CPJE PRACTICE | 2026/2027 | CALIFORNIA PHARMACY JURISPRUDENCE EXAM | COMPREHENSIVE…
P R O F E S S I O N A L P R A C T I C E M AT E R I A L S
CPJE Practice | 2026/2027 |
California Pharmacy
Jurisprudence Exam |
Comprehensive Review |
Questions & Answers
(Rationales)
Verified Answers Exam Ready With Rationales 92 QUESTIONS
DOCUMENT OVERVIEW
This comprehensive review document contains 92 practice questions with pre-provided
correct answers and detailed rationales, focusing on California Pharmacy Jurisprudence. It
is designed for effective study and review, directly aligning with preparation for the CPJE
certification exam.
TOPICS
Prescription Management & Dispensing Q1–Q48
Drug Specifics & Interactions Q49–Q71
Patient Assessment & Understanding Q72–Q87
Formulation & Preparation Q88–Q89
Therapeutic Monitoring & Protocols Q90–Q92
Page 1
, E XA M Q U EST I O N S
Q1 QUESTION 1 OF 92
A pharmacist is counseling a 58-year-old man with a new prescription for repaglinide 0.5
mg t.i.d. According to the patient profile, he is homeless. Which of the following information
should be requested from the patient and what is the rationale?
RESPONSE
Are you eating three regular meals per day? Drug is taken with meals and skipped if meal is
skipped.
RATIONALE
Repaglinide is an insulin secretagogue that requires administration with meals to effectively lower
postprandial glucose. Its efficacy and safety are directly tied to meal consumption. Therefore,
confirming the patient's meal schedule is essential for appropriate dosing and to prevent
hypoglycemia.
Q2 QUESTION 2 OF 92
What could be considered barriers to providing a thorough oral consultation to a patient?
RESPONSE
Educational Background.
Primary language.
Physical Impairment.
RATIONALE
A patient's educational background influences their comprehension of health information.
Differences in primary language can impede effective communication. Additionally, physical
impairments may affect a patient's ability to participate in or understand an oral consultation.
Page 2
, Q3 QUESTION 3 OF 92
A hospital pharmacist has just received a new medication order for brimonidine. The
pharmacist wishes to confirm the appropriateness of this order and calls the nurse for the
patient's diagnosis. What diagnoses would confirm that the brimonidine order is
APPROPRIATE?
RESPONSE
Glaucoma
RATIONALE
Brimonidine is an alpha-adrenergic agonist primarily used for its ophthalmic effects. Its mechanism
involves reducing intraocular pressure by decreasing aqueous humor production and increasing
uveoscleral outflow. Therefore, a diagnosis of glaucoma is an appropriate indication for its use.
Q4 QUESTION 4 OF 92
A physician writes the following prescription: Finasteride 1 mg tablets #30
1 tab p.o. daily for benign prostatic hyperplasia
What would be the MOST APPROPRIATE action of the pharmacist?
RESPONSE
Call physician regarding dosage strength.
RATIONALE
Finasteride is indicated for benign prostatic hyperplasia (BPH) at a dosage of 5 mg daily, not 1 mg.
The prescribed 1 mg strength is typically used for male pattern hair loss. Therefore, the pharmacist
must verify the correct dosage strength with the prescriber for the intended indication.
Q5 QUESTION 5 OF 92
Which of the following is CORRECT about a prescription for naproxen sodium 275 mg
tablets #20 Sig: i tab b.i.d.?
A. Naproxen sodium at that dosage may be sold without a prescription as a product called
Aleve®.
B. The prescription may be filled as written.
C. The prescription may be filled with Naprosyn® if Anaprox® is not available.
D. Naproxen sodium at that dosage should not be given b.i.d.
Page 3
, RESPONSE
B. Fill as written.
RATIONALE
A prescription for naproxen sodium 275 mg tablets for a specified quantity and sig is a valid
prescription that a pharmacist is authorized to dispense. The dosage and instructions provided are
standard for this medication. Therefore, the prescription can be accurately filled as written by the
prescriber.
Q6 QUESTION 6 OF 92
The pharmacist receives a telephone prescription for testosterone patches from a
physician's nurse. Assuming that the dosage, quantity, and instructions are appropriate, and
the prescription is reduced to writing, the pharmacist should
RESPONSE
Fill the prescription after noting the physician's and the nurse's names on the prescription.
RATIONALE
California law permits pharmacists to fill telephone prescriptions for controlled substances and
dangerous drugs when reduced to writing. Documentation must include the prescribing
physician's name and the identity of the registered nurse who communicated the order. This
practice ensures accountability and adherence to regulatory requirements for valid prescriptions.
Q7 QUESTION 7 OF 92
A pharmacist receives a security prescription from a known local medical group for
promethazine with codeine. The prescription blank has the physician's name, address,
phone number, DEA number, and license number, but is signed only by a physician's
assistant (PA). The pharmacist's best course of action is to
RESPONSE
Call the medical group and request the PA's DEA number.
