A4M 2026 Exam Latest 2026 Updated Questions and Verified
100% Solutions (2026/2027) Grade: A+|Status: Guaranteed
Pass) – A4M001 Endocrinology, Cardiology & Neurology Q&A –
American Academy of Anti-Aging Medicine
What is the endopat test? - Answers -Endopat is a measure of endothelial function. Endopat
measures the vascular flow in a patient's arm after occlusion. Post occlusion dilation should be
greater in the control arm due to release of NO.
Sensitivity of SPECT scan for diagnosing Alzheimer's dz - Answers -74%
Medications that decrease conversion of T4 to T3 - Answers -Beta blockers, lithium,
anticonvulsants, amiodorone
T or F: T3 therapy is antiarrhythmic - Answers -T. T3 shortens the QT interval and makes lethal
arrhythmias less likely.
T or F: Low T3 is the strongest predictor of death in cardiac patients; more than lipids or EF -
Answers -T
Dosing of Testosterone in various forms - Answers -cream 50-150 mg / day
Cypionate 50-150 mg / week
1|Page
,pellets 75 mg (5-10) every 3 months
HCG 1000-5000 IU / week
Functional biomarkers for measuring calcium - Answers -bone resorption markers, serum 25-
OHD, PTH
Direct markers for measuring calcium - Answers -hair, urine
Main estrogen produced before menopause - Answers -Estradiol
Functions of estradiol - Answers -Increases HDL; decreases LDL; decreases triglycerides;
increases GH; increases serotonin; increases endorphins; improves sleep; decreases fatigue;
maintains memory; antioxidant status; helps maintain potassium and absorb calcium, Mg, zinc
T or F: estriol is 80 times weaker than estradiol - Answers -T
Actions of progesterone in body - Answers -Natural diuretic; increases scalp hair; enhances
action of thyroid hormones; relaxes smooth muscle; neuroprotective; anti-inflammatory;
prevents menstrual migraine headaches; calming; stimulates production of new bone; lowers
cholesterol; protects breast tissue from overstimulation from E
2|Page
,non-pharmacologic ways to boost T - Answers -Decrease caloric intake; increase protein in diet;
exercise; amino acids (arginine, leucine, glutamine); sleep; lose weight; stress reduction; zinc
T or F: 20% of women have high T levels as they go through menopause - Answers -T
Where do immune reactions such as antigen interaction with APC's take place? - Answers -
secondary lymphoid organs - spleen, lymph nodes, tonsils, etc
Most abundant immune cell in circulation - Answers -polymophonuclear granulocytes.
Comprise 60-70% of circulating lymphocytes. Protect by phagocytosis.
Most common type of granulocyte. - Answers -Neutrophils - 90%
Percentage of eosinophils in circulation - Answers -2-5%
Where are mast cells found? - Answers -F. Mast cells are mainly found in connective tissues of
body. They can; however, enter the brain from the blood during brain injury.
Percentage of B cells in circulation - Answers -5-15%
3|Page
, How does Th1 stimulate immune response? - Answers -Th1 operates primarily through
macrophage and produces cytokines including IL-2; TGF-beta and IL-10. Also stimulates
cytotoxic T cells.
How do Th2 cells operate on immune system? - Answers -Th2 cells operate primarily through B
cells and release cytokines including IL-4, IL-5, IL-6, IL-10, and TGF-beta, helping to promote
antibody production
T or F: Asthma is associated with a TH1 response - Answers -F. Asthma involves Th2 response.
Examples of antigen presenting cells - Answers -Microglia in brain; Langerhans cells in skin
Most common immunoglobulin in circulation - Answers -IGG makes up 75% of total Ab. Most
efficient against viruses and microbial toxins. Triggers C1 of complement chain. Provides passive
immune defense to fetus in utero and to infant in first 6 months of life.
Antibody that protects mucosal surfaces - Answers -IgA.
T or F: Colostrum is rich in IgA. IgA protects newborn baby by reducing pathogen multiplication.
