NR 605 FINAL EXAM – DIAGNOSIS AND
MANAGEMENT IN PSYCHIATRIC-
MENTAL HEALTH ACROSS THE
LIFESPAN QUESTIONS & ANSWERS
(CHAMBERLAIN) 100% GUARANTEE
PASS
1. Which neurobiological pathway is primarily associated with the negative symptoms and
cognitive impairment observed in Schizophrenia?
A. Mesolimbic pathway
B. Nigrostriatal pathway
C. Tuberoinfundibular pathway
D. Mesocortical pathway
Answer: D
Conceptual Explanation: Negative symptoms and cognitive impairment in schizophrenia
are hypothesized to be caused by hypodopaminergia in the mesocortical pathway,
particularly the prefrontal cortex.
2. A 28-year-old patient on Clozapine presents with a sudden fever of 102.4°F, sore throat,
and mouth sores. What is the most critical immediate laboratory test needed?
A. Creatinine phosphokinase (CPK)
,B. Fasting blood glucose
C. Liver function tests (LFTs)
D. Complete Blood Count (CBC) with differential
Answer: D
Conceptual Explanation: These symptoms are indicative of agranulocytosis, a potentially
fatal side effect of Clozapine. An absolute neutrophil count (ANC) via a CBC with differential
is required immediately.
3. Which of the following antidepressants is considered the first-line choice for a patient with
comorbid Major Depressive Disorder and chronic neuropathic pain?
A. Sertraline
B. Duloxetine
C. Bupropion
D. Escitalopram
Answer: B
Conceptual Explanation: Duloxetine is an SNRI (Serotonin-Norepinephrine Reuptake
Inhibitor) that is FDA-approved for both depression and chronic pain conditions such as
diabetic peripheral neuropathy and fibromyalgia.
, 4. In the treatment of Bipolar I Disorder, which medication is most effective at reducing the
risk of suicide?
A. Lithium
B. Valproate
C. Lamotrigine
D. Quetiapine
Answer: A
Conceptual Explanation: Lithium has strong clinical evidence for reducing the rate of
suicide in patients with mood disorders compared to other mood stabilizers.
5. A PMHNP is treating a 14-year-old for ADHD. The patient’s parents are concerned about
growth suppression. Which intervention is evidence-based to mitigate this concern?
A. Switching to an alpha-2 agonist immediately
B. Decreasing the dosage to the minimum effective level
C. Implementing drug holidays during weekends or school breaks
D. Supplementing the diet with high-protein shakes
Answer: C
Conceptual Explanation: Evidence suggests that ‘drug holidays’ from stimulants can allow
for catch-up growth in children, though the overall effect of stimulants on final adult height
is often minimal.
MANAGEMENT IN PSYCHIATRIC-
MENTAL HEALTH ACROSS THE
LIFESPAN QUESTIONS & ANSWERS
(CHAMBERLAIN) 100% GUARANTEE
PASS
1. Which neurobiological pathway is primarily associated with the negative symptoms and
cognitive impairment observed in Schizophrenia?
A. Mesolimbic pathway
B. Nigrostriatal pathway
C. Tuberoinfundibular pathway
D. Mesocortical pathway
Answer: D
Conceptual Explanation: Negative symptoms and cognitive impairment in schizophrenia
are hypothesized to be caused by hypodopaminergia in the mesocortical pathway,
particularly the prefrontal cortex.
2. A 28-year-old patient on Clozapine presents with a sudden fever of 102.4°F, sore throat,
and mouth sores. What is the most critical immediate laboratory test needed?
A. Creatinine phosphokinase (CPK)
,B. Fasting blood glucose
C. Liver function tests (LFTs)
D. Complete Blood Count (CBC) with differential
Answer: D
Conceptual Explanation: These symptoms are indicative of agranulocytosis, a potentially
fatal side effect of Clozapine. An absolute neutrophil count (ANC) via a CBC with differential
is required immediately.
3. Which of the following antidepressants is considered the first-line choice for a patient with
comorbid Major Depressive Disorder and chronic neuropathic pain?
A. Sertraline
B. Duloxetine
C. Bupropion
D. Escitalopram
Answer: B
Conceptual Explanation: Duloxetine is an SNRI (Serotonin-Norepinephrine Reuptake
Inhibitor) that is FDA-approved for both depression and chronic pain conditions such as
diabetic peripheral neuropathy and fibromyalgia.
, 4. In the treatment of Bipolar I Disorder, which medication is most effective at reducing the
risk of suicide?
A. Lithium
B. Valproate
C. Lamotrigine
D. Quetiapine
Answer: A
Conceptual Explanation: Lithium has strong clinical evidence for reducing the rate of
suicide in patients with mood disorders compared to other mood stabilizers.
5. A PMHNP is treating a 14-year-old for ADHD. The patient’s parents are concerned about
growth suppression. Which intervention is evidence-based to mitigate this concern?
A. Switching to an alpha-2 agonist immediately
B. Decreasing the dosage to the minimum effective level
C. Implementing drug holidays during weekends or school breaks
D. Supplementing the diet with high-protein shakes
Answer: C
Conceptual Explanation: Evidence suggests that ‘drug holidays’ from stimulants can allow
for catch-up growth in children, though the overall effect of stimulants on final adult height
is often minimal.
