect size is likely
to fall 95% of the time.
●● What does the term 'efficacy' refer to in the context of medical
treatments?
Answer: The ability of a treatment to produce a desired effect under
ideal conditions.
●● What is the importance of randomization in clinical trials?
Answer: It helps to eliminate bias and ensures that the treatment groups
are comparable.
●● What is the main outcome of interest in the study of yoga for
ADHD?
Answer: The calming effect of yoga on patients diagnosed with attention
deficit hyperactivity disorder.
●● What is the significance of a 'double-blind' study design?
Answer: Neither the participants nor the researchers know who is
receiving the treatment or the placebo, reducing bias.