- Answers -T
4|Page
100% Solutions (2026/2027) Grade: A+|Status: Guaranteed
Pass) – A4M001 Endocrinology, Cardiology & Neurology Q&A –
American Academy of Anti-Aging Medicine
What is the endopat test? - Answers -Endopat is a measure of endothelial function. Endopat
measures the vascular flow in a patient's arm after occlusion. Post occlusion dilation should be
greater in the control arm due to release of NO.
Sensitivity of SPECT scan for diagnosing Alzheimer's dz - Answers -74%
Medications that decrease conversion of T4 to T3 - Answers -Beta blockers, lithium,
anticonvulsants, amiodorone
T or F: T3 therapy is antiarrhythmic - Answers -T. T3 shortens the QT interval and makes lethal
arrhythmias less likely.
T or F: Low T3 is the strongest predictor of death in cardiac patients; more than lipids or EF -
Answers -T
Dosing of Testosterone in various forms - Answers -cream 50-150 mg / day
Cypionate 50-150 mg / week
1|Page
,pellets 75 mg (5-10) every 3 months
HCG 1000-5000 IU / week
Functional biomarkers for measuring calcium - Answers -bone resorption markers, serum 25-
OHD, PTH
Direct markers for measuring calcium - Answers -hair, urine
Main estrogen produced before menopause - Answers -Estradiol
Functions of estradiol - Answers -Increases HDL; decreases LDL; decreases triglycerides;
increases GH; increases serotonin; increases endorphins; improves sleep; decreases fatigue;
maintains memory; antioxidant status; helps maintain potassium and absorb calcium, Mg, zinc
T or F: estriol is 80 times weaker than estradiol - Answers -T
Actions of progesterone in body - Answers -Natural diuretic; increases scalp hair; enhances
action of thyroid hormones; relaxes smooth muscle; neuroprotective; anti-inflammatory;
prevents menstrual migraine headaches; calming; stimulates production of new bone; lowers
cholesterol; protects breast tissue from overstimulation from E
2|Page
,non-pharmacologic ways to boost T - Answers -Decrease caloric intake; increase protein in diet;
exercise; amino acids (arginine, leucine, glutamine); sleep; lose weight; stress reduction; zinc
T or F: 20% of women have high T levels as they go through menopause - Answers -T
Where do immune reactions such as antigen interaction with APC's take place? - Answers -
secondary lymphoid organs - spleen, lymph nodes, tonsils, etc
Most abundant immune cell in circulation - Answers -polymophonuclear granulocytes.
Comprise 60-70% of circulating lymphocytes. Protect by phagocytosis.
Most common type of granulocyte. - Answers -Neutrophils - 90%
Percentage of eosinophils in circulation - Answers -2-5%
Where are mast cells found? - Answers -F. Mast cells are mainly found in connective tissues of
body. They can; however, enter the brain from the blood during brain injury.
Percentage of B cells in circulation - Answers -5-15%
3|Page
, How does Th1 stimulate immune response? - Answers -Th1 operates primarily through
macrophage and produces cytokines including IL-2; TGF-beta and IL-10. Also stimulates
cytotoxic T cells.
How do Th2 cells operate on immune system? - Answers -Th2 cells operate primarily through B
cells and release cytokines including IL-4, IL-5, IL-6, IL-10, and TGF-beta, helping to promote
antibody production
T or F: Asthma is associated with a TH1 response - Answers -F. Asthma involves Th2 response.
Examples of antigen presenting cells - Answers -Microglia in brain; Langerhans cells in skin
Most common immunoglobulin in circulation - Answers -IGG makes up 75% of total Ab. Most
efficient against viruses and microbial toxins. Triggers C1 of complement chain. Provides passive
immune defense to fetus in utero and to infant in first 6 months of life.
Antibody that protects mucosal surfaces - Answers -IgA.
T or F: Colostrum is rich in IgA. IgA protects newborn baby by reducing pathogen multiplication.
- Answers -T
4|Page
