NURS231 PATHOPHYSIOLOGY MODULE 1 EXAM
PREP 2026 COMPLETE QUESTIONS AND
ANSWERS REVIEW
◉ A 20-year-old pregnant female gives birth to a stillborn child.
Autopsy reveals that the fetus has 92 chromosomes. Which of the
following describes this condition?
A) Euploidy
B) Triploidy
C) Tetraploidy
D) Aneuploidy Answer: c
◉ If a person is a chromosomal mosaic, the person may:
A) be a carrier of the genetic disease.
B) have a mild form of the genetic disease.
C) have two genetic diseases.
D) be sterile as a result of the genetic disease. Answer: b
◉ The most common cause of Down syndrome is:
A) paternal nondisjunction.
B) maternal translocations.
C) maternal nondisjunction.
,D) paternal translocations. Answer: c
◉ Risk factors for Down syndrome include:
A) fetal exposure to mutagens in the uterus.
B) increased paternal age.
C) family history of Down syndrome.
D) pregnancy in women over age 35. Answer: d
◉ A 13-year-old girl has a karyotype that reveals an absent
homologous X chromosome with only a single X chromosome
present. Her condition is called:
A) Down syndrome.
B) Cri du chat syndrome.
C) Turner syndrome.
D) Edward syndrome Answer: c
◉ A child is diagnosed with cystic fibrosis. History reveals that the
child's parents are first cousins. Cystic fibrosis was most likely the
result of:
A) X inactivation.
B) genomic imprinting.
C) consanguinity.
D) obligate carriers. Answer: c
,◉ Joey, age 9, is admitted to a pediatric unit with Duchenne
muscular dystrophy. He inherited this condition through a:
A) sex-linked dominant trait.
B) sex-influenced trait.
C) sex-limited trait.
D) sex-linked recessive trait. Answer: d
◉ A 50-year-old male was recently diagnosed with Huntington
disease. Transmission of this disease is associated with:
A) penetrance.
B) recurrence risk.
C) expressivity.
D) delayed age of onset. Answer: d
◉ People who have neurofibromatosis will show varying degrees of
the disease; this is because of the genetic principle of:
A) penetrance.
B) expressivity.
C) dominance.
D) recessiveness. Answer: b
, ◉ Cystic fibrosis is caused by an _____ gene.
A) X-linked dominant
B) X-linked recessive
C) autosomal dominant
D) autosomal recessive Answer: d
◉ To express a polygenic trait:
A) genes must interact with the environment.
B) several genes must act together.
C) multiple mutations must occur in the same family.
D) in situ cloning must occur. Answer: b
◉ The gradual increase in height among the human population over
the past 100 years is an example of:
A) polygenic trait.
B) multifactorial trait.
C) crossing over.
D) recombination. Answer: b
◉ A couple has three offspring: one child with an autosomal
dominant disease trait and two who are normal. The father is
affected by the autosomal dominant disease, but the mother does
PREP 2026 COMPLETE QUESTIONS AND
ANSWERS REVIEW
◉ A 20-year-old pregnant female gives birth to a stillborn child.
Autopsy reveals that the fetus has 92 chromosomes. Which of the
following describes this condition?
A) Euploidy
B) Triploidy
C) Tetraploidy
D) Aneuploidy Answer: c
◉ If a person is a chromosomal mosaic, the person may:
A) be a carrier of the genetic disease.
B) have a mild form of the genetic disease.
C) have two genetic diseases.
D) be sterile as a result of the genetic disease. Answer: b
◉ The most common cause of Down syndrome is:
A) paternal nondisjunction.
B) maternal translocations.
C) maternal nondisjunction.
,D) paternal translocations. Answer: c
◉ Risk factors for Down syndrome include:
A) fetal exposure to mutagens in the uterus.
B) increased paternal age.
C) family history of Down syndrome.
D) pregnancy in women over age 35. Answer: d
◉ A 13-year-old girl has a karyotype that reveals an absent
homologous X chromosome with only a single X chromosome
present. Her condition is called:
A) Down syndrome.
B) Cri du chat syndrome.
C) Turner syndrome.
D) Edward syndrome Answer: c
◉ A child is diagnosed with cystic fibrosis. History reveals that the
child's parents are first cousins. Cystic fibrosis was most likely the
result of:
A) X inactivation.
B) genomic imprinting.
C) consanguinity.
D) obligate carriers. Answer: c
,◉ Joey, age 9, is admitted to a pediatric unit with Duchenne
muscular dystrophy. He inherited this condition through a:
A) sex-linked dominant trait.
B) sex-influenced trait.
C) sex-limited trait.
D) sex-linked recessive trait. Answer: d
◉ A 50-year-old male was recently diagnosed with Huntington
disease. Transmission of this disease is associated with:
A) penetrance.
B) recurrence risk.
C) expressivity.
D) delayed age of onset. Answer: d
◉ People who have neurofibromatosis will show varying degrees of
the disease; this is because of the genetic principle of:
A) penetrance.
B) expressivity.
C) dominance.
D) recessiveness. Answer: b
, ◉ Cystic fibrosis is caused by an _____ gene.
A) X-linked dominant
B) X-linked recessive
C) autosomal dominant
D) autosomal recessive Answer: d
◉ To express a polygenic trait:
A) genes must interact with the environment.
B) several genes must act together.
C) multiple mutations must occur in the same family.
D) in situ cloning must occur. Answer: b
◉ The gradual increase in height among the human population over
the past 100 years is an example of:
A) polygenic trait.
B) multifactorial trait.
C) crossing over.
D) recombination. Answer: b
◉ A couple has three offspring: one child with an autosomal
dominant disease trait and two who are normal. The father is
affected by the autosomal dominant disease, but the mother does
