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ATI_RN_Comprehensive_Online_Practice_2026_A_B_300_Questions

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This ATI RN Comprehensive Online Practice resource contains 300 questions designed to build mastery of nursing knowledge and clinical judgment. Content covers fundamentals, medical-surgical nursing, pharmacology, maternal newborn care, pediatric nursing, mental health, leadership, delegation, prioritization, and patient safety. Questions encourage application of nursing concepts to realistic clinical situations while strengthening assessment, decision-making, critical thinking, medication safety, and patient education. Practice supports recognition of urgent findings and nursing interventions. Comprehensive rationales reinforce clinical reasoning, clarify difficult concepts, and help learners identify knowledge gaps. The resource provides preparation for ATI assessments and NCLEX-RN-style examinations while strengthening confidence in professional nursing practice.

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ATI RN Comprehensive Online Practice 2026 A & B
300 Practice Questions with Detailed Rationales
Original ATI/NCLEX-style study material — not copied from ATI proprietary assessments. Designed for comprehensive RN
review with emphasis on clinical judgment, prioritization, safety, and core nursing content.

Color key: Questions = blue Choices = black Correct answer = green Rationale = brown


1. [Fundamentals] A nurse is reviewing this situation during routine client care. which action is essential before
administering a medication?
A. Compare the medication label with the MAR at the bedside
B. Ask whether the client likes the medication
C. Document administration before giving it
D. Leave the medication at the bedside
Correct answer: A. Compare the medication label with the MAR at the bedside
Rationale: Comparing the label with the MAR is a core medication-safety check.

2. [Fundamentals] During a focused assessment, which action is essential before administering a medication?
A. Compare the medication label with the MAR at the bedside
B. Ask whether the client likes the medication
C. Document administration before giving it
D. Leave the medication at the bedside
Correct answer: A. Compare the medication label with the MAR at the bedside
Rationale: Comparing the label with the MAR is a core medication-safety check.

3. [Fundamentals] While planning the next nursing action, which action is essential before administering a
medication?
A. Compare the medication label with the MAR at the bedside
B. Ask whether the client likes the medication
C. Document administration before giving it
D. Leave the medication at the bedside
Correct answer: A. Compare the medication label with the MAR at the bedside
Rationale: Comparing the label with the MAR is a core medication-safety check.

4. [Fundamentals] During a shift handoff and reassessment, which action is essential before administering a
medication?
A. Compare the medication label with the MAR at the bedside
B. Ask whether the client likes the medication
C. Document administration before giving it
D. Leave the medication at the bedside
Correct answer: A. Compare the medication label with the MAR at the bedside
Rationale: Comparing the label with the MAR is a core medication-safety check.




ATI RN Comprehensive Online Practice 2026 A & B — Original practice bank Page 1

, 5. [Fundamentals] When preparing for safe client care, which action is essential before administering a medication?
A. Compare the medication label with the MAR at the bedside
B. Ask whether the client likes the medication
C. Document administration before giving it
D. Leave the medication at the bedside
Correct answer: A. Compare the medication label with the MAR at the bedside
Rationale: Comparing the label with the MAR is a core medication-safety check.

6. [Fundamentals] During an exam-style clinical judgment review, which action is essential before administering a
medication?
A. Compare the medication label with the MAR at the bedside
B. Ask whether the client likes the medication
C. Document administration before giving it
D. Leave the medication at the bedside
Correct answer: A. Compare the medication label with the MAR at the bedside
Rationale: Comparing the label with the MAR is a core medication-safety check.

7. [Fundamentals] A nurse is reviewing this situation during routine client care. which intervention is appropriate for
a client at high risk for falls?
A. Keep the bed in the lowest position
B. Raise all four side rails
C. Apply a vest restraint routinely
D. Keep the client on strict bed rest
Correct answer: A. Keep the bed in the lowest position
Rationale: A low bed reduces fall injury risk while preserving mobility.

