NURS 5334 ADVANCED PHARMACOLOGY
TEST 1 FINAL REVIEW SHEET 2026 TEST
BANK QUESTIONS WITH SOLUTIONS
GRADED A+
⩥ SAAC (short acting anticholinergic) drugs
Answer: Ipratropium
Combivent
⩥ COPD and pulm. rehab
Answer: All stages should have pulmonary rehab to improve exercise
tolerance
⩥ How do you manage COPD exacerbation?
Answer: SABA
Systemic glucocorticoids
Antibiotics: esp. for smokers
Supplemental O2 for keep sat 88-92%
⩥ menstrual cycle phases
Answer: Follicular Phase: first half of cycle (day 1-14)
Luteal Phase: second half of cycle
,Full cycle takes 28 days
⩥ estrogen and sex characteristics
Answer: Reproductive tract & secondary sex charac.
Estrogens influence:
-Ductal growth in breast
-Thickening & cornification of vaginal epithelium
-Proliferation of uterine epithelium
-Copious secretion of thickened mucus from endocervical glands
⩥ Estrogen metabolic actions
Answer: Positive effect on bone mass-blocks bone resorption
Favorable effects on cholesterol levels
Blood coagulation
Glucose homeostasis: promote glucose uptake
⩥ Estrogen AE
Answer: Endometrial hyperplasia & carcinoma
Promotes existing breast cxr
Ovarian cxr
CV events
Nausea
,Increase risk of blood clots
others: Gallbladder dx, jaundice, HA, chloasma
⩥ Menopause female w/uterus
Answer: Needs estrogen AND progesterone
(estrogen can thicken lining of uterus> hyperplasia> high risk of
endometrial cxr)
⩥ Menopause female w/out uterus
Answer: Needs estrogen only
⩥ Estrogen and menopause
Answer: If started early> pt gets bone & cardiac benefits w/out cardiac
risks
⩥ Optimal time for hormone replacement
Answer: About 5 years
Give lowest dose to control vasomotor symptoms
Don't start w/hormone if pt on menopause over 5 yrs> at risk for clots
⩥ Estrogen therapeutic uses
Answer: Menopausal hormone
, Female hypogonadism
Acne
⩥ Estrogens are major substrates of
Answer: CYP1A2 and CYP3A4
Interacts w/ antiseizure, warfarin, etc.
⩥ Selective Estrogen Receptor Modulators (SERMs)
Answer: Tamoxifen
Toremifene
Raloxifene
*Benefits of estrogen while avoiding drawbacks
⩥ Duavee (conjugated estrogens/bazedoxifene) treats
Answer: vasomotor symptoms
osteoporosis in postmenopausal women
good for preventing breast cxr
⩥ Progestins: Therapeutic Uses
Answer: postmenopausal hormone therapy
amenorrhea
infertility
TEST 1 FINAL REVIEW SHEET 2026 TEST
BANK QUESTIONS WITH SOLUTIONS
GRADED A+
⩥ SAAC (short acting anticholinergic) drugs
Answer: Ipratropium
Combivent
⩥ COPD and pulm. rehab
Answer: All stages should have pulmonary rehab to improve exercise
tolerance
⩥ How do you manage COPD exacerbation?
Answer: SABA
Systemic glucocorticoids
Antibiotics: esp. for smokers
Supplemental O2 for keep sat 88-92%
⩥ menstrual cycle phases
Answer: Follicular Phase: first half of cycle (day 1-14)
Luteal Phase: second half of cycle
,Full cycle takes 28 days
⩥ estrogen and sex characteristics
Answer: Reproductive tract & secondary sex charac.
Estrogens influence:
-Ductal growth in breast
-Thickening & cornification of vaginal epithelium
-Proliferation of uterine epithelium
-Copious secretion of thickened mucus from endocervical glands
⩥ Estrogen metabolic actions
Answer: Positive effect on bone mass-blocks bone resorption
Favorable effects on cholesterol levels
Blood coagulation
Glucose homeostasis: promote glucose uptake
⩥ Estrogen AE
Answer: Endometrial hyperplasia & carcinoma
Promotes existing breast cxr
Ovarian cxr
CV events
Nausea
,Increase risk of blood clots
others: Gallbladder dx, jaundice, HA, chloasma
⩥ Menopause female w/uterus
Answer: Needs estrogen AND progesterone
(estrogen can thicken lining of uterus> hyperplasia> high risk of
endometrial cxr)
⩥ Menopause female w/out uterus
Answer: Needs estrogen only
⩥ Estrogen and menopause
Answer: If started early> pt gets bone & cardiac benefits w/out cardiac
risks
⩥ Optimal time for hormone replacement
Answer: About 5 years
Give lowest dose to control vasomotor symptoms
Don't start w/hormone if pt on menopause over 5 yrs> at risk for clots
⩥ Estrogen therapeutic uses
Answer: Menopausal hormone
, Female hypogonadism
Acne
⩥ Estrogens are major substrates of
Answer: CYP1A2 and CYP3A4
Interacts w/ antiseizure, warfarin, etc.
⩥ Selective Estrogen Receptor Modulators (SERMs)
Answer: Tamoxifen
Toremifene
Raloxifene
*Benefits of estrogen while avoiding drawbacks
⩥ Duavee (conjugated estrogens/bazedoxifene) treats
Answer: vasomotor symptoms
osteoporosis in postmenopausal women
good for preventing breast cxr
⩥ Progestins: Therapeutic Uses
Answer: postmenopausal hormone therapy
amenorrhea
infertility