Page 4
P R O F E S S I O N A L P R A C T I C E M AT E R I A L S
CPJE Practice | 2026/2027 |
California Pharmacy
Jurisprudence Exam |
Comprehensive Review |
Questions & Answers
(Rationales)
Verified Answers Exam Ready With Rationales 92 QUESTIONS
DOCUMENT OVERVIEW
This comprehensive review document contains 92 practice questions with pre-provided
correct answers and detailed rationales, focusing on California Pharmacy Jurisprudence. It
is designed for effective study and review, directly aligning with preparation for the CPJE
certification exam.
TOPICS
Prescription Management & Dispensing Q1–Q48
Drug Specifics & Interactions Q49–Q71
Patient Assessment & Understanding Q72–Q87
Formulation & Preparation Q88–Q89
Therapeutic Monitoring & Protocols Q90–Q92
Page 1
, E XA M Q U EST I O N S
Q1 QUESTION 1 OF 92
A pharmacist is counseling a 58-year-old man with a new prescription for repaglinide 0.5
mg t.i.d. According to the patient profile, he is homeless. Which of the following information
should be requested from the patient and what is the rationale?
RESPONSE
Are you eating three regular meals per day? Drug is taken with meals and skipped if meal is
skipped.
RATIONALE
Repaglinide is an insulin secretagogue that requires administration with meals to effectively lower
postprandial glucose. Its efficacy and safety are directly tied to meal consumption. Therefore,
confirming the patient's meal schedule is essential for appropriate dosing and to prevent
hypoglycemia.
Q2 QUESTION 2 OF 92
What could be considered barriers to providing a thorough oral consultation to a patient?
RESPONSE
Educational Background.
Primary language.
Physical Impairment.
RATIONALE
A patient's educational background influences their comprehension of health information.
Differences in primary language can impede effective communication. Additionally, physical
impairments may affect a patient's ability to participate in or understand an oral consultation.
Page 2
, Q3 QUESTION 3 OF 92
A hospital pharmacist has just received a new medication order for brimonidine. The
pharmacist wishes to confirm the appropriateness of this order and calls the nurse for the
patient's diagnosis. What diagnoses would confirm that the brimonidine order is
APPROPRIATE?
RESPONSE
Glaucoma
RATIONALE
Brimonidine is an alpha-adrenergic agonist primarily used for its ophthalmic effects. Its mechanism
involves reducing intraocular pressure by decreasing aqueous humor production and increasing
uveoscleral outflow. Therefore, a diagnosis of glaucoma is an appropriate indication for its use.
Q4 QUESTION 4 OF 92
A physician writes the following prescription: Finasteride 1 mg tablets #30
1 tab p.o. daily for benign prostatic hyperplasia
What would be the MOST APPROPRIATE action of the pharmacist?
RESPONSE
Call physician regarding dosage strength.
RATIONALE
Finasteride is indicated for benign prostatic hyperplasia (BPH) at a dosage of 5 mg daily, not 1 mg.
The prescribed 1 mg strength is typically used for male pattern hair loss. Therefore, the pharmacist
must verify the correct dosage strength with the prescriber for the intended indication.
Q5 QUESTION 5 OF 92
Which of the following is CORRECT about a prescription for naproxen sodium 275 mg
tablets #20 Sig: i tab b.i.d.?
A. Naproxen sodium at that dosage may be sold without a prescription as a product called
Aleve®.
B. The prescription may be filled as written.
C. The prescription may be filled with Naprosyn® if Anaprox® is not available.
D. Naproxen sodium at that dosage should not be given b.i.d.
Page 3
, RESPONSE
B. Fill as written.
RATIONALE
A prescription for naproxen sodium 275 mg tablets for a specified quantity and sig is a valid
prescription that a pharmacist is authorized to dispense. The dosage and instructions provided are
standard for this medication. Therefore, the prescription can be accurately filled as written by the
prescriber.
Q6 QUESTION 6 OF 92
The pharmacist receives a telephone prescription for testosterone patches from a
physician's nurse. Assuming that the dosage, quantity, and instructions are appropriate, and
the prescription is reduced to writing, the pharmacist should
RESPONSE
Fill the prescription after noting the physician's and the nurse's names on the prescription.
RATIONALE
California law permits pharmacists to fill telephone prescriptions for controlled substances and
dangerous drugs when reduced to writing. Documentation must include the prescribing
physician's name and the identity of the registered nurse who communicated the order. This
practice ensures accountability and adherence to regulatory requirements for valid prescriptions.
Q7 QUESTION 7 OF 92
A pharmacist receives a security prescription from a known local medical group for
promethazine with codeine. The prescription blank has the physician's name, address,
phone number, DEA number, and license number, but is signed only by a physician's
assistant (PA). The pharmacist's best course of action is to
RESPONSE
Call the medical group and request the PA's DEA number.
Page 4