8. [Fundamentals] During a focused assessment, which intervention is appropriate for a client at high risk for falls?
A. Keep the bed in the lowest position
B. Raise all four side rails
C. Apply a vest restraint routinely
D. Keep the client on strict bed rest
Correct answer: A. Keep the bed in the lowest position
Rationale: A low bed reduces fall injury risk while preserving mobility.

9. [Fundamentals] While planning the next nursing action, which intervention is appropriate for a client at high risk
for falls?
A. Keep the bed in the lowest position
B. Raise all four side rails
C. Apply a vest restraint routinely
D. Keep the client on strict bed rest
Correct answer: A. Keep the bed in the lowest position
Rationale: A low bed reduces fall injury risk while preserving mobility.




ATI RN Comprehensive Online Practice 2026 A & B — Original practice bank Page 2

, 10. [Fundamentals] During a shift handoff and reassessment, which intervention is appropriate for a client at high
risk for falls?
A. Keep the bed in the lowest position
B. Raise all four side rails
C. Apply a vest restraint routinely
D. Keep the client on strict bed rest
Correct answer: A. Keep the bed in the lowest position
Rationale: A low bed reduces fall injury risk while preserving mobility.

11. [Fundamentals] When preparing for safe client care, which intervention is appropriate for a client at high risk for
falls?
A. Keep the bed in the lowest position
B. Raise all four side rails
C. Apply a vest restraint routinely
D. Keep the client on strict bed rest
Correct answer: A. Keep the bed in the lowest position
Rationale: A low bed reduces fall injury risk while preserving mobility.

12. [Fundamentals] During an exam-style clinical judgment review, which intervention is appropriate for a client at
high risk for falls?
A. Keep the bed in the lowest position
B. Raise all four side rails
C. Apply a vest restraint routinely
D. Keep the client on strict bed rest
Correct answer: A. Keep the bed in the lowest position
Rationale: A low bed reduces fall injury risk while preserving mobility.

13. [Fundamentals] A nurse is reviewing this situation during routine client care. which finding should the nurse
report immediately in a client receiving oxygen?
A. New confusion and increasing restlessness
B. Mild nasal dryness
C. A request for a different pillow
D. Slight thirst
Correct answer: A. New confusion and increasing restlessness
Rationale: New confusion and restlessness can indicate worsening hypoxemia.




ATI RN Comprehensive Online Practice 2026 A & B — Original practice bank Page 3

, 14. [Fundamentals] During a focused assessment, which finding should the nurse report immediately in a client
receiving oxygen?
A. New confusion and increasing restlessness
B. Mild nasal dryness
C. A request for a different pillow
D. Slight thirst
Correct answer: A. New confusion and increasing restlessness
Rationale: New confusion and restlessness can indicate worsening hypoxemia.

15. [Fundamentals] While planning the next nursing action, which finding should the nurse report immediately in a
client receiving oxygen?
A. New confusion and increasing restlessness
B. Mild nasal dryness
C. A request for a different pillow
D. Slight thirst
Correct answer: A. New confusion and increasing restlessness
Rationale: New confusion and restlessness can indicate worsening hypoxemia.

16. [Fundamentals] During a shift handoff and reassessment, which finding should the nurse report immediately in a
client receiving oxygen?
A. New confusion and increasing restlessness
B. Mild nasal dryness
C. A request for a different pillow
D. Slight thirst
Correct answer: A. New confusion and increasing restlessness
Rationale: New confusion and restlessness can indicate worsening hypoxemia.

17. [Fundamentals] When preparing for safe client care, which finding should the nurse report immediately in a
client receiving oxygen?
A. New confusion and increasing restlessness
B. Mild nasal dryness
C. A request for a different pillow
D. Slight thirst
Correct answer: A. New confusion and increasing restlessness
Rationale: New confusion and restlessness can indicate worsening hypoxemia.




ATI RN Comprehensive Online Practice 2026 A & B — Original practice bank Page 4

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September 21, 2026
Number of pages
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