TESTBANK
GeneticsEssentials:ConceptsandConnections 5thEditionby
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BenjaminA.Pierce
www.PlusBay.Plus
,TABLEOFCONTENT
Chapter 01: Introduction to Genetics ...................................................................................................................... 3
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Chapter 02: Chromosomes and Cellular Reproduction ......................................................................................... 15
t7 t7 t7 t7 t7
Chapter 03: Basic Principles of Heredity .............................................................................................................. 32
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Chapter 04: Extensions and Modifications of Basic Principles ............................................................................ 59
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Chapter 05: Linkage, Recombination, and Eukaryotic Gene Mapping ................................................................. 98
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Chapter 06: Chromosome Variation ................................................................................................................... 115
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Chapter 07: Bacterial and Viral Genetic Systems ............................................................................................ 139
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Chapter 08 DNA: The Chemical Nature of the Gene ........................................................................................ 152
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Chapter 09: DNA Replication and Recombination ............................................................................................. 181
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Chapter 10: From DNA to Proteins: Transcription and RNA Processing ......................................................... 198
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Chapter 11: From DNA to Proteins: Translation ............................................................................................... 224
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Chapter 12: Control of Gene Expression ............................................................................................................ 244
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Chapter 13: Gene Mutations, Transposable Elements, and DNA Repair.......................................................... 278
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Chapter14: Molecular Genetic Analysis and Biotechnology ............................................................................. 298
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Chapter 15: Genomics and Proteomics .............................................................................................................. 314
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Chapter 16: Cancer Genetics ............................................................................................................................... 332
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Chapter 17: Quantitative Genetics ....................................................................................................................... 346
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Chapter 18: Population and Evolutionary Genetics ........................................................................................... 366
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,Chapter 01: Introduction to Genetics
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1. Albinism is rare in most human populations, occurring at a frequency of about 1 in 20,000 people. Howev e
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
r, the trait occurs at a frequency of 1 in 200 in certain Hopi villages of Black Mesa in Arizona. Explain in ter m
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
s of natural selection why albinism is so rare in most human populations.
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ANSWER: In most populations, there is fairly strong selection against albinism because albinos don’t produce m
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t
e lanin, causing their skin cells not to be protected from the damaging effects of sunlight. Als
7 t7 t7 t7 t7 t7 t7 vt 7 t7 t7 t7 t7 t7 t7 t7 t7 t7
o, th e la c k of melanin in their eyes causes them to have poor eyesight. Finally, in most cultu
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
res albin os are s e en as abnormal, and they are not normally sought out for marriage and mati
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
ng. Therefor e, in most po pulations the alleles that cause albinism are selected against, and they dec
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
rease in fre quency or are ke pt at a low level, causing the recessive trait to be rare.
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
2. Albinism is rare in most human populations, occurring at a frequency of about 1 in 20,000 people. Howev e
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
r, the trait occurs at a frequency of 1 in 200 in certain Hopi villages of Black Mesa in Arizona. Explain in ter m
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
s of natural selection why the trait is so much more common among the Hopis of Black Mesa.
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
ANSWER: Albinos occupy a privileged position among the Hopis of Black Mesa. In this culture, albinos a
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
re viewed as especially pretty, clean, and intelligent, and they often occupy positions of leader s
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
hip. Albinos are celebrated in the villages as a sign of purity of Hopi blood in the comm
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
uni ty. t7
Furthermore, albinos are often excused from normal male field labor because of their sensitivity tot7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
s unlight, causing them to be left behind in the village with the women during the daytime.
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t
Thi s allo ws them extra mating opportunities compared to the other men of the village. Therefo
7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
re, t he alleles that cause albinism are either selected for in this culture or at least not selected ag
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
ainst as strongly a s in other cultures, allowing the trait to occur at a much higher frequen
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
cy.
3. Which oneof the following pairings between the subdiscipline of genetics and the phenomenon is I
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NCORRECT?
a. evolution—population genetics t7
b. gene regulation—molecular genetics
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c. allelic frequency alteration—population genetics
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d. arrangement of genes on chromosome—transmission genetics t7 t7 t7 t7 t7
e. chemical nature of the gene—transmission genetics t7 t7 t7 t7 t7
ANSWER: e t7
4. Which one of the following topics of research belongs to the discipline of transmissiongenetics?
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a. inheritance pattern of gene alleles t7 t7 t7 t7
b. mechanism of DNA replication t7 t7 t7
c. gene expression patterns t7 t7
d. evolution
e. chemical modification of nucleic acids t7 t7 t7 t7
ANSWER: a t7
5. The complete genetic makeup of an organism is referred to as its
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
a. chromosome.
b. alleles.
c. locus.
www.PlusBay.Plus
, d. genome.
e. phenotype.
