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A pharmacist is counseling a 58-year-old man with a new prescription for repaglinide
0.5 mg t.i.d. According to the patient profile, he is homeless. Which of the following
information should be requested from the patient and what is the rationale?
A) Are you eating three regular meals per day? Drug is taken with meals and skipped if meal
is skipped.
B) Do you have a refrigerator to store the medication? Drug must be refrigerated.
C) Are you able to afford the medication? Drug is expensive.
D) Do you have a caregiver to administer the medication? Drug requires supervision.
Rationale: Repaglinide is taken with meals and skipped if a meal is skipped. Because the
patient is homeless, the pharmacist must assess whether he is eating three regular meals
per day to ensure safe and effective use. Refrigeration, cost, and caregiver supervision are
not primary concerns for repaglinide.
What could be considered barriers to providing a thorough oral consultation to a
patient?
A) Educational background
B) Primary language
C) Physical impairment
D) All of the above
Rationale: Educational background, primary language, and physical impairment can all be
barriers to providing a thorough oral consultation. The pharmacist must adapt
communication to ensure understanding.
A hospital pharmacist has just received a new medication order for brimonidine. The
pharmacist wishes to confirm the appropriateness of this order and calls the nurse for
the patient's diagnosis. What diagnoses would confirm that the brimonidine order is
APPROPRIATE?
A) Glaucoma
B) Hypertension
,C) Diabetes
D) Asthma
Rationale: Brimonidine is an alpha-2 adrenergic agonist used to treat glaucoma. It lowers
intraocular pressure. Hypertension, diabetes, and asthma are not indications for
brimonidine.
A physician writes the following prescription: Finasteride 1 mg tablets #30, 1 tab p.o.
daily for benign prostatic hyperplasia. What would be the MOST APPROPRIATE action
of the pharmacist?
A) Call physician regarding dosage strength.
B) Fill the prescription as written.
C) Dispense 5 mg tablets instead.
D) Refuse to fill the prescription.
Rationale: Finasteride 1 mg is indicated for male pattern hair loss, not benign prostatic
hyperplasia (BPH). The dose for BPH is 5 mg daily. The pharmacist should call the physician
regarding the dosage strength.
Which of the following is CORRECT about a prescription for naproxen sodium 275 mg
tablets #20 Sig: i tab b.i.d.?
A) Naproxen sodium at that dosage may be sold without a prescription as a product called
Aleve®.
B) The prescription may be filled as written.
C) The prescription may be filled with Naprosyn® if Anaprox® is not available.
D) Naproxen sodium at that dosage should not be given b.i.d.
Rationale: Naproxen sodium 275 mg is available over the counter as Aleve®. The
prescription may be filled as written. Naprosyn® is naproxen (not naproxen sodium) and is
not automatically substitutable. The dosage may be given b.i.d.
The pharmacist receives a telephone prescription for testosterone patches from a
physician's nurse. Assuming that the dosage, quantity, and instructions are
appropriate, and the prescription is reduced to writing, the pharmacist should:
A) Fill the prescription after noting the physician's and the nurse's names on the
prescription.
B) Refuse to fill the prescription.
C) Fill the prescription only after speaking directly to the physician.
D) Fill the prescription but not note the nurse's name.
,Rationale: Testosterone is a Schedule III controlled substance. A telephone prescription
from a physician's nurse is acceptable if the prescription is reduced to writing and both the
physician's and nurse's names are noted. The pharmacist should fill the prescription after
documenting both names.
A pharmacist receives a security prescription from a known local medical group for
promethazine with codeine. The prescription blank has the physician's name,
address, phone number, DEA number, and license number, but is signed only by a
physician's assistant (PA). The pharmacist's best course of action is to:
A) Call the medical group and request the PA's DEA number.
B) Fill the prescription as written.
C) Refuse to fill the prescription.
D) Ask the PA to sign the prescription.
Rationale: A physician's assistant may prescribe controlled substances if authorized. The
pharmacist should call the medical group to request the PA's DEA number to verify the
prescription's validity.
A patient brings in a prescription for Propecia® written by a known physician on a plain
piece of paper. The paper is not a prescription blank, but just a plain white sheet of
paper with all the needed information hand written. The pharmacist should:
A) Fill the prescription as written and file.
B) Refuse to fill the prescription.
C) Call the physician to verify.
D) Ask the patient to return with a proper prescription blank.
Rationale: Propecia® (finasteride 1 mg) is not a controlled substance. A prescription on
plain paper with all needed information is valid. The pharmacist should fill the prescription
as written and file it.
A 60-year-old woman who recently had a hysterectomy comes to the pharmacy with
new prescriptions for estradiol, ibuprofen, calcium carbonate, and
medroxyprogesterone. Which of the following drugs should be discussed with the
prescriber?
A) Medroxyprogesterone
B) Estradiol
C) Ibuprofen
D) Calcium carbonate
, Rationale: Medroxyprogesterone is a progestin typically used in hormone replacement
therapy for women with a uterus to prevent endometrial hyperplasia. After a hysterectomy,
the uterus is removed, so medroxyprogesterone is not needed. The pharmacist should
discuss this with the prescriber.
What would be the MOST APPROPRIATE auxiliary labels for a prescription for
clarithromycin 250 mg/5 mL?
A) Do not refrigerate and Shake well.
B) Refrigerate and Shake well.
C) Do not refrigerate and Do not shake.
D) Refrigerate and Do not shake.
Rationale: Clarithromycin suspension should not be refrigerated and should be shaken
well before each dose. Refrigeration can cause the suspension to thicken.
A pharmacy technician has prepared four IV piggyback doses of
sulfamethoxazole/trimethoprim for 24-hour dosing for a patient. The technician asked
the pharmacist to verify the medication before delivery to the patient ward. What is a
concern regarding the preparation?
A) Short-term drug stability
B) Incorrect drug
C) Incorrect dose
D) Incorrect route
Rationale: Sulfamethoxazole/trimethoprim IV piggyback doses have limited stability.
Preparing four doses for 24-hour dosing may exceed the stability period. The pharmacist
should be concerned about short-term drug stability.
A technician has prepared a 16-oz bulk supply of spironolactone suspension 1 mg/mL
to be packaged into 5 mg/5 mL oral syringes for future dispensing. The pharmacist
checking this preparation should ensure that the records include what?
A) Manufacturer's lot number
B) Package size and number of syringes prepared
C) Formula for the suspension
D) All of the above
Rationale: The records should include the manufacturer's lot number, package size and
number of syringes prepared, and the formula for the suspension. All of the above are
required for compounded preparations.