COMLEX-USA Level 2-CE COMLEX-USA Level 2-
CE 150 Advanced Multisystem Clinical
Reasoning Questions with Integrated
Osteopathic Principles, Viscerosomatic
Correlation, and High-Complexity Vignette
Rationales — V2.0 Enhanced Edition for
the September 10–October 9 Testing
Window.
Table of Contents
Question
Section Topic
Numbers
Osteopathic Principles, Somatic
I Dysfunction & Advanced 1–20
T.A.R.T. Integration
II Osteopathic Manipulative 21–45
Treatment: Technique Selection,
, Question
Section Topic
Numbers
Contraindications & Clinical
Sequencing
Chapman Points,
Viscerosomatic &
III 46–65
Somatovisceral Reflexes in
Complex Clinical Contexts
Cardiovascular System: Acute
Coronary Syndromes,
IV 66–80
Arrhythmias, Heart Failure &
Vascular Emergencies
Respiratory System:
Obstructive, Restrictive &
V 81–90
Infectious Diseases with OMM
Integration
, Question
Section Topic
Numbers
Gastrointestinal & Nutritional:
VI Hepatobiliary, Pancreatic & 91–105
Bowel Disorders
Musculoskeletal System:
Complex Regional Pain,
VII 106–120
Radiculopathy & Inflammatory
Arthropathies
Nervous System & Mental
Health: Stroke, Demyelinating
VIII 121–132
Disease & Psychiatric
Emergencies
Obstetrics, Gynecology &
IX 133–140
Genitourinary Systems
Ethics, Professionalism &
X Medical Law: Complex 141–148
Decision-Making
, Question
Section Topic
Numbers
Biostatistics & Epidemiology:
XI Study Design, Bias & Clinical 149–150
Application
SECTION I: OSTEOPATHIC PRINCIPLES, SOMATIC
DYSFUNCTION & ADVANCED T.A.R.T. INTEGRATION
(Questions 1–20)
🟢 1. A 58-year-old male with a 30-year history of type
2 diabetes mellitus presents with chronic bilateral
lower extremity burning dysesthesias and progressive
weakness. Osteopathic structural examination reveals
significant somatic dysfunction at T10–L2 with
paraspinal muscle hypertonicity, restricted segmental
motion, and a Chapman point at the right 12th rib
posteriorly. A tender point in the right gluteus medius
muscle belly reproduces the patient's radicular pain.
Which of the following represents the most
comprehensive osteopathic diagnostic formulation
incorporating both somatic and visceral components?
CE 150 Advanced Multisystem Clinical
Reasoning Questions with Integrated
Osteopathic Principles, Viscerosomatic
Correlation, and High-Complexity Vignette
Rationales — V2.0 Enhanced Edition for
the September 10–October 9 Testing
Window.
Table of Contents
Question
Section Topic
Numbers
Osteopathic Principles, Somatic
I Dysfunction & Advanced 1–20
T.A.R.T. Integration
II Osteopathic Manipulative 21–45
Treatment: Technique Selection,
, Question
Section Topic
Numbers
Contraindications & Clinical
Sequencing
Chapman Points,
Viscerosomatic &
III 46–65
Somatovisceral Reflexes in
Complex Clinical Contexts
Cardiovascular System: Acute
Coronary Syndromes,
IV 66–80
Arrhythmias, Heart Failure &
Vascular Emergencies
Respiratory System:
Obstructive, Restrictive &
V 81–90
Infectious Diseases with OMM
Integration
, Question
Section Topic
Numbers
Gastrointestinal & Nutritional:
VI Hepatobiliary, Pancreatic & 91–105
Bowel Disorders
Musculoskeletal System:
Complex Regional Pain,
VII 106–120
Radiculopathy & Inflammatory
Arthropathies
Nervous System & Mental
Health: Stroke, Demyelinating
VIII 121–132
Disease & Psychiatric
Emergencies
Obstetrics, Gynecology &
IX 133–140
Genitourinary Systems
Ethics, Professionalism &
X Medical Law: Complex 141–148
Decision-Making
, Question
Section Topic
Numbers
Biostatistics & Epidemiology:
XI Study Design, Bias & Clinical 149–150
Application
SECTION I: OSTEOPATHIC PRINCIPLES, SOMATIC
DYSFUNCTION & ADVANCED T.A.R.T. INTEGRATION
(Questions 1–20)
🟢 1. A 58-year-old male with a 30-year history of type
2 diabetes mellitus presents with chronic bilateral
lower extremity burning dysesthesias and progressive
weakness. Osteopathic structural examination reveals
significant somatic dysfunction at T10–L2 with
paraspinal muscle hypertonicity, restricted segmental
motion, and a Chapman point at the right 12th rib
posteriorly. A tender point in the right gluteus medius
muscle belly reproduces the patient's radicular pain.
Which of the following represents the most
comprehensive osteopathic diagnostic formulation
incorporating both somatic and visceral components?