ANSWER: d t7
6. Identify a TRUE statement from the following descriptions concerning genetics.
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a. The theory of pangenesis states that all living organisms are composed of cells.
t7 t7 t7 t 7 t7 t7 t7 t7 t7 t7 t7 t7
b. Bacteria and viruses are not useful in studying genes and inheritance because they are structurall
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
y and metabolically different from eukaryotic cells.
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c. Charles Darwin accurately described the laws ofinheritance in his landmark book, On theOrigin of S p
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
ecies.
d. Many human traits, such as skin and hair color, are determined by more than a singlegene.
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e. Evolution can occur without genetic changes in the population.
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ANSWER: d t7
7. Identify a FALSE statement from the following descriptions of genetics.
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a. Humans first applied genetics to the domesticationof plants and animals between approximately
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1 0,000 and 12,000 years ago.
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b. Some viruses use RNA to carry their geneticinformation.
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c. Albinism results from a mutation in the genes that control the synthesis and storage ofmelanin.
t7 t7 t7 v# t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
d. All human traits that display blending inheritance are affected by a single gene.
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e. Theprocess by which genetic information is copied and decoded is similar for all forms oflife.
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ANSWER: d t7
8. Which of the following species is considered a model genetic organism?
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a. the plant Linaria vulgaris
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b. the deer mouse Peromyscus maniculatus
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c. the worm Caenorhabditis elegans
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d. the frog Hyla chrysoscelis
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e. thechimpanzeePantroglodytes
ANSWER: c
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9. Which of the following would serve the LEAST well as a model for understanding basic mechanisms of i
t7 t7 t7 b3 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
nheritance?
a. fruit flies t7
b. humans
c. yeast
d. mice
e. zebrafish
ANSWER: b t7
10. Which of the following statements is TRUE?
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a. Each subdiscipline of genetics is very specific as to what is explored and does not overlap withthe
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
www.PlusBay.Plus
GeneticsEssentials:ConceptsandConnections 5thEditionby
t7
BenjaminA.Pierce
www.PlusBay.Plus
,TABLEOFCONTENT
Chapter 01: Introduction to Genetics ...................................................................................................................... 3
t7 t7 t7 t7
Chapter 02: Chromosomes and Cellular Reproduction ......................................................................................... 15
t7 t7 t7 t7 t7
Chapter 03: Basic Principles of Heredity .............................................................................................................. 32
t7 t7 t7 t7 t7
Chapter 04: Extensions and Modifications of Basic Principles ............................................................................ 59
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Chapter 05: Linkage, Recombination, and Eukaryotic Gene Mapping ................................................................. 98
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Chapter 06: Chromosome Variation ................................................................................................................... 115
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Chapter 07: Bacterial and Viral Genetic Systems ............................................................................................ 139
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Chapter 08 DNA: The Chemical Nature of the Gene ........................................................................................ 152
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Chapter 09: DNA Replication and Recombination ............................................................................................. 181
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Chapter 10: From DNA to Proteins: Transcription and RNA Processing ......................................................... 198
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Chapter 11: From DNA to Proteins: Translation ............................................................................................... 224
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Chapter 12: Control of Gene Expression ............................................................................................................ 244
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Chapter 13: Gene Mutations, Transposable Elements, and DNA Repair.......................................................... 278
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Chapter14: Molecular Genetic Analysis and Biotechnology ............................................................................. 298
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Chapter 15: Genomics and Proteomics .............................................................................................................. 314
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Chapter 16: Cancer Genetics ............................................................................................................................... 332
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Chapter 17: Quantitative Genetics ....................................................................................................................... 346
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Chapter 18: Population and Evolutionary Genetics ........................................................................................... 366
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www.PlusBay.Plus
,Chapter 01: Introduction to Genetics
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1. Albinism is rare in most human populations, occurring at a frequency of about 1 in 20,000 people. Howev e
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
r, the trait occurs at a frequency of 1 in 200 in certain Hopi villages of Black Mesa in Arizona. Explain in ter m
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
s of natural selection why albinism is so rare in most human populations.
t7 t7 t 7 t 7 t 7 t7 t7 t7 t7 t 7 t7 t 7
ANSWER: In most populations, there is fairly strong selection against albinism because albinos don’t produce m
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t
e lanin, causing their skin cells not to be protected from the damaging effects of sunlight. Als
7 t7 t7 t7 t7 t7 t7 vt 7 t7 t7 t7 t7 t7 t7 t7 t7 t7
o, th e la c k of melanin in their eyes causes them to have poor eyesight. Finally, in most cultu
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
res albin os are s e en as abnormal, and they are not normally sought out for marriage and mati
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
ng. Therefor e, in most po pulations the alleles that cause albinism are selected against, and they dec
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
rease in fre quency or are ke pt at a low level, causing the recessive trait to be rare.
