NR 605 DIAGNOSIS AND MANAGEMENT
IN PMHNP ACROSS THE LIFESPAN
QUESTIONS & ANSWERS
(CHAMBERLAIN) 100% GUARANTEE
PASS
1. A 45-year-old male with Schizophrenia is started on Clozapine after failing two other
antipsychotics. Which laboratory value requires immediate discontinuation of the medication
according to the Clozapine REMS program?
A. Absolute Neutrophil Count (ANC) of 1,200/mm3
B. White Blood Cell (WBC) count of 3,500/mm3
C. Absolute Neutrophil Count (ANC) of 900/mm3
D. Platelet count of 100,000/mm3
Answer: C
Conceptual Explanation: For the general population, Clozapine must be interrupted if the
ANC falls below 1,000/mm3. An ANC of 900/mm3 represents severe neutropenia.
2. Which cytochrome P450 enzyme is primarily responsible for the metabolism of many
psychotropic drugs and is known to be inhibited by Fluoxetine and Paroxetine?
A. CYP2D6
,B. CYP3A4
C. CYP1A2
D. CYP2C19
Answer: A
Conceptual Explanation: CYP2D6 is a major metabolic pathway for many antidepressants
and antipsychotics. Fluoxetine and Paroxetine are potent inhibitors of this enzyme, leading
to potential drug-drug interactions.
3. A 28-year-old female presents with rapid speech, decreased need for sleep for 5 days, and
increased goal-directed activity. She has no history of hospitalization or psychosis. What is
the most likely diagnosis?
A. Bipolar II Disorder, Hypomanic Episode
B. Bipolar I Disorder, Manic Episode
C. Cyclothymic Disorder
D. Major Depressive Disorder with anxious distress
Answer: A
Conceptual Explanation: Hypomania is characterized by at least 4 consecutive days of
symptoms that are distinct from the person’s non-depressed state but do not cause marked
impairment in social or occupational functioning, require hospitalization, or include
psychosis.
, 4. In the treatment of Opioid Use Disorder, which medication acts as a partial mu-opioid
agonist and a kappa-opioid antagonist?
A. Methadone
B. Naltrexone
C. Naloxone
D. Buprenorphine
Answer: D
Conceptual Explanation: Buprenorphine is a partial mu-agonist, which provides a ceiling
effect on respiratory depression and euphoria, making it safer than full agonists like
methadone.
5. A 72-year-old patient presents with sudden onset of confusion, visual hallucinations, and a
fluctuating level of consciousness. Which assessment tool is most appropriate for screening
this condition?
A. Confusion Assessment Method (CAM)
B. Mini-Mental State Examination (MMSE)
C. PHQ-9
D. MoCA
Answer: A
IN PMHNP ACROSS THE LIFESPAN
QUESTIONS & ANSWERS
(CHAMBERLAIN) 100% GUARANTEE
PASS
1. A 45-year-old male with Schizophrenia is started on Clozapine after failing two other
antipsychotics. Which laboratory value requires immediate discontinuation of the medication
according to the Clozapine REMS program?
A. Absolute Neutrophil Count (ANC) of 1,200/mm3
B. White Blood Cell (WBC) count of 3,500/mm3
C. Absolute Neutrophil Count (ANC) of 900/mm3
D. Platelet count of 100,000/mm3
Answer: C
Conceptual Explanation: For the general population, Clozapine must be interrupted if the
ANC falls below 1,000/mm3. An ANC of 900/mm3 represents severe neutropenia.
2. Which cytochrome P450 enzyme is primarily responsible for the metabolism of many
psychotropic drugs and is known to be inhibited by Fluoxetine and Paroxetine?
A. CYP2D6
,B. CYP3A4
C. CYP1A2
D. CYP2C19
Answer: A
Conceptual Explanation: CYP2D6 is a major metabolic pathway for many antidepressants
and antipsychotics. Fluoxetine and Paroxetine are potent inhibitors of this enzyme, leading
to potential drug-drug interactions.
3. A 28-year-old female presents with rapid speech, decreased need for sleep for 5 days, and
increased goal-directed activity. She has no history of hospitalization or psychosis. What is
the most likely diagnosis?
A. Bipolar II Disorder, Hypomanic Episode
B. Bipolar I Disorder, Manic Episode
C. Cyclothymic Disorder
D. Major Depressive Disorder with anxious distress
Answer: A
Conceptual Explanation: Hypomania is characterized by at least 4 consecutive days of
symptoms that are distinct from the person’s non-depressed state but do not cause marked
impairment in social or occupational functioning, require hospitalization, or include
psychosis.
, 4. In the treatment of Opioid Use Disorder, which medication acts as a partial mu-opioid
agonist and a kappa-opioid antagonist?
A. Methadone
B. Naltrexone
C. Naloxone
D. Buprenorphine
Answer: D
Conceptual Explanation: Buprenorphine is a partial mu-agonist, which provides a ceiling
effect on respiratory depression and euphoria, making it safer than full agonists like
methadone.
5. A 72-year-old patient presents with sudden onset of confusion, visual hallucinations, and a
fluctuating level of consciousness. Which assessment tool is most appropriate for screening
this condition?
A. Confusion Assessment Method (CAM)
B. Mini-Mental State Examination (MMSE)
C. PHQ-9
D. MoCA
Answer: A
