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REx-PN Pharmacology 2026 Practice Questions & Verified Answers | 162 Q&A Drug Classes, Suffixes & Nursing Considerations | Graded A+

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REx-PN Practice Questions – Pharmacology 2026 | Most Tested Questions & Verified Answers | Latest Update | Graded A+ A focused 162-question pharmacology bank with the correct answer marked on every item, built for REx-PN candidates in Ontario and British Columbia and equally useful for NCLEX-PN, LPN/LVN pharmacology courses, and med-surg exams. What's inside: - Drug suffix and prefix decoding – -sartan, -pril, -statin, -parin, -prazole, -terol, -vir, -cycline, -sone, -pam/-lam, -pine, -zem, -mil, -ase, and the cef-/ceph- prefix - Pharmacokinetics – absorption, distribution, metabolism, excretion, half-life, narrow therapeutic range, and how renal or hepatic impairment changes each stage - Cardiovascular – ACE inhibitors and the persistent cough, ARBs, calcium channel blockers, digoxin and bradycardia, ASA, anticoagulants, tPA in ischemic stroke, loop diuretics and hypokalemia - Anti-infectives – penicillin allergy and the hormonal contraceptive interaction, cephalosporin adverse effects, tetracyclines with dairy and in pregnancy, antivirals - Mental health meds – benzodiazepines, tricyclic antidepressants, phenothiazines, clozapine and absolute neutrophil count monitoring - Respiratory and GI – beta-2 agonists, inhaler technique, antacids, proton pump inhibitors, acetaminophen and liver function tests - Other high-yield agents – baclofen, dantrolene, ferrous gluconate, corticosteroids, statins Format: Clean PDF, question-and-answer layout with correct responses highlighted. Ideal for rapid self-quizzing, spotting weak drug classes, and last-minute review. Instant download after purchase.

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REx-PN Practice Questions – Pharmacology 2026 | Most
Tested Questions & Verified Answers | Latest Update |
Graded A+
1. What class of drugs is characterized by the suffix '-sartan'?

Angiotensin II receptor blockers (ARBs)

Calcium channel blockers

ACE inhibitors

Beta-blockers

2. Describe the primary action of cephalosporins in the treatment of infections.

Cephalosporins enhance protein synthesis in bacteria.

Cephalosporins neutralize bacterial toxins.

Cephalosporins work by inhibiting bacterial cell wall synthesis.

Cephalosporins disrupt DNA replication in bacteria.

3. Drugs usually ending in -sone are associated with

Antilipemic

ACE Inhibitor

Steroids

Antivirals

4. Describe the primary action of benzodiazepines in the body.

Benzodiazepines increase heart rate and blood pressure.

Benzodiazepines block the reuptake of dopamine.

, Benzodiazepines act as central nervous system depressants,
enhancing the effect of the neurotransmitter GABA.

Benzodiazepines stimulate the release of serotonin in the brain.

5. What drug class does acetylsalicylic acid (ASA) belong to?

Anticoagulants

Antiplatelet agents

Antibiotics

ACE inhibitors

6. Describe the significance of timing when administering Loop Diuretics.

Timing is irrelevant as Loop Diuretics work the same regardless of
when they are given.

Administering Loop Diuretics in the morning helps prevent nocturia
and promotes effective fluid management.

Administering Loop Diuretics at night is preferred to avoid daytime
side effects.

Loop Diuretics should be given at any time to ensure maximum
absorption.

7. The nurse giving Acetaminophen understands this medication belongs to
what drug class?

non-opioid analgesic

benzodiazepine

opioid analgesic

NSAID

,8. A patient is prescribed acetylsalicylic acid (ASA) after a myocardial infarction.
What is a critical nursing responsibility when administering this medication?

Evaluate renal function.

Monitor for signs of bleeding.

Check blood glucose levels.

Assess for respiratory distress.

9. Describe how Phenothiazine medications affect the central nervous system
and the implications for patient care.

Phenothiazine medications can cause sedation and other central
nervous system effects, requiring careful monitoring of patients'
alertness and safety.

Phenothiazine medications are only used for treating infections.

Phenothiazine medications have no significant effects on the central
nervous system.

Phenothiazine medications primarily affect the cardiovascular system,
leading to increased heart rate.

10. When should loop diuretics such as Furosemide be administered for
maximum effectiveness?

In the afternoon

In the middle of the night

In the evening

Early in the morning

, 11. Describe the importance of monitoring heart rate before giving digoxin to a
patient.

Monitoring heart rate is only important for patients with a history of
heart disease.

Monitoring heart rate helps determine the patient's blood pressure
response to digoxin.

Monitoring heart rate is unnecessary as digoxin does not affect heart
rhythm.

Monitoring heart rate is crucial because digoxin can cause
bradycardia, and administering it when the heart rate is too low can
lead to serious complications.

12. Describe the primary action of tetracyclines in the treatment of infections.

Tetracyclines disrupt cell wall synthesis.

Tetracyclines neutralize toxins.

Tetracyclines inhibit bacterial protein synthesis.

Tetracyclines enhance immune response.

13. A patient is prescribed a medication that ends with the suffix '-parin'. What
nursing responsibility is crucial for monitoring this patient?

Monitor blood glucose levels.

Monitor heart rate and rhythm.

Monitor for signs of infection.

Monitor for signs of bleeding.

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