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
2. Albinism is rare in most human populations, occurring at a frequency of about 1 in 20,000 people. Howev e
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
r, the trait occurs at a frequency of 1 in 200 in certain Hopi villages of Black Mesa in Arizona. Explain in ter m
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
s of natural selection why the trait is so much more common among the Hopis of Black Mesa.
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
ANSWER: Albinos occupy a privileged position among the Hopis of Black Mesa. In this culture, albinos a
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
re viewed as especially pretty, clean, and intelligent, and they often occupy positions of leader s
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
hip. Albinos are celebrated in the villages as a sign of purity of Hopi blood in the comm
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
uni ty. t7
Furthermore, albinos are often excused from normal male field labor because of their sensitivity tot7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
s unlight, causing them to be left behind in the village with the women during the daytime.
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t
Thi s allo ws them extra mating opportunities compared to the other men of the village. Therefo
7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
re, t he alleles that cause albinism are either selected for in this culture or at least not selected ag
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
ainst as strongly a s in other cultures, allowing the trait to occur at a much higher frequen
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
cy.
3. Which oneof the following pairings between the subdiscipline of genetics and the phenomenon is I
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 b3 t7 t7 t7 t7
NCORRECT?
a. evolution—population genetics t7
b. gene regulation—molecular genetics
t7 t7
c. allelic frequency alteration—population genetics
t7 t7 t7
d. arrangement of genes on chromosome—transmission genetics t7 t7 t7 t7 t7
e. chemical nature of the gene—transmission genetics t7 t7 t7 t7 t7
ANSWER: e t7
4. Which one of the following topics of research belongs to the discipline of transmissiongenetics?
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a. inheritance pattern of gene alleles t7 t7 t7 t7
b. mechanism of DNA replication t7 t7 t7
c. gene expression patterns t7 t7
d. evolution
e. chemical modification of nucleic acids t7 t7 t7 t7
ANSWER: a t7
5. The complete genetic makeup of an organism is referred to as its
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
a. chromosome.
b. alleles.
c. locus.
www.PlusBay.Plus
, d. genome.
e. phenotype.
ANSWER: d t7
6. Identify a TRUE statement from the following descriptions concerning genetics.
t7 vt7 t7 t7 t7 t7 t7 t7 t7
a. The theory of pangenesis states that all living organisms are composed of cells.
t7 t7 t7 t 7 t7 t7 t7 t7 t7 t7 t7 t7
b. Bacteria and viruses are not useful in studying genes and inheritance because they are structurall
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
y and metabolically different from eukaryotic cells.
t7 t7 t7 t7 t7 t7
c. Charles Darwin accurately described the laws ofinheritance in his landmark book, On theOrigin of S p
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
ecies.
d. Many human traits, such as skin and hair color, are determined by more than a singlegene.
t7 t 7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
e. Evolution can occur without genetic changes in the population.
t7 t7 t7 t7 t7 t7 vt7 t7
ANSWER: d t7
7. Identify a FALSE statement from the following descriptions of genetics.
t7 t7 t7 t7 t7 t7 t7 t7 t7
a. Humans first applied genetics to the domesticationof plants and animals between approximately
t7 t7 v# t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
1 0,000 and 12,000 years ago.
t7 t7 t7 t7 t7
b. Some viruses use RNA to carry their geneticinformation.
t7 t7 t7 t7 t7 t7 t7
c. Albinism results from a mutation in the genes that control the synthesis and storage ofmelanin.
t7 t7 t7 v# t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
d. All human traits that display blending inheritance are affected by a single gene.
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
e. Theprocess by which genetic information is copied and decoded is similar for all forms oflife.
t7 t7 t7 t7 t7 t7 t7 vt 7 t7 t7 t7 t7 t7 t7
ANSWER: d t7
8. Which of the following species is considered a model genetic organism?
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a. the plant Linaria vulgaris
t7 t7 t7
b. the deer mouse Peromyscus maniculatus
t7 t7 t7 t7
c. the worm Caenorhabditis elegans
t7 t7 t7
d. the frog Hyla chrysoscelis
t7 t7 t7
e. thechimpanzeePantroglodytes
ANSWER: c
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9. Which of the following would serve the LEAST well as a model for understanding basic mechanisms of i
t7 t7 t7 b3 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
nheritance?
a. fruit flies t7
b. humans
c. yeast
d. mice
e. zebrafish
ANSWER: b t7
10. Which of the following statements is TRUE?
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a. Each subdiscipline of genetics is very specific as to what is explored and does not overlap withthe
t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7 t7
www.PlusBay.Plus