PORTH'S ESSENTIALS OF PATHOPHYSIOLOGY
5TH EDITION BY NORRIS COMPREHENSIVE
EXAM SCRIPT WITH SOLUTIONS
◉ Disorders affecting the nerve cell body are often referred to as ? ;
those affecting the nerve axon, as ? neuropathies; and primary
disorders affecting the muscle fibers as ?.
Answer: Lower motor neuron disorders, peripheral, myopathies
◉ Muscular ? is a term applied to a number of genetic disorders that
produce progressive deteriorations of skeletal muscles because of
mixed muscle cell hypertrophy, atrophy, and necrosis.
Answer: dystrophy
◉ If the lower motor neuron dies or its axon is destroyed, the
skeletal muscle cell beings to have temporary spontaneous
contractions called ?.
Answer: fasciculations
◉ ? muscle dystrophy is inherited as a recessive single-gene defect
on the X chromosome and is transmitted from the mother to her
male offspring.
, Answer: Duchenne
◉ The ? serves as a synapse between a motor neuron and a skeletal
muscle fiber.
Answer: neuromuscular junction
◉ Neurotoxins from the botulism organism (C. botulinum) produce
paralysis by blocking ? release.
Answer: acetylcholine
◉ ? is a disorder of transmission at the neuromuscular junction that
affects communication between the motor neuron and the
innervated muscle cell.
Answer: Myasthenia gravis
◉ Lower motor neuron diseases are progressive neurologic illnesses
that selectively affect the anterior horn cells of the ? and ? motor
neurons.
Answer: spinal cord, cranial nerve
◉ There are two main types of ? injury based on the target of the
insult; segmental demyelination involving the Schwann cell and
axonal degeneration involving the neuronal cell body and /or its
axon.
5TH EDITION BY NORRIS COMPREHENSIVE
EXAM SCRIPT WITH SOLUTIONS
◉ Disorders affecting the nerve cell body are often referred to as ? ;
those affecting the nerve axon, as ? neuropathies; and primary
disorders affecting the muscle fibers as ?.
Answer: Lower motor neuron disorders, peripheral, myopathies
◉ Muscular ? is a term applied to a number of genetic disorders that
produce progressive deteriorations of skeletal muscles because of
mixed muscle cell hypertrophy, atrophy, and necrosis.
Answer: dystrophy
◉ If the lower motor neuron dies or its axon is destroyed, the
skeletal muscle cell beings to have temporary spontaneous
contractions called ?.
Answer: fasciculations
◉ ? muscle dystrophy is inherited as a recessive single-gene defect
on the X chromosome and is transmitted from the mother to her
male offspring.
, Answer: Duchenne
◉ The ? serves as a synapse between a motor neuron and a skeletal
muscle fiber.
Answer: neuromuscular junction
◉ Neurotoxins from the botulism organism (C. botulinum) produce
paralysis by blocking ? release.
Answer: acetylcholine
◉ ? is a disorder of transmission at the neuromuscular junction that
affects communication between the motor neuron and the
innervated muscle cell.
Answer: Myasthenia gravis
◉ Lower motor neuron diseases are progressive neurologic illnesses
that selectively affect the anterior horn cells of the ? and ? motor
neurons.
Answer: spinal cord, cranial nerve
◉ There are two main types of ? injury based on the target of the
insult; segmental demyelination involving the Schwann cell and
axonal degeneration involving the neuronal cell body and /or its
axon.
