1
NCLEX-RN EXAM (2026) With 100% VERIFIED ANSWERS
AND COMPLETE QUESTIONS AND ANSWERS GRADED A+
200 Advanced NCLEX-RN–Style Practice Questionsw
with answers & rationales
Questions 1–25: Safety, Infection Control, Fundamentals, and Assessment
1. A nurse enters the room of a client who is receiving a blood transfusion. The client reports
chills and lower back discomfort. What is the nurse's priority action?
A. Slow the transfusion rate
B. Stop the transfusion immediately
C. Administer prescribed acetaminophen
D. Obtain another set of vital signs
Answer: B
Rationale: Chills and back pain may indicate an acute transfusion reaction. The transfusion must
be stopped immediately to prevent further exposure.
2. Which client should the nurse assess first?
A. A client with chronic arthritis reporting pain of 6/10
B. A postoperative client requesting assistance with ambulation
C. A client with asthma who has increasing difficulty speaking
D. A client awaiting discharge instructions
Answer: C
Rationale: Difficulty speaking during an asthma exacerbation suggests severe respiratory
compromise. Airway and breathing take priority.
3. Which intervention is most effective for preventing healthcare-associated infections?
A. Wearing a surgical mask for every client
B. Performing hand hygiene consistently
C. Administering prophylactic antibiotics
D. Using sterile gloves for routine care
Answer: B
Rationale: Proper hand hygiene is the most fundamental and effective method for interrupting
transmission of microorganisms.
,2
4. A client with suspected pulmonary tuberculosis is admitted. Which precaution is appropriate?
A. Contact precautions
B. Droplet precautions
C. Airborne precautions
D. Protective isolation
Answer: C
Rationale: Tuberculosis is transmitted through airborne particles. Airborne precautions require
appropriate respiratory protection and an airborne infection isolation room when available.
5. A nurse is caring for a client with Clostridioides difficile. Which hand-hygiene method is most
appropriate after providing care?
A. Alcohol-based hand sanitizer only
B. Soap and water
C. Sterile water
D. Chlorhexidine solution only
Answer: B
Rationale: Soap and water physically remove spores and are preferred after caring for a client
with C. difficile.
6. A confused client repeatedly attempts to climb out of bed. Which intervention should the
nurse implement first?
A. Apply wrist restraints
B. Request a sedative prescription
C. Identify and address the cause of the behavior
D. Place the client in seclusion
Answer: C
Rationale: The nurse should first assess for reversible causes such as pain, hypoxia, urinary
retention, medication effects, or delirium before restrictive interventions.
7. Which finding requires immediate intervention in a client receiving oxygen by nasal cannula?
A. Dry nasal mucosa
B. Oxygen saturation of 94%
,3
C. Smoking while oxygen is in use
D. Respiratory rate of 18/min
Answer: C
Rationale: Oxygen supports combustion. Smoking near supplemental oxygen creates an
immediate fire hazard.
8. Which client statement demonstrates correct understanding of fall prevention?
A. “I will get up quickly so I don't become dizzy.”
B. “I will keep my call light within reach.”
C. “I should keep the bed in the highest position.”
D. “I can walk independently if I feel stable.”
Answer: B
Rationale: Keeping the call light accessible allows the client to request assistance before
attempting unsafe movement.
9. A nurse discovers a medication error immediately after administration. What should the
nurse do first?
A. Complete an incident report
B. Notify the pharmacy
C. Assess the client
D. Document that the medication was given incorrectly
Answer: C
Rationale: The client's immediate safety is the priority. Assessment determines whether the
error caused an adverse effect requiring intervention.
10. Which action violates sterile technique?
A. Keeping sterile objects above waist level
B. Opening a sterile package away from the body
C. Turning away from an open sterile field
D. Keeping the sterile field dry
Answer: C
Rationale: The nurse must maintain visual control of a sterile field. Turning away creates
uncertainty about contamination.
, 4
11. Which assessment finding is most concerning in a client receiving opioid analgesia?
A. Constipation
B. Nausea
C. Respiratory rate of 8/min
D. Mild drowsiness
Answer: C
Rationale: Significant respiratory depression is a potentially life-threatening opioid adverse
effect and requires immediate intervention.
12. A client becomes dizzy when standing. Which assessment is most appropriate?
A. Check orthostatic vital signs
B. Measure abdominal girth
C. Assess visual acuity
D. Obtain a peak expiratory flow rate
Answer: A
Rationale: Orthostatic vital signs help identify changes in blood pressure and pulse associated
with position changes.
13. Which client requires airborne precautions?
A. Client with influenza
B. Client with tuberculosis
C. Client with MRSA wound infection
D. Client with C. difficile diarrhea
Answer: B
Rationale: Tuberculosis requires airborne precautions. Influenza generally requires droplet
precautions, while MRSA and C. difficile may require contact precautions.
14. Which finding most strongly indicates fluid volume deficit?
A. Bounding pulse
B. Crackles
C. Orthostatic hypotension
D. Peripheral edema
NCLEX-RN EXAM (2026) With 100% VERIFIED ANSWERS
AND COMPLETE QUESTIONS AND ANSWERS GRADED A+
200 Advanced NCLEX-RN–Style Practice Questionsw
with answers & rationales
Questions 1–25: Safety, Infection Control, Fundamentals, and Assessment
1. A nurse enters the room of a client who is receiving a blood transfusion. The client reports
chills and lower back discomfort. What is the nurse's priority action?
A. Slow the transfusion rate
B. Stop the transfusion immediately
C. Administer prescribed acetaminophen
D. Obtain another set of vital signs
Answer: B
Rationale: Chills and back pain may indicate an acute transfusion reaction. The transfusion must
be stopped immediately to prevent further exposure.
2. Which client should the nurse assess first?
A. A client with chronic arthritis reporting pain of 6/10
B. A postoperative client requesting assistance with ambulation
C. A client with asthma who has increasing difficulty speaking
D. A client awaiting discharge instructions
Answer: C
Rationale: Difficulty speaking during an asthma exacerbation suggests severe respiratory
compromise. Airway and breathing take priority.
3. Which intervention is most effective for preventing healthcare-associated infections?
A. Wearing a surgical mask for every client
B. Performing hand hygiene consistently
C. Administering prophylactic antibiotics
D. Using sterile gloves for routine care
Answer: B
Rationale: Proper hand hygiene is the most fundamental and effective method for interrupting
transmission of microorganisms.
,2
4. A client with suspected pulmonary tuberculosis is admitted. Which precaution is appropriate?
A. Contact precautions
B. Droplet precautions
C. Airborne precautions
D. Protective isolation
Answer: C
Rationale: Tuberculosis is transmitted through airborne particles. Airborne precautions require
appropriate respiratory protection and an airborne infection isolation room when available.
5. A nurse is caring for a client with Clostridioides difficile. Which hand-hygiene method is most
appropriate after providing care?
A. Alcohol-based hand sanitizer only
B. Soap and water
C. Sterile water
D. Chlorhexidine solution only
Answer: B
Rationale: Soap and water physically remove spores and are preferred after caring for a client
with C. difficile.
6. A confused client repeatedly attempts to climb out of bed. Which intervention should the
nurse implement first?
A. Apply wrist restraints
B. Request a sedative prescription
C. Identify and address the cause of the behavior
D. Place the client in seclusion
Answer: C
Rationale: The nurse should first assess for reversible causes such as pain, hypoxia, urinary
retention, medication effects, or delirium before restrictive interventions.
7. Which finding requires immediate intervention in a client receiving oxygen by nasal cannula?
A. Dry nasal mucosa
B. Oxygen saturation of 94%
,3
C. Smoking while oxygen is in use
D. Respiratory rate of 18/min
Answer: C
Rationale: Oxygen supports combustion. Smoking near supplemental oxygen creates an
immediate fire hazard.
8. Which client statement demonstrates correct understanding of fall prevention?
A. “I will get up quickly so I don't become dizzy.”
B. “I will keep my call light within reach.”
C. “I should keep the bed in the highest position.”
D. “I can walk independently if I feel stable.”
Answer: B
Rationale: Keeping the call light accessible allows the client to request assistance before
attempting unsafe movement.
9. A nurse discovers a medication error immediately after administration. What should the
nurse do first?
A. Complete an incident report
B. Notify the pharmacy
C. Assess the client
D. Document that the medication was given incorrectly
Answer: C
Rationale: The client's immediate safety is the priority. Assessment determines whether the
error caused an adverse effect requiring intervention.
10. Which action violates sterile technique?
A. Keeping sterile objects above waist level
B. Opening a sterile package away from the body
C. Turning away from an open sterile field
D. Keeping the sterile field dry
Answer: C
Rationale: The nurse must maintain visual control of a sterile field. Turning away creates
uncertainty about contamination.
, 4
11. Which assessment finding is most concerning in a client receiving opioid analgesia?
A. Constipation
B. Nausea
C. Respiratory rate of 8/min
D. Mild drowsiness
Answer: C
Rationale: Significant respiratory depression is a potentially life-threatening opioid adverse
effect and requires immediate intervention.
12. A client becomes dizzy when standing. Which assessment is most appropriate?
A. Check orthostatic vital signs
B. Measure abdominal girth
C. Assess visual acuity
D. Obtain a peak expiratory flow rate
Answer: A
Rationale: Orthostatic vital signs help identify changes in blood pressure and pulse associated
with position changes.
13. Which client requires airborne precautions?
A. Client with influenza
B. Client with tuberculosis
C. Client with MRSA wound infection
D. Client with C. difficile diarrhea
Answer: B
Rationale: Tuberculosis requires airborne precautions. Influenza generally requires droplet
precautions, while MRSA and C. difficile may require contact precautions.
14. Which finding most strongly indicates fluid volume deficit?
A. Bounding pulse
B. Crackles
C. Orthostatic hypotension
D. Peripheral edema